Article
Environmental Sciences
Mitra Arianmehr, Naser Karimi, Zahra Souri
Summary: This study investigated the role of sulfur and reduced glutathione in alleviating arsenic toxicity. The results showed that the application of sulfur and glutathione increased the fresh weight and chlorophyll content of the plants, inhibited hydrogen peroxide accumulation, and improved antioxidant responses.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
Fan Li, Xiaojing Wu, Hongli Liu, Mengqi Liu, Zhengkai Yue, Zhenyu Wu, Lei Liu, Fuchang Li
Summary: This study reveals that copper depletion enhances ferroptosis by causing mitochondrial perturbation and reducing antioxidative mechanisms.
Article
Environmental Sciences
Khadija Sossey Alaoui, Bernard Tychon, Sandrine Joachim, Alain Geffard, Katherine Nott, Sebastien Ronkart, Jean-Marc Porcher, Remy Beaudouin, Christelle Robert, Marie-Laure Fauconnier, Matthew Saive
Summary: The study aimed to assess the toxicity of a mixture of five pharmaceutical drugs using Fontinalis antipyretica as a bioindicator and bioaccumulator. Results showed that only carbamazepine and irbesartan were accumulated by the species, with bioaccumulation levels increasing with exposure time. Antioxidant enzymes were sensitive to the drug mixture, with higher activity observed in plants exposed to higher concentrations. Chlorophyll content decreased in exposed plants, but photosynthetic activity was restored after 5 months. Morphological characteristics were less impacted by the treatment.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Environmental Sciences
Muhammad Kamran, Dan Wang, Haifa Abdulaziz Sakit Alhaithloul, Suliman Mohammed Alghanem, Tariq Aftab, Kaizhi Xie, Yusheng Lu, Chaohong Shi, Jie Sun, Wenjie Gu, Peizhi Xu, Mona Hassan Soliman
Summary: The study investigated the potential role of exogenous jasmonic acid in mitigating chromium toxicity in leafy vegetables grown on metal contaminated soil. The results showed that jasmonic acid helped restore plant growth and physio-biochemical attributes by enhancing the regulation of antioxidant enzymes, ascorbate, glutathione, and glyoxalase system enzymes to suppress oxidative and carbonyl stress.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Article
Health Care Sciences & Services
Andreea-Daniela Meca, Adina Turcu-Stiolica, Elena Camelia Stanciulescu, Ana Marina Andrei, Floarea Mimi Nitu, Ileana Monica Banita, Marius Matei, Catalina-Gabriela Pisoschi
Summary: Tuberculosis is a global infectious disease with a complex pathogenesis. Recent studies have shown changes in oxidative parameters and antioxidant status in TB patients after anti-tubercular therapy. Monitoring TB based on oxidative stress and antioxidant status may be beneficial in disease management and progression.
JOURNAL OF PERSONALIZED MEDICINE
(2021)
Review
Biochemistry & Molecular Biology
Sophie Tieu, Armen Charchoglyan, Lauryn Paulsen, Lauri C. Wagter-Lesperance, Umesh K. Shandilya, Byram W. Bridle, Bonnie A. Mallard, Niel A. Karrow
Summary: N-acetylcysteine (NAC) is a therapeutic drug with multiple beneficial effects for treating various diseases. It possesses antioxidant, cytoprotective, anti-inflammatory, antimicrobial, and mucolytic properties. However, clinical trials have limitations and conflicting results regarding its effectiveness.
Review
Biochemistry & Molecular Biology
Mi Yang, Xiaofei Zhou, Xi Tan, Xincheng Huang, Lu Yuan, Zipeng Zhang, Yan Yang, Min Xu, Ying Wan, Zezhi Li
Summary: Alcohol dependence leads to oxidative stress in the body, as evident from the changes observed in the levels of oxidative stress biomarkers. This meta-analysis highlights the decreased activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) enzymes and lower levels of albumin, along with increased levels of malondialdehyde (MDA), vitamin B12, homocysteine, and bilirubin in patients with alcohol dependence.
Article
Biotechnology & Applied Microbiology
Md Nurealam Siddiqui, Mohammad Golam Mostofa, Md Mezanur Rahman, Md Tahjib-Ul-Arif, Ashim Kumar Das, Mohammed Mohi-Ud-Din, Md Motiar Rohman, Hafizur Rahman Hafiz, Md Mesbah Uddin Ansary, Lam-Son Phan Tran
Summary: The study showed that adding exogenous GSH can significantly alleviate the detrimental effects of complete submergence on rice, increasing its tolerance by promoting growth restoration through increasing levels of chlorophylls, carotenoids, soluble proteins, and proline, and mitigating oxidative damage.
JOURNAL OF BIOTECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Abbas Raza, Wei Xie, Kwan-Hyun Kim, Venkateshwara Rao Dronamraju, Jessica Williams, Robert Vince, Swati S. More
Summary: Supplementation of gamma-GT-resistant GSH analogue psi-GSH and its precursor dipeptide 2 showed potential as a therapeutic for Alzheimer's disease. Compound 2 exhibited antioxidant properties and protection against A beta(1-42)-aggregates, resulting in cognitive benefits and mitigation of oxidative stress and inflammatory pathology in an acute AD model.
Article
Biochemistry & Molecular Biology
Naveen Dixit
Summary: The study found that there is variation in salt tolerance among different varieties of IH, with some varieties maintaining high seed germination rates and root growth even under high concentrations of NaCl. V1 and V3 varieties demonstrated strong salt tolerance, while V4 was most susceptible to NaCl stress.
Review
Cell Biology
Domenico Lapenna
Summary: Glutathione (GSH) is an important low-molecular weight thiol nucleophile and reductant with multiple functions, including antioxidant protection, detoxification, and cell signaling. It works in concert with GSH-dependent enzymes and its levels decline during aging, although elevated GSH levels in elderly individuals with good health suggest a potential link to increased healthspan and lifespan.
AGEING RESEARCH REVIEWS
(2023)
Review
Biochemistry & Molecular Biology
Lena Palaniyappan, Min Tae M. Park, Peter Jeon, Roberto Limongi, Kun Yang, Akira Sawa, Jean Theberge
Summary: Schizophrenia is a disease with poor outcome, with mechanistic changes occurring years before the onset that may still be modifiable, particularly in relation to intracortical glutathione. Recent magnetic resonance spectroscopic studies have linked GSH to critical outcome measures across various stages of schizophrenia.
Article
Biochemistry & Molecular Biology
Hyeongyeong Kim, Hyung Joo Suh, Ki-Bae Hong, Eun-Jin Jung, Yejin Ahn
Summary: The protective effects of a mixture of cysteine and glutathione against ethanol-induced hangover and liver damage were investigated. The mixture improved alcohol-induced behavior and enhanced ethanol-metabolizing enzyme activity. It also reduced the levels of serum alcohol and acetaldehyde, and regulated the expression of antioxidant enzymes through the Nrf2 pathway.
Review
Biochemistry & Molecular Biology
Lucien Bettendorff
Summary: This review explains how the physicochemical properties of elements and molecules determine the concept of redox balance. It discusses the major redox couples involved in cellular redox balance and their antioxidant properties in defense against reactive oxygen species. It also emphasizes the interplay between metabolism, oxidative stress, and cellular compartmentation.
Article
Biochemistry & Molecular Biology
Mohammed Mohi-Ud-Din, Nurealam Siddiqui, Motiar Rohman, S. V. Krishna Jagadish, Jalal Uddin Ahmed, Mohamed M. Hassan, Akbar Hossain, Tofazzal Islam
Summary: This study investigated the physiological and biochemical responses of contrasting thermo-tolerant wheat varieties under heat stress conditions. Results showed that the heat-tolerant variety BG26 maintained higher cellular homeostasis and antioxidant activities compared to the heat susceptible variety Pavon. Hierarchical clustering and principal component analysis revealed that BG26 possesses a combination of biochemical responses tailoring antioxidant activities for higher tolerance.
