MMSET stimulates myeloma cell growth through microRNA-mediated modulation of c-MYC

Comprehensive analysis of mammalian miRNA* species and their role in myeloid cells

(2011) F. Kuchenbauer et al.   BLOOD

miR-126 inhibits proliferation of small cell lung cancer cells by targeting SLC7A5

(2011) Edit Miko et al.   FEBS LETTERS

Future Directions of Next-Generation Novel Therapies, Combination Approaches, and the Development of Personalized Medicine in Myeloma

(2011) Constantine S. Mitsiades et al.   JOURNAL OF CLINICAL ONCOLOGY

Endothelial-specific intron-derived miR-126 is down-regulated in human breast cancer and targets both VEGFA and PIK3R2

(2011) Ni Zhu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

NSD2 Links Dimethylation of Histone H3 at Lysine 36 to Oncogenic Programming

(2011) Alex J. Kuo et al.   MOLECULAR CELL

Initial genome sequencing and analysis of multiple myeloma

(2011) Michael A. Chapman et al.   NATURE

MicroRNA-126 Inhibits SOX2 Expression and Contributes to Gastric Carcinogenesis

(2011) Takeshi Otsubo et al.   PLoS One

Impact of Host Genes and Strand Selection on miRNA and miRNA* Expression

(2011) Marta Biasiolo et al.   PLoS One

The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells

(2010) E. Martinez-Garcia et al.   BLOOD

Regulated expression of microRNAs-126/126* inhibits erythropoiesis from human embryonic stem cells

(2010) X. Huang et al.   BLOOD

IL-6-induced Enhancement of c-Myc Translation in Multiple Myeloma Cells

(2010) Yijiang Shi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression

(2010) Thian-Sze Wong et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Zebrafish microRNA-126 determines hematopoietic cell fate through c-Myb

(2010) C Grabher et al.   LEUKEMIA

Deregulation of microRNA expression in the different genetic subtypes of multiple myeloma and correlation with gene expression profiling

(2010) N C Gutiérrez et al.   LEUKEMIA

Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemia

(2010) Suman Bhatia et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Upregulated c-myc expression in multiple myeloma by internal ribosome entry results from increased interactions with and expression of PTB-1 and YB-1

(2010) L C Cobbold et al.   ONCOGENE

MicroRNAs in Cancer

(2009) Ramiro Garzon et al.   Annual Review of Medicine

Identification of microRNA expression patterns and definition of a microRNA/mRNA regulatory network in distinct molecular groups of multiple myeloma

(2009) M. Lionetti et al.   BLOOD

Biomarkers for predicting clinical responses to HDAC inhibitors

(2009) Lindsay Stimson et al.   CANCER LETTERS

Enhancing the apoptotic and therapeutic effects of HDAC inhibitors

(2009) Ailsa J. Frew et al.   CANCER LETTERS

Cytotoxicity Mediated by Histone Deacetylase Inhibitors in Cancer Cells: Mechanisms and Potential Clinical Implications

(2009) D. S. Schrump   CLINICAL CANCER RESEARCH

Epigenetic Gene Silencing by the SRY Protein Is Mediated by a KRAB-O Protein That Recruits the KAP1 Co-repressor Machinery

(2009) Hongzhuang Peng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blimp-1/Prdm1 Alternative Promoter Usage during Mouse Development and Plasma Cell Differentiation

(2009) M. A. J. Morgan et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetics in cancer: Targeting chromatin modifications

(2009) L. Ellis et al.   MOLECULAR CANCER THERAPEUTICS

A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf–Hirschhorn syndrome

(2009) Keisuke Nimura et al.   NATURE

Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration

(2009) X Li et al.   ONCOGENE

MMSET deregulation affects cell cycle progression and adhesion regulons in t(4;14) myeloma plasma cells

(2008) J. L.R. Brito et al.   HAEMATOLOGICA

MYCtranslocation-negative classical Burkitt lymphoma cases: an alternative pathogenetic mechanism involving miRNA deregulation

(2008) E Leucci et al.   JOURNAL OF PATHOLOGY

MiRNAs, epigenetics, and cancer

(2008) Arefeh Rouhi et al.   MAMMALIAN GENOME

Multiple Myeloma-Related WHSC1/MMSET Isoform RE-IIBP Is a Histone Methyltransferase with Transcriptional Repression Activity

(2008) J.-Y. Kim et al.   MOLECULAR AND CELLULAR BIOLOGY

IRF4 addiction in multiple myeloma

(2008) Arthur L. Shaffer et al.   NATURE

Putting a KAP on Transcription and Stress

(2008) Mark D. Alter et al.   NEURON

MicroRNAs regulate critical genes associated with multiple myeloma pathogenesis

(2008) F. Pichiorri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct microRNA expression profiles in acute myeloid leukemia with common translocations

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Pathologic Link between Wilms Tumor Suppressor Gene, WT1, and IFI16

(2008) Marianne K-H. Kim et al.   NEOPLASIA

The MMSET protein is a histone methyltransferase with characteristics of a transcriptional corepressor

(2007) J. Marango et al.   BLOOD