Inherited genetic susceptibility to multiple myeloma

The CCND1 c.870G>A polymorphism is a risk factor for t(11;14)(q13;q32) multiple myeloma

(2013) Niels Weinhold et al.   NATURE GENETICS

Common variation at 3q26.2, 6p21.33, 17p11.2 and 22q13.1 influences multiple myeloma risk

(2013) Daniel Chubb et al.   NATURE GENETICS

Familial monoclonal gammopathy of undetermined significance and multiple myeloma: epidemiology, risk factors, and biological characteristics

(2012) A. J. Greenberg et al.   BLOOD

Telomere dysfunction and its role in haematological cancer

(2012) Ceri H. Jones et al.   BRITISH JOURNAL OF HAEMATOLOGY

Tumor suppressor activity of CBX7 in lung carcinogenesis

(2012) Floriana Forzati et al.   CELL CYCLE

CBX7 is a tumor suppressor in mice and humans

(2012) Floriana Forzati et al.   JOURNAL OF CLINICAL INVESTIGATION

Association of Common Variants in TNFRSF13B, TNFSF13, and ANXA3 with Serum Levels of Non-Albumin Protein and Immunoglobulin Isotypes in Japanese

(2012) Wael Osman et al.   PLoS One

Paraproteins of familial MGUS/multiple myeloma target family-typical antigens: hyperphosphorylation of autoantigens is a consistent finding in familial and sporadic MGUS/MM

(2011) S. Grass et al.   BLOOD

Personal and family history of immune-related conditions increase the risk of plasma cell disorders: a population-based study

(2011) E. K. Lindqvist et al.   BLOOD

ncRNA- and Pc2 Methylation-Dependent Gene Relocation between Nuclear Structures Mediates Gene Activation Programs

(2011) Liuqing Yang et al.   CELL

Genetic variations in multiple myeloma I: effect on risk of multiple myeloma

(2011) Annette Vangsted et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Genetic variations in multiple myeloma II: association with effect of treatment

(2011) Annette Vangsted et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

TERCpolymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres

(2011) A M Jones et al.   GUT

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma

(2011) W-J Chng et al.   LEUKEMIA

Disparities in the prevalence, pathogenesis and progression of monoclonal gammopathy of undetermined significance and multiple myeloma between blacks and whites

(2011) A J Greenberg et al.   LEUKEMIA

MyelomA Genetics International Consortium

(2011) Gareth Morgan et al.   LEUKEMIA & LYMPHOMA

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers

(2011) Siwanon Jirawatnotai et al.   NATURE

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

Common variation at 3p22.1 and 7p15.3 influences multiple myeloma risk

(2011) Peter Broderick et al.   NATURE GENETICS

Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study

(2011) Zsofia Kote-Jarai et al.   NATURE GENETICS

The prognostic significance of cytogenetics and molecular profiling in multiple myeloma

(2011) Jeffrey R. Sawyer   Cancer Genetics

Testing for rare variant associations in complex diseases

(2011) Jennifer Asimit et al.   Genome Medicine

Rare Variant Association Analysis Methods for Complex Traits

(2010) Jennifer Asimit et al.   Annual Review of Genetics

Obesity is associated with an increased risk of monoclonal gammopathy of undetermined significance among black and white women

(2010) O. Landgren et al.   BLOOD

Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs

(2010) D. D. Jima et al.   BLOOD

Gene expression profiling for molecular classification of multiple myeloma in newly diagnosed patients

(2010) A. Broyl et al.   BLOOD

Racial disparities in incidence and outcome in multiple myeloma: a population-based study

(2010) A. J. Waxman et al.   BLOOD

A polymorphism in the 3′ UTR of IRF4 linked to susceptibility and pathogenesis in chronic lymphocytic leukaemia and Hodgkin lymphoma has limited impact in multiple myeloma

(2010) Guy Pratt et al.   BRITISH JOURNAL OF HAEMATOLOGY

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

The Potential of Genes and Other Markers to Inform about Risk

(2010) M. S. Pepe et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Alternative Cyclin D1 Splice Forms Differentially Regulate the DNA Damage Response

(2010) Z. Li et al.   CANCER RESEARCH

Loss of the CBX7 protein expression correlates with a more aggressive phenotype in pancreatic cancer

(2010) Eva Karamitopoulou et al.   EUROPEAN JOURNAL OF CANCER

Oncogenic role of the chromobox protein CBX7 in gastric cancer

(2010) Xiao-Wei Zhang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Plasmablastic lymphoma with MYC translocation: evidence for a common pathway in the generation of plasmablastic features

(2010) Lekidelu Taddesse-Heath et al.   MODERN PATHOLOGY

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

(2010) Richard S Houlston et al.   NATURE GENETICS

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3)

(2010) Victor Enciso-Mora et al.   NATURE GENETICS

Common variants near TERC are associated with mean telomere length

(2010) Veryan Codd et al.   NATURE GENETICS

Genome-wide association study of hematological and biochemical traits in a Japanese population

(2010) Yoichiro Kamatani et al.   NATURE GENETICS

Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32

(2010) Lucia Conde et al.   NATURE GENETICS

Familial multiple myeloma

(2009) H. T. Lynch et al.   BLOOD

A monoclonal gammopathy precedes multiple myeloma in most patients

(2009) B. M. Weiss et al.   BLOOD

Monoclonal gammopathy of undetermined significance (MGUS) consistently precedes multiple myeloma: a prospective study

(2009) O. Landgren et al.   BLOOD

Risk of plasma cell and lymphoproliferative disorders among 14621 first-degree relatives of 4458 patients with monoclonal gammopathy of undetermined significance in Sweden

(2009) O. Landgren et al.   BLOOD

Increased risk of monoclonal gammopathy in first-degree relatives of patients with multiple myeloma or monoclonal gammopathy of undetermined significance

(2009) C. M. Vachon et al.   BLOOD

An evaluation of statistical approaches to rare variant analysis in genetic association studies

(2009) Andrew P. Morris et al.   GENETIC EPIDEMIOLOGY

Identification of DNA Methyltransferase 3a as a T Cell Receptor-Induced Regulator of Th1 and Th2 Differentiation

(2009) C. J. Gamper et al.   JOURNAL OF IMMUNOLOGY

Patterns of monoclonal gammopathy of undetermined significance and multiple myeloma in various ethnic/racial groups: support for genetic factors in pathogenesis

(2009) O Landgren et al.   LEUKEMIA

Familial myeloma and monoclonal gammopathy: A report of eight African American families

(2008) Maneesh Jain et al.   AMERICAN JOURNAL OF HEMATOLOGY

Overweight, obesity and risk of haematological malignancies: A cohort study of Swedish and Finnish twins

(2008) Karin C. Söderberg et al.   EUROPEAN JOURNAL OF CANCER

G9a and HP1 Couple Histone and DNA Methylation to TNFα Transcription Silencing during Endotoxin Tolerance

(2008) Mohamed El Gazzar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclical DNA methylation of a transcriptionally active promoter

(2008) Raphaël Métivier et al.   NATURE

Transient cyclical methylation of promoter DNA

(2008) Sara Kangaspeska et al.   NATURE

Familial Myeloma

(2008) Henry T. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

Familial Myeloma

(2008)   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA