Clofarabine for the treatment of adult acute lymphoid leukemia: the Group for Research on Adult Acute Lymphoblastic Leukemia intergroup

Clofarabine-based chemotherapy for relapsed/refractory adult acute lymphoblastic leukemia and lymphoblastic lymphoma. The Spanish experience

(2012) Pere Barba et al.   AMERICAN JOURNAL OF HEMATOLOGY

Trastuzumab for treatment of refractory/relapsed HER2-positive adult B-ALL: results of a phase 2 GRAALL study

(2012) P. Chevallier et al.   BLOOD

Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies

(2012) N. Gokbuget et al.   BLOOD

Clofarabine, cyclophosphamide and etoposide for the treatment of relapsed or resistant acute leukemia in pediatric patients

(2012) Maurizio Miano et al.   LEUKEMIA & LYMPHOMA

Therapeutic approaches to modulating Notch signaling: Current challenges and future prospects

(2012) Casper Groth et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Pediatric-inspired intensified therapy of adult T-ALL reveals the favorable outcome of NOTCH1/FBXW7 mutations, but not of low ERG/BAALC expression: a GRAALL study

(2011) R. Ben Abdelali et al.   BLOOD

Phase 2 trial of clofarabine in combination with etoposide and cyclophosphamide in pediatric patients with refractory or relapsed acute lymphoblastic leukemia

(2011) N. Hijiya et al.   BLOOD

Early UK experience in the use of clofarabine in the treatment of relapsed and refractory paediatric acute lymphoblastic leukaemia

(2011) David O’Connor et al.   BRITISH JOURNAL OF HAEMATOLOGY

l-asparaginase loaded red blood cells in refractory or relapsing acute lymphoblastic leukaemia in children and adults: results of the GRASPALL 2005-01 randomized trial

(2011) Carine Domenech et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clofarabine with high dose cytarabine and granulocyte colony-stimulating factor (G-CSF) priming for relapsed and refractory acute myeloid leukaemia

(2011) Pamela S. Becker et al.   BRITISH JOURNAL OF HAEMATOLOGY

Targeting Epigenetics through Histone Deacetylase Inhibitors in Acute Lymphoblastic Leukemia

(2011) A. Mummery et al.   CURRENT CANCER DRUG TARGETS

Report of a Phase II Study of Clofarabine and Cytarabine in De Novo and Relapsed and Refractory AML Patients and in Selected Elderly Patients at High Risk for Anthracycline Toxicity

(2011) E. Agura et al.   ONCOLOGIST

Southwest Oncology Group Study S0530: a phase 2 trial of clofarabine and cytarabine for relapsed or refractory acute lymphocytic leukaemia

(2010) Anjali S. Advani et al.   BRITISH JOURNAL OF HAEMATOLOGY

A randomized study of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in elderly patients with acute lymphoblastic leukemia: the GRAALL-SA1 study

(2010) M. Hunault-Berger et al.   HAEMATOLOGICA

Outcome after relapse of acute lymphoblastic leukemia in adult patients included in four consecutive risk-adapted trials by the PETHEMA Study Group

(2010) A. Oriol et al.   HAEMATOLOGICA

European Development of Clofarabine as Treatment for Older Patients With Acute Myeloid Leukemia Considered Unsuitable for Intensive Chemotherapy

(2010) Alan K. Burnett et al.   JOURNAL OF CLINICAL ONCOLOGY

Clofarabine-based salvage chemotherapy for relapsed or refractory acute leukemia before allogeneic stem cell transplantation: results from a case series

(2010) Götz Ulrich Grigoleit et al.   LEUKEMIA & LYMPHOMA

Remission re-induction chemotherapy with clofarabine, topotecan, thiotepa, and vinorelbine for patients with relapsed or refractory leukemia

(2010) Peter G. Steinherz et al.   PEDIATRIC BLOOD & CANCER

Successful combination treatment of clofarabine, cytarabine, and gemtuzumab-ozogamicin in adult refractory B-acute lymphoblastic leukemia

