A novel three-dimensional stromal-based model forin vitrochemotherapy sensitivity testing of leukemia cells

Effect of Conditioning Regimen Intensity on Acute Myeloid Leukemia Outcomes after Umbilical Cord Blood Transplantation

(2011) Betul Oran et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

p53 activation of mesenchymal stromal cells partially abrogates microenvironment-mediated resistance to FLT3 inhibition in AML through HIF-1 -mediated down-regulation of CXCL12

(2011) K. Kojima et al.   BLOOD

A phase 1 dose-escalation study of ARRY-520, a kinesin spindle protein inhibitor, in patients with advanced myeloid leukemias

(2011) Hanna Jean Khoury et al.   CANCER

Phase I studies of AVE9633, an anti-CD33 antibody-maytansinoid conjugate, in adult patients with relapsed/refractory acute myeloid leukemia

(2011) Simona Lapusan et al.   INVESTIGATIONAL NEW DRUGS

Further activation of FLT3 mutants by FLT3 ligand

(2011) R Zheng et al.   ONCOGENE

Cytotoxic Function of Umbilical Cord Blood Natural Killer Cells: Relevance to Adoptive Immunotherapy

(2011) Syh-Jae Lin et al.   PEDIATRIC HEMATOLOGY AND ONCOLOGY

Dose study of the multikinase inhibitor, LY2457546, in patients with relapsed acute myeloid leukemia to assess safety, pharmacokinetics, and pharmacodynamics

(2011) Volker Wacheck et al.   Cancer Management and Research

Activity of Anticancer Agents in a Three-Dimensional Cell Culture Model

(2010) Victor Sanjit Nirmalanandhan et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Enrichment of N-Cadherin and Tie2-bearing CD34+/CD38−/CD123+ leukemic stem cells by chemotherapy-resistance

(2010) Lei Zhi et al.   CANCER LETTERS

Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow

(2010) Kentaro Hosokawa et al.   Cell Stem Cell

Ectopic Human Mesenchymal Stem Cell-Coated Scaffolds in NOD/SCID Mice: An In Vivo Model of the Leukemia Niche

(2010) Sarah R. Vaiselbuh et al.   TISSUE ENGINEERING PART C-METHODS

The development of a three-dimensional scaffold for ex vivo biomimicry of human acute myeloid leukaemia

(2009) Teresa Mortera Blanco et al.   BIOMATERIALS

Biomimetic macroporous hydrogel scaffolds in a high-throughput screening format for cell-based assays

(2008) Maria B. Dainiak et al.   BIOTECHNOLOGY PROGRESS

N-Cadherin Expression Level Distinguishes Reserved versus Primed States of Hematopoietic Stem Cells

(2008) Jeffrey S. Haug et al.   Cell Stem Cell

The effect of the proteasome inhibitor bortezomib on acute myeloid leukemia cells and drug resistance associated with the CD34+ immature phenotype

(2008) E. Colado et al.   HAEMATOLOGICA

CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

(2008) J A Burger et al.   LEUKEMIA

Leukemic Cells Create Bone Marrow Niches That Disrupt the Behavior of Normal Hematopoietic Progenitor Cells

(2008) Angela Colmone et al.   SCIENCE