Review
Critical Care Medicine
Randal O. Dull, Robert G. Hahn
Summary: Fluid balance plays a crucial role in maintaining normal physiology, but can be disrupted by diseases and medications. Inflammatory conditions and anesthesia can lead to impaired fluid return and accumulation in the tissues, causing a range of circulatory dysregulation. Experimental studies have identified the involvement of inflammatory mediators and nitric oxide in this process, highlighting potential targets for therapeutic interventions.
Review
Business
Aleksandra Selezneva, Anna Veselova, Amitabh Anand
Summary: This paper presents a systematic literature review on business model transformation (BMT), identifying the main research streams, developing a conceptual model, and identifying potential directions for future research.
INTERNATIONAL JOURNAL OF EMERGING MARKETS
(2023)
Review
Neurosciences
Yashar Ahmadian, Kenneth D. Miller
Summary: Many studies have shown that the balance of excitation and inhibition received by cortical neurons is crucial for cortical functional responses.
Article
Medicine, General & Internal
Gil Gutvirtz, Tamar Wainstock, Eyal Sheiner, Gali Pariente
Summary: Respiratory morbidity is a significant complication of prematurity, with preterm children having a higher risk of hospitalizations due to respiratory issues compared to term children. This study suggests that 30 weeks' gestation may be a critical threshold for long-term respiratory morbidity in offspring.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Roberta Giannelli, Paola Canale, Renata Del Carratore, Alessandra Falleni, Margherita Bernardeschi, Francesca Forini, Elisa Biagi, Olivia Curzio, Paolo Bongioanni
Summary: This study aimed to observe how peripheral leukocyte features change at different stages of Alzheimer's Disease (AD) to identify potential molecular markers when the first features of pathological neurodegeneration arise.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Sport Sciences
Jon Mackey, Katy Horner
Summary: Functional Threshold Power (FTP) is increasingly used in cycling for exercise prescription, especially with the rise in home trainers and virtual exercise platforms. This scoping review investigated the 20-minute FTP (FTP20) test, showing its reliability and potential use in predicting performance, but further research is needed on its relationship with other physiological markers and power-related concepts.
JOURNAL OF SPORTS SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Lukasz Przybyl, Magdalena Wozna-Wysocka, Emilia Kozlowska, Agnieszka Fiszer
Summary: Developing therapeutic strategies for HD requires the development of biomarkers for assessing treatment efficacy, with symptoms in peripheral tissues serving as indicators. Investigation of inflammatory proteins and immune cells in HD can provide insights into disease pathogenesis.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Neurosciences
Kwang-Ho Choi, Seong Jin Cho, Minji Kim, O. Sang Kwon, Suk-Yun Kang, Su Yeon Seo, Se Kyun Bang, Yeonhee Ryu
Summary: This study aimed to confirm the effect of acupuncture stimulation on acute pain from a neurological perspective by evaluating changes in somatosensory evoked potential and sensory thresholds. The results showed that direct acupuncture stimulation of the LI4 acupuncture point is more effective in treating acute pain.
FRONTIERS IN HUMAN NEUROSCIENCE
(2023)
Article
Psychology, Multidisciplinary
Amanda Cromhout, Lusilda Schutte, Marie P. Wissing, Willem D. Schutte
Summary: This study investigated the factor structure and measurement invariance of the QEWB in four culturally diverse South African samples. The one-factor structure did not fit well for the student samples, while the four-factor models showed slightly better fit. The bifactor ESEM model displayed good fit for the student samples. Configural invariance between the student samples was supported, but not metric nor scalar invariance. The use of the QEWB in the adult sample was not recommended. The results suggest the existence of a global eudaimonic well-being factor and the interrelatedness of facets of eudaimonic well-being. The influence of developmental phase on eudaimonic well-being should be explored in future.
FRONTIERS IN PSYCHOLOGY
(2022)
Review
Cardiac & Cardiovascular Systems
Joseph T. Flynn
Summary: The current criteria for diagnosing hypertension in children are not accurate enough, as emerging evidence suggests that detrimental effects of high blood pressure can occur even within the normal range according to current guidelines. Therefore, it is necessary to lower the threshold of concern for blood pressure in children and adolescents.
CIRCULATION RESEARCH
(2022)
Review
Endocrinology & Metabolism
Tim Lobstein, Jo Jewell
Summary: This paper examines the use of categories such as low and high in describing the prevalence of stunting and wasting in children under 5 years old, and proposes recommended threshold values. These categories support public health risk assessment and policy-making, aiding in monitoring global targets for overweight and obesity.
Review
Microbiology
Jingjing Cai, Suilin Chen, Feng Zhu, Xiao Lu, Taiping Liu, Wenyue Xu
Summary: Whole-parasite vaccines have regained attention due to challenges faced in developing highly efficient subunit malaria vaccines. The whole-killed blood-stage vaccine is advantageous in inducing protective immunity but raises concerns due to the high dose of parasitized red blood cell lysate required. Understanding the major components of the vaccine and developing suitable human-compatible adjuvants will be crucial for optimizing its effectiveness.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Medicine, General & Internal
Vincent Fihman, Helene Faury, Amina Moussafeur, Raphaelle Huguet, Adrien Galy, Sebastien Gallien, Pascal Lim, Raphael Lepeule, Paul-Louis Woerther
Summary: For the diagnosis of infectious endocarditis, extending the incubation time of blood culture bottles beyond five days is generally unnecessary, unless patients have risk factors for Cutibacterium acnes infection.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Biochemistry & Molecular Biology
Belay Tessema, Janine Haag, Ulrich Sack, Brigitte Koenig
Summary: Mitochondrial mass changes significantly with seasons and is negatively correlated with CSA parameters and maximal respiration. Therefore, it is recommended to determine mitochondrial mass for the correct interpretation and assessment of mitochondrial function.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Eugene A. Permyakov, Vladimir N. Uversky
Summary: This article introduces the structure, physical properties, and physiological functions of Parvalbumin (PA). Although the structure and properties of PA have been extensively studied, its physiological functions are still not well known. It is believed that PA acts as a slow calcium buffer and accelerates muscle relaxation in fast skeletal muscles. Additionally, PA may protect fast muscles from reactive oxygen species (ROS) damage and regulate calcium-dependent metabolic and electric processes in gamma-aminobutyric acid (GABA) neurons. The OM isoform of PA is thought to maintain auditory function in sensory cells.