NKL homeobox genes in leukemia

CpG island methylation profiling in human salivary gland adenoid cystic carcinoma

(2011) Achim Bell et al.   CANCER

Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia

(2011) Irene Homminga et al.   CANCER CELL

Densely Interconnected Transcriptional Circuits Control Cell States in Human Hematopoiesis

(2011) Noa Novershtern et al.   CELL

VentXtrans-Activates p53 and p16ink4ato Regulate Cellular Senescence

(2011) Xiaoming Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppression of lung adenocarcinoma progression by Nkx2-1

(2011) Monte M. Winslow et al.   NATURE

Quantitative DNA methylation analysis detects cervical intraepithelial neoplasms type 3 and worse

(2010) Hung-Cheng Lai et al.   CANCER

The c.469+46_56del mutation in the homeobox MSX1 gene—A novel risk factor in breast cancer?

(2010) Tomasz Sliwinski et al.   Cancer Epidemiology

Upregulation of DLX5 Promotes Ovarian Cancer Cell Proliferation by Enhancing IRS-2-AKT Signaling

(2010) Y. Tan et al.   CANCER RESEARCH

CpG Island Hypermethylation in Human Astrocytomas

(2010) Xiwei Wu et al.   CANCER RESEARCH

Evaluation of MSX2 mRNA in brush cytology specimens distinguished pancreatic carcinoma from chronic pancreatitis

(2010) Kennichi Satoh et al.   CANCER SCIENCE

Both Gene Amplification and Allelic Loss Occur at 14q13.3 in Lung Cancer

(2010) T. Harris et al.   CLINICAL CANCER RESEARCH

Conservation of gene linkage in dispersed vertebrate NK homeobox clusters

(2010) Karl R. Wotton et al.   DEVELOPMENT GENES AND EVOLUTION

Epigenetic analysis of childhood acute lymphoblastic leukemia

(2010) Thomas L. Dunwell et al.   Epigenetics

Genome-wide DNA methylation profiling of chronic lymphocytic leukemia allows identification of epigenetically repressed molecular pathways with clinical impact

(2010) Wei-Gang Tong et al.   Epigenetics

Detection of differential mitotic cell age in bone marrow CD34+ cells from patients with myelodysplastic syndrome and acute leukemia by analysis of an epigenetic molecular clock DNA signature

(2010) Maximilian Mossner et al.   EXPERIMENTAL HEMATOLOGY

NKX3.1is a direct TAL1 target gene that mediates proliferation of TAL1-expressing human T cell acute lymphoblastic leukemia

(2010) Sophie Kusy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Expression of MSX2 predicts malignancy of branch duct intraductal papillary mucinous neoplasm of the pancreas

(2010) Kennichi Satoh et al.   JOURNAL OF GASTROENTEROLOGY

TLX1 and NOTCH coregulate transcription in T cell acute lymphoblastic leukemia cells

(2010) Irene Riz et al.   Molecular Cancer

DNA methylation patterns in luminal breast cancers differ from non-luminal subtypes and can identify relapse risk independent of other clinical variables

(2010) Sitharthan Kamalakaran et al.   Molecular Oncology

Genome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemia

(2010) Konstantinos J. Mavrakis et al.   NATURE CELL BIOLOGY

The TLX1 oncogene drives aneuploidy in T cell transformation

(2010) Kim De Keersmaecker et al.   NATURE MEDICINE

EMX2 is epigenetically silenced and suppresses growth in human lung cancer

(2010) J Okamoto et al.   ONCOGENE

The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia

(2010) V. P. S. Rawat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Lmo2 Oncogene Initiates Leukemia in Mice by Inducing Thymocyte Self-Renewal

(2010) M. P. McCormack et al.   SCIENCE

Transcriptional activation by TLX1/HOX11 involves Gro/TLE corepressors

(2009) Irene Riz et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

(2009) D. J. P. M. Stumpel et al.   BLOOD

NK-like homeodomain proteins activate NOTCH3-signaling in leukemic T-cells

(2009) Stefan Nagel et al.   BMC CANCER

Role ofTLX1in T-cell acute lymphoblastic leukaemia pathogenesis

(2009) Irene Riz et al.   BRITISH JOURNAL OF HAEMATOLOGY

DNMT1 and DNMT3B Modulate Distinct Polycomb-Mediated Histone Modifications in Colon Cancer

