Menhaden oil, but not safflower or soybean oil, aids in restoring the polyunsaturated fatty acid profile in the novel delta-6-desaturase null mouse

Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults

(2011) Diana M. Merino et al.   MOLECULAR GENETICS AND METABOLISM

Fat-1 gene modulates the fatty acid composition of femoral and vertebral phospholipids

(2010) Beatrice Y.Y. Lau et al.   Applied Physiology Nutrition and Metabolism

A decreased n-6/n-3 ratio in the fat-1 mouse is associated with improved glucose tolerance

(2010) Brennan K. Smith et al.   Applied Physiology Nutrition and Metabolism

Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism

(2010) Eva Lattka et al.   CURRENT OPINION IN LIPIDOLOGY

DHA Metabolism: Targeting the Brain and Lipoxygenation

(2010) M. Picq et al.   MOLECULAR NEUROBIOLOGY

Flaxseed oil reduces the growth of human breast tumors (MCF-7) at high levels of circulating estrogen

(2010) Jennifer S. Truan et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Does genetic variation in the Δ6-desaturase promoter modify the association between α-linolenic acid and the prevalence of metabolic syndrome?

(2009) Hong Truong et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Increased macrophage cholesterol biosynthesis and decreased cellular paraoxonase 2 (PON2) expression in Δ6-desaturase knockout (6-DS KO) mice: Beneficial effects of arachidonic acid

(2009) Mira Rosenblat et al.   ATHEROSCLEROSIS

Disruption of FADS2 gene in mice impairs male reproduction and causes dermal and intestinal ulceration

(2009) Chad K. Stroud et al.   JOURNAL OF LIPID RESEARCH

Docosahexaenoic acid supplementation fully restores fertility and spermatogenesis in male delta-6 desaturase-null mice

(2009) Manuel Roqueta-Rivera et al.   JOURNAL OF LIPID RESEARCH

Bioactive dietary long-chain fatty acids: emerging mechanisms of action

(2008) Robert S. Chapkin et al.   BRITISH JOURNAL OF NUTRITION

Δ6-Desaturase (FADS2) deficiency unveils the role of ω3- and ω6-polyunsaturated fatty acids

(2008) Wilhelm Stoffel et al.   EMBO JOURNAL