Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements
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Title
Suppression of the let-7b microRNA pathway by DNA hypermethylation in infant acute lymphoblastic leukemia with MLL gene rearrangements
Authors
Keywords
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Journal
LEUKEMIA
Volume 27, Issue 2, Pages 389-397
Publisher
Springer Nature
Online
2012-08-24
DOI
10.1038/leu.2012.242
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Note: Only part of the references are listed.- Enforced expression of MLL-AF4 fusion in cord blood CD34+ cells enhances the hematopoietic repopulating cell function and clonogenic potential but is not sufficient to initiate leukemia
- (2011) R. Montes et al. BLOOD
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- Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting
- (2010) E. Schafer et al. BLOOD
- Thelet-7microRNA reduces tumor growth in mouse models of lung cancer
- (2010) Aurora Esquela-Kerscher et al. CELL CYCLE
- Let-7b-mediated suppression of basigin expression and metastasis in mouse melanoma cells
- (2010) Tzu-Yen Fu et al. EXPERIMENTAL CELL RESEARCH
- Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale
- (2010) D J P M Stumpel et al. LEUKEMIA
- Genetic variegation of clonal architecture and propagating cells in leukaemia
- (2010) Kristina Anderson et al. NATURE
- Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options
- (2009) D. J. P. M. Stumpel et al. BLOOD
- Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants
- (2009) R. W. Stam et al. BLOOD
- Dense Methylation of Types 1 and 2 Regulatory Regions of the CD10 Gene Promoter in Infant Acute Lymphoblastic Leukemia With MLL/AF4 Fusion Gene
- (2009) Yasuhiro Ikawa et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation
- (2009) R Ono et al. LEUKEMIA
- Hmga2 Promotes Neural Stem Cell Self-Renewal in Young but Not Old Mice by Reducing p16Ink4a and p19Arf Expression
- (2008) Jinsuke Nishino et al. CELL
- Clinical features and outcome of MLL gene rearranged acute lymphoblastic leukemia in infants with additional chromosomal abnormalities other than 11q23 translocation
- (2008) Hisamichi Tauchi et al. LEUKEMIA RESEARCH
- Suppression of non-small cell lung tumor development by the let-7 microRNA family
- (2008) M. S. Kumar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- let-7 microRNAs in development, stem cells and cancer
- (2008) Ingo Büssing et al. TRENDS IN MOLECULAR MEDICINE
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