4.5 Article

Liquid-crystalline behaviours of novel chitosan derivates containing singular and cholesteryl groups

Journal

LIQUID CRYSTALS
Volume 36, Issue 5, Pages 455-460

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/02678290903006215

Keywords

chitosan; lyotropic liquid crystal; cholesteric; solubility

Funding

  1. National Natural Science Fundamental Committee of China
  2. HI-Tech Research and development program (863) of China
  3. commission for science, technology and industry for national defence of China [DBDX2008038]
  4. Liaoning Province
  5. Science and Technology Department of Liaoning Province

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A series of esters of chitosan with cholesteryl hexanoate and cholesteryl decanoate side chains were synthesised. These compounds had higher solubilities than chitosan itself and all formed cholesteric lyotropic liquid crystalline phases. They had enhanced mesogenic properties as compared with the parent polymer. We consider that these compounds may prove to be of value as vehicles for drug delivery.

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