Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis
Published 2012 View Full Article
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Title
Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis
Authors
Keywords
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Journal
LEUKEMIA
Volume 26, Issue 7, Pages 1537-1546
Publisher
Springer Nature
Online
2012-02-10
DOI
10.1038/leu.2012.38
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Note: Only part of the references are listed.- Two types of C/EBP mutations play distinct but collaborative roles in leukemogenesis: lessons from clinical data and BMT models
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- Heterogeneity within AML with CEBPA mutations; only CEBPA double mutations, but not single CEBPA mutations are associated with favourable prognosis
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- Hematopoietic Stem Cell Expansion Precedes the Generation of Committed Myeloid Leukemia-Initiating Cells in C/EBPα Mutant AML
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- Antiangiogenic drugs in ovarian cancer
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- Microenvironment Determines Lineage Fate in a Human Model of MLL-AF9 Leukemia
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- Modeling of C/EBPα Mutant Acute Myeloid Leukemia Reveals a Common Expression Signature of Committed Myeloid Leukemia-Initiating Cells
- (2008) Peggy Kirstetter et al. CANCER CELL
- Somatic CEBPA Mutations Are a Frequent Second Event in Families With Germline CEBPA Mutations and Familial Acute Myeloid Leukemia
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- Dysregulation of the C/EBPα Differentiation Pathway in Human Cancer
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- C/EBPα or C/EBPα oncoproteins regulate the intrinsic and extrinsic apoptotic pathways by direct interaction with NF-κB p50 bound to the bcl-2 and FLIP gene promoters
- (2008) I Paz-Priel et al. LEUKEMIA
- Investigation of C/EBPα function in human (versus murine) myelopoiesis provides novel insight into the impact of CEBPA mutations in acute myelogenous leukemia (AML)
- (2008) B Niebuhr et al. LEUKEMIA
- Another pedigree with familial acute myeloid leukemia and germline CEBPA mutation
- (2008) A Renneville et al. LEUKEMIA
- Mutations and Treatment Outcome in Cytogenetically Normal Acute Myeloid Leukemia
- (2008) Richard F. Schlenk et al. NEW ENGLAND JOURNAL OF MEDICINE
- Initiating and Cancer-Propagating Cells in TEL-AML1-Associated Childhood Leukemia
- (2008) D. Hong et al. SCIENCE
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