Review
Food Science & Technology
Mayara de Souza Queiros, Rodolfo Lazaro Soares Viriato, Ana Paula Badan Ribeiro, Mirna Lucia Gigante
Summary: This review investigates modification strategies and demonstrates the potential of application of milk fat on a macro, micro, and nanoscale. Milk fat is a complex fat and modification techniques, including biological, physical, and chemical modifications, can be used to change its physicochemical properties for various applications in the food industry.
FOOD REVIEWS INTERNATIONAL
(2023)
Article
Food Science & Technology
Penelope Lacrisio Reis Menta, Maria Emilia Rabelo Andrade, Livia Furquim de Castro, Luisa Martins Trindade, Melissa Tainan Silva Dias, Josiane Erica Miyamoto, Raisa Magno dos Santos, Geovanni Dantas Cassali, Raquel Franco Leal, Ana Paula Badan Ribeiro, Renato Grimaldi, Leticia Martins Ignacio-Souza, Marcio Alberto Torsoni, Adriana Souza Torsoni, Valbert Nascimento Cardoso, Marciane Milanski
Summary: The study suggests that adding interesterified fat to a normal lipid diet may have adverse effects on intestinal mucosa, leading to increased intestinal permeability, bacterial translocation, and damage to the intestinal epithelium.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Food Science & Technology
Kivea Kassia de Paiva e Silva, Mayara de Souza Queiros, Ana Paula Badan Ribeiro, Mirna Lucia Gigante
Summary: The study evaluated the potential of modified anhydrous milk fat as an encapsulating material for Lactobacillus acidophilus LA3. Encapsulated L. acidophilus showed high viability after 60 days of storage, with lower temperatures resulting in microparticles with a dry, fine and dispersed appearance. In contrast, higher temperatures led to microparticles with a granular appearance and less dispersion.
INTERNATIONAL DAIRY JOURNAL
(2022)
Article
Environmental Sciences
Diogo Queiroz Almeida, Henrique Barros, Ana Isabel Ribeiro
Summary: Green and blue spaces have a positive impact on children's cognitive development and intelligence quotient (IQ). Specifically, this study found that the presence of green spaces near residential areas is associated with higher performance and global IQ among children. However, accessibility to blue spaces does not show a clear association with IQ.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Engineering, Chemical
Marcia P. Silva, Ana M. Ribeiro, Claudia G. Silva, Kyung Ho Cho, U-Hwang Lee, Joaquim L. Faria, Jose M. Loureiro, Jon-San Chang, Alirio E. Rodrigues, Alexandre Ferreira
Summary: The main objective of this study is to design an efficient adsorptive process to extract water from thin air using MIL-100(Fe) as the adsorbent. The study evaluated the suitability and affinity of MIL-100(Fe) towards CO2, N-2, O-2, and H2O through equilibrium and dynamic studies. The research also developed models and analyzed the adsorption behavior and regeneration capability of MIL-100(Fe) using various techniques.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Agricultural Economics & Policy
Felipe Furtini Haddad, Ana Paula Lima Ribeiro, Kelly Carvalho Vieira, Rafaela Correa Pereira, Joao de Deus Souza Carneiro
Summary: By surveying producers and consumers of specialty beers, this study identified an important convergence between producer perceptions and actual consumer behavior, and segmented consumers into different groups. The study also highlighted the practical and social implications, such as new product development and creating precise labels and packaging, in the specialty brewing industry.
BRITISH FOOD JOURNAL
(2023)
Article
Environmental Sciences
Mariana N. Miranda, Ana R. Lado Ribeiro, Adrian M. T. Silva, M. Fernando R. Pereira
Summary: This study investigates the influence of plastic aging on the sorption capacity and behavior of microplastics. The results show that aged microplastics have a higher sorption capacity for certain organic micropollutants compared to pristine microplastics. Phytotoxicity tests suggest that the behavior of microplastics in soil-plant systems is relatively stable and does not have significant toxic effects.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Biochemistry & Molecular Biology
Raquel Alves, Diogo Santos, Joana Jorge, Ana Cristina Goncalves, Steve Catarino, Henrique Girao, Joana Barbosa Melo, Ana Bela Sarmento-Ribeiro
Summary: Heat shock protein 90 (HSP90) plays a crucial role in stabilizing and protecting client proteins. Alvespimycin, an HSP90 inhibitor, has shown potential in overcoming imatinib resistance in chronic myeloid leukemia (CML) cell lines. This study found that Alvespimycin effectively reduced metabolic activity and induced cell death, apoptosis, and cell cycle arrest in imatinib-sensitive and imatinib-resistant CML cells. It also increased HSP70 expression as a marker of HSP90 inhibition. These findings suggest that Alvespimycin could be a promising therapeutic approach for CML treatment, even in cases of imatinib resistance.
Article
Biochemistry & Molecular Biology
Hugo Ribeiro, Raquel Alves, Joana Jorge, Ana Cristina Goncalves, Ana Bela Sarmento-Ribeiro, Manuel Teixeira-Verissimo, Marilia Dourado, Jose Paulo Andrade
Summary: This study found that certain membrane platelet proteins may serve as biomarkers for pain characterization. These biomarkers, including CD40, CD49f, CD62p, and CD61, can provide objective information about pain levels without relying on patient self-report. The identification of these biomarkers could lead to more effective pain management strategies.
Article
Nursing
Ana Cristina Ribeiro, Priscila Poli, Silvia Carla da Silva Andre Uehara
Summary: This observational, retrospective, and analytical study aimed to analyze the risk of mortality from COVID-19 in people with obesity. The results showed that obese individuals with COVID-19 had a 26% higher risk of death compared to those without obesity. The highest mortality risks were found in obese individuals in the 11 to 60 age groups, while obese women aged 31 to 50 years and elderly women over 71 years had the lowest mortality risk compared to obese men.
Review
Biochemistry & Molecular Biology
Maria Ines Costa, Ana Bela Sarmento-Ribeiro, Ana Cristina Goncalves
Summary: The trace element zinc plays various biological roles in controlling intercellular communication and intracellular events through the modulation of Zn-dependent proteins. Perturbed Zn homeostasis has been implicated in the pathogenesis of chronic human diseases.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Food Science & Technology
Isabel Costa Sousa, Raisa Moreira Dardaque Mucinhato, Carolina Bottini Prates, Lais Mariano Zanin, Diogo Thimoteo da Cunha, Vanessa Dias Capriles, Veridiana Vera de Rosso, Elke Stedefeldt
Summary: This study examined the predictors of consumers' intentions to use food labelling to make healthy food choices and prevent noncommunicable diseases before the implementation of the front-of-package labelling policy in Brazil. The results showed that attitudes, subjective norms, knowledge, and food literacy positively predicted the intention to use food labels to make healthy food choices.
FOOD RESEARCH INTERNATIONAL
(2023)
Review
Nursing
Bianca Chel da Silva, Ana Cristina Ribeiro, Silvia Carla da Silva Andre Uehara
Summary: This study conducted a scoping review to examine the relationship between socioeconomic factors and child mortality from COVID-19. The findings demonstrated that low income and residing in socially vulnerable areas are associated with increased mortality rates.
Article
Food Science & Technology
Mariele Rodrigues Moreira, Kelly Aparecida Caetano, Chiu Chih Ming, Ana Paula Badan Ribeiro, Caroline Dario Capitani
Summary: The aim of this study was to characterize crackers made with baru oil and partially defatted baru cake, which showed interesting nutritional benefits including dietary fiber, magnesium, zinc, manganese, iron, proteins, and lipids.
FOOD SCIENCE AND TECHNOLOGY
(2022)
Article
Engineering, Chemical
Vinicius V. Santana, Marlon S. Gama, Jose M. Loureiro, Alirio E. Rodrigues, Ana M. Ribeiro, Frederico W. Tavares, Amaro G. Barreto, Idelfonso B. R. Nogueira
Summary: This study explores the potential of physics-informed neural networks (PINNs) in addressing numerical problems in adsorption systems. By comparing with traditional numerical methods, it demonstrates the high accuracy of PINNs in numerical solutions.