(2009) B. Jin et al.   CANCER RESEARCH

VentX, a Novel Lymphoid-Enhancing Factor/T-Cell Factor-Associated Transcription Repressor, Is a Putative Tumor Suppressor

(2009) H. Gao et al.   CANCER RESEARCH

A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression

(2009) M. Yu et al.   GENES & DEVELOPMENT

Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia

(2009) Elaine Coustan-Smith et al.   LANCET ONCOLOGY

Activation of miR-17-92 by NK-like homeodomain proteins suppresses apoptosis via reduction of E2F1 in T-cell acute lymphoblastic leukemia

(2009) Stefan Nagel et al.   LEUKEMIA & LYMPHOMA

CpG island methylation profiling in human melanoma cell lines

(2009) Carmen S. Tellez et al.   MELANOMA RESEARCH

Dissection of the Transformation of Primary Human Hematopoietic Cells by the Oncogene NUP98-HOXA9

(2009) Enas R. Yassin et al.   PLoS One

Up-Regulation of MSX2 Enhances the Malignant Phenotype and Is Associated with Twist 1 Expression in Human Pancreatic Cancer Cells

(2008) Kennichi Satoh et al.   AMERICAN JOURNAL OF PATHOLOGY

The PRH/Hex repressor protein causes nuclear retention of Groucho/TLE co-repressors

(2008) Cecile Desjobert et al.   BIOCHEMICAL JOURNAL

Leukemogenic mechanisms and targets of a NUP98/HHEX fusion in acute myeloid leukemia

(2008) D. Jankovic et al.   BLOOD

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

(2008) P. Van Vlierberghe et al.   BLOOD

Loss of TLE1 and TLE4 from the del(9q) commonly deleted region in AML cooperates with AML1-ETO to affect myeloid cell proliferation and survival

(2008) F. Dayyani et al.   BLOOD

Amplification of the BP1 homeobox gene in breast cancer

(2008) Luciane R. Cavalli et al.   CANCER GENETICS AND CYTOGENETICS

Epigenetic Inactivation of the Groucho Homologue Gene TLE1 in Hematologic Malignancies

(2008) M. F. Fraga et al.   CANCER RESEARCH

Prognostic significance of BP1 mRNA expression level in patients with non-small cell lung cancer

(2008) Man Yu et al.   CLINICAL BIOCHEMISTRY

Activation of Placenta-Specific Transcription Factor Distal-less Homeobox 5 Predicts Clinical Outcome in Primary Lung Cancer Patients

(2008) T. Kato et al.   CLINICAL CANCER RESEARCH

Grappling with the HOX network in hematopoiesis and leukemia

(2008) Glenda et al.   Frontiers in Bioscience-Landmark

Transcriptional activation of the cardiac homeobox gene CSX1/NKX2-5 in a B-cell chronic lymphoproliferative disorder

(2008) X. Su et al.   HAEMATOLOGICA

Identification of novel DNA methylation markers in cervical cancer

(2008) Hung-Cheng Lai et al.   INTERNATIONAL JOURNAL OF CANCER

Genome-wide identification of aberrantly methylated promoter associated CpG islands in acute lymphocytic leukemia

(2008) S-Q Kuang et al.   LEUKEMIA

Thymic adult T-cell acute lymphoblastic leukemia stratified in standard- and high-risk group by aberrant HOX11L2 expression: experience of the German multicenter ALL study group

(2008) U Baak et al.   LEUKEMIA

Cooperative genetic defects in TLX3 rearranged pediatric T-ALL

(2008) P Van Vlierberghe et al.   LEUKEMIA

BP1, a homeoprotein, is significantly expressed in prostate adenocarcinoma and is concordant with prostatic intraepithelial neoplasia

(2008) Arnold M Schwartz et al.   MODERN PATHOLOGY

Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas

(2008) Justyna Leja et al.   MODERN PATHOLOGY

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer

(2008) K A Kwei et al.   ONCOGENE

Establishment and Characterization of an Ovarian Yolk Sac Tumor Cell Line Reveals Possible Involvement of Nkx2.5 in Tumor Development

(2008) Kiyosumi Shibata et al.   ONCOLOGY

Transcriptional regulation of FHL1 by TLX1/HOX11 is dosage, cell-type and promoter context-dependent

(2007) Kim L. Rice et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS