Constitutive activation of STAT3 in Sézary syndrome is independent of SHP-1

Sezary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

(2010) J. J. Campbell et al.   BLOOD

Activity of deacetylase inhibitor panobinostat (LBH589) in cutaneous T-cell lymphoma models: Defining molecular mechanisms of resistance

(2010) Wenlin Shao et al.   INTERNATIONAL JOURNAL OF CANCER

Absence of gain-of-function JAK1 and JAK3 mutations in adult T cell leukemia/lymphoma

(2010) T. Kameda et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Survival Outcomes and Prognostic Factors in Mycosis Fungoides/Sézary Syndrome: Validation of the Revised International Society for Cutaneous Lymphomas/European Organisation for Research and Treatment of Cancer Staging Proposal

(2010) Nita Sally Agar et al.   JOURNAL OF CLINICAL ONCOLOGY

Curcumin Selectively Induces Apoptosis in Cutaneous T-Cell Lymphoma Cell Lines and Patients’ PBMCs: Potential Role for STAT-3 and NF-κB Signaling

(2010) Chunlei Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Multi-Step Aberrant CpG Island Hyper-Methylation Is Associated with the Progression of Adult T–Cell Leukemia/Lymphoma

(2009) Hiaki Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Constitutive JAK3 activation induces lymphoproliferative syndromes in murine bone marrow transplantation models

(2009) M. G. Cornejo et al.   BLOOD

HSP90 is essential for Jak-STAT signaling in classical Hodgkin lymphoma cells

(2009) Nils Schoof et al.   Cell Communication and Signaling

Janus kinases in immune cell signaling

(2009) Kamran Ghoreschi et al.   IMMUNOLOGICAL REVIEWS

JAK3: A two-faced player in hematological disorders

(2009) Melanie G. Cornejo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Downregulation of Fas Gene Expression in Sézary Syndrome Is Associated with Promoter Hypermethylation

(2009) Christine L. Jones et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

JAK mutations