BCR–ABL1 kinase-dependent alteration of mRNA metabolism: potential alternatives for therapeutic intervention

miR-328 Functions as an RNA Decoy to Modulate hnRNP E2 Regulation of mRNA Translation in Leukemic Blasts

(2010) Anna M. Eiring et al.   CELL

Micro-RNA response to imatinib mesylate in patients with chronic myeloid leukemia

(2010) S. Flamant et al.   HAEMATOLOGICA

Chronic myeloid leukemia: mechanisms of blastic transformation

(2010) Danilo Perrotti et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy: cellular and molecular mechanisms

(2010) Danielle Glick et al.   JOURNAL OF PATHOLOGY

Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor

(2010) Matthew R Janes et al.   NATURE MEDICINE

The proteomic signature of NPM/ALK reveals deregulation of multiple cellular pathways

(2009) M. S. Lim et al.   BLOOD

Depletion of the Poly(C)-binding Proteins αCP1 and αCP2 from K562 Cells Leads to p53-independent Induction of Cyclin-dependent Kinase Inhibitor (CDKN1A) and G1Arrest

(2009) Shelly A. Waggoner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

(2009) Cristian Bellodi et al.   JOURNAL OF CLINICAL INVESTIGATION

GATA-2 L359 V mutation is exclusively associated with CML progression but not other hematological malignancies and GATA-2 P250A is a novel single nucleotide polymorphism

(2009) Su-Jiang Zhang et al.   LEUKEMIA RESEARCH

MicroRNA expression profiling in Imatinib-resistant Chronic Myeloid Leukemia patients without clinically significant ABL1-mutations

(2009) Edurne San José-Enériz et al.   Molecular Cancer

Lin28 promotes transformation and is associated with advanced human malignancies

(2009) Srinivas R Viswanathan et al.   NATURE GENETICS

Novel pathway in Bcr-Abl signal transduction involves Akt-independent, PLC-γ1-driven activation of mTOR/p70S6-kinase pathway

(2009) B Markova et al.   ONCOGENE

Glycogen synthase kinase 3  missplicing contributes to leukemia stem cell generation

(2009) A. E. Abrahamsson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression

(2008) María J. Bueno et al.   CANCER CELL

BCR/ABL Inhibits Mismatch Repair to Protect from Apoptosis and Induce Point Mutations

(2008) T. Stoklosa et al.   CANCER RESEARCH

BCR/ABL and Other Kinases from Chronic Myeloproliferative Disorders Stimulate Single-Strand Annealing, an Unfaithful DNA Double-Strand Break Repair

(2008) K. Cramer et al.   CANCER RESEARCH

mRNA Silencing in Human Erythroid Cell Maturation

(2008) Isabel S. Naarmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells

(2008) Michael G. Kharas et al.   JOURNAL OF CLINICAL INVESTIGATION

An Intron-Derived Insertion/Truncation Mutation in the BCR-ABL Kinase Domain in Chronic Myeloid Leukemia Patients Undergoing Kinase Inhibitor Therapy

(2008) Jennifer Laudadio et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Identification of new microRNA genes and aberrant microRNA profiles in childhood acute lymphoblastic leukemia

(2008) D Schotte et al.   LEUKEMIA

Inhibition of Polysome Assembly Enhances Imatinib Activity against Chronic Myelogenous Leukemia and Overcomes Imatinib Resistance

(2008) M. Zhang et al.   MOLECULAR AND CELLULAR BIOLOGY

Down-Regulation of hsa-miR-10a in Chronic Myeloid Leukemia CD34+ Cells Increases USF2-Mediated Cell Growth

(2008) X. Agirre et al.   MOLECULAR CANCER RESEARCH

Lin28 Mediates the Terminal Uridylation of let-7 Precursor MicroRNA

(2008) Inha Heo et al.   MOLECULAR CELL

BCR–ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros

(2008) Charles G. Mullighan et al.   NATURE

A feedback loop comprising lin-28 and let-7 controls pre-let-7 maturation during neural stem-cell commitment

(2008) Agnieszka Rybak et al.   NATURE CELL BIOLOGY

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

(2008) M. A. Newman et al.   RNA

Selective Blockade of MicroRNA Processing by Lin28

(2008) S. R. Viswanathan et al.   SCIENCE

Identification of novel posttranscriptional targets of the BCR/ABL oncoprotein by ribonomics: requirement of E2F3 for BCR/ABL leukemogenesis

(2007) A. M. Eiring et al.   BLOOD