Occurrence and modulation of therapeutic targets of Aurora kinase inhibition in pediatric acute leukemia cells

Combining Histone Deacetylase Inhibitor Vorinostat with Aurora Kinase Inhibitors Enhances Lymphoma Cell Killing with Repression of c-Myc, hTERT, and microRNA Levels

(2011) L. Kretzner et al.   CANCER RESEARCH

Identification of Aneuploidy-Selective Antiproliferation Compounds

(2011) Yun-Chi Tang et al.   CELL

Aurora-C kinase supports mitotic progression in the absence of Aurora-B

(2011) Scott D. Slattery et al.   CELL CYCLE

Aurora B kinase inhibition in mitosis: Strategies for optimizing the use of Aurora kinase inhibitors such as AT9283

(2011) Jayne Curry et al.   CELL CYCLE

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy

(2011) L S Steelman et al.   LEUKEMIA

Aurora kinase inhibitors: novel small molecules with promising activity in acute myeloid and Philadelphia-positive leukemias

(2010) A S Moore et al.   LEUKEMIA

Cytotoxicity, drug combinability, and biological correlates of ABT-737 against acute lymphoblastic leukemia cells with MLL rearrangement

(2010) Aarthi Jayanthan et al.   PEDIATRIC BLOOD & CANCER

Aurora kinase inhibitor ZM447439 induces apoptosis via mitochondrial pathways

(2009) Minglun Li et al.   BIOCHEMICAL PHARMACOLOGY

Discovery and Development of Aurora Kinase Inhibitors as Anticancer Agents

(2009) John R. Pollard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells

(2009) P. Kaestner et al.   MOLECULAR CANCER THERAPEUTICS

Cell cycle kinases as therapeutic targets for cancer

(2009) Silvia Lapenna et al.   NATURE REVIEWS DRUG DISCOVERY

The novel histone deacetylase inhibitor, LBH589, induces expression of DNA damage response genes and apoptosis in Ph- acute lymphoblastic leukemia cells

(2008) A. Scuto et al.   BLOOD

Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell lines

(2008) D. Buglio et al.   BLOOD

Mechanism of apicidin-induced cell cycle arrest and apoptosis in Ishikawa human endometrial cancer cells

(2008) Mee Young Ahn et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Aurora Kinases as Anticancer Drug Targets

(2008) O. Gautschi et al.   CLINICAL CANCER RESEARCH

Fragment-Based Discovery of the Pyrazol-4-yl Urea (AT9283), a Multitargeted Kinase Inhibitor with Potent Aurora Kinase Activity†

(2008) Steven Howard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comparison of mutated ABL1 and JAK2 as oncogenes and drug targets in myeloproliferative disorders

(2008) C Walz et al.   LEUKEMIA

New Therapeutic Strategies in Acute Lymphoblastic Leukemia

(2008) Sima Jeha   SEMINARS IN HEMATOLOGY

Treatment of Childhood Acute Lymphoblastic Leukemia

(2008) Martin Stanulla et al.   SEMINARS IN HEMATOLOGY

Relapsed acute lymphoblastic leukemia: Current status and future opportunities

(2008) Theresa M. Harned et al.   Current Oncology Reports