(2009) Cristina Papayannidis et al.   AMERICAN JOURNAL OF HEMATOLOGY

The use of higher dose clofarabine in adults with relapsed acute lymphoblastic leukemia

(2009) Bradley A. McGregor et al.   AMERICAN JOURNAL OF HEMATOLOGY

Clofarabine, cyclophosphamide and etoposide as single-course re-induction therapy for children with refractory/multiple relapsed acute lymphoblastic leukaemia

(2009) Franco Locatelli et al.   BRITISH JOURNAL OF HAEMATOLOGY

Clofarabine for the treatment of adult acute myeloid leukemia

(2009) Xavier Thomas et al.   Future Oncology

Advanced Philadelphia chromosome positive acute lymphoblastic leukemia patients relapsed after treatment with tyrosine-kinase inhibitors: successful response to clofarabine and cyclophosphamide

(2009) A. Vitale et al.   HAEMATOLOGICA

Recent Progress in the Treatment of Acute Lymphoblastic Leukemia: Clofarabine

(2009) Sima Jeha   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Nelarabine for the Treatment of Patients with Relapsed or Refractory T-cell Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

(2009) Daniel J. DeAngelo   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Phase II Study of Clofarabine Monotherapy in Previously Untreated Older Adults With Acute Myeloid Leukemia and Unfavorable Prognostic Factors

(2009) Hagop M. Kantarjian et al.   JOURNAL OF CLINICAL ONCOLOGY

A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia

(2009) N Hijiya et al.   LEUKEMIA

PAX5 mutations occur frequently in adult B-cell progenitor acute lymphoblastic leukemia and PAX5 haploinsufficiency is associated with BCR-ABL1 and TCF3-PBX1 fusion genes: a GRAALL study

(2009) J Familiades et al.   LEUKEMIA

A prognostic scoring system for adult patients less than 60 years of age with acute lymphoblastic leukemia in first relapse

(2009) Anjali Advani et al.   LEUKEMIA & LYMPHOMA

Deletion ofIKZF1and Prognosis in Acute Lymphoblastic Leukemia

(2009) Charles G. Mullighan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Management of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)

(2009) O. G. Ottmann et al.   Hematology-American Society of Hematology Education Program

A randomized study of clofarabine versus clofarabine plus low-dose cytarabine as front-line therapy for patients aged 60 years and older with acute myeloid leukemia and high-risk myelodysplastic syndrome

(2008) S. Faderl et al.   BLOOD

Allogeneic SCT in refractory or relapsed adult ALL is effective without prior reinduction chemotherapy

(2008) T H Terwey et al.   BONE MARROW TRANSPLANTATION

Clofarabine combinations as acute myeloid leukemia salvage therapy

(2008) Stefan Faderl et al.   CANCER

Outcome of adults with acute lymphocytic leukemia after second salvage therapy

(2008) Susan O'Brien et al.   CANCER

Cytotoxic Nucleoside Analogues: Different Strategies to Improve their Clinical Efficacy

(2008) C. Galmarini et al.   CURRENT MEDICINAL CHEMISTRY

First isolated extramedullary relapse in children with B-cell precursor acute lymphoblastic leukaemia: Results of the Cooprall-97 study

(2008) Carine Domenech et al.   EUROPEAN JOURNAL OF CANCER

Chemoimmunotherapy Reinduction With Epratuzumab in Children With Acute Lymphoblastic Leukemia in Marrow Relapse: A Children's Oncology Group Pilot Study

(2008) Elizabeth A. Raetz et al.   JOURNAL OF CLINICAL ONCOLOGY

FDA Drug Approval Summary: Nelarabine (Arranon(R)) for the Treatment of T-Cell Lymphoblastic Leukemia/Lymphoma

(2008) M. H. Cohen et al.   ONCOLOGIST

The Treatment of Adults with Acute Lymphoblastic Leukemia

(2008) A. Fielding   Hematology-American Society of Hematology Education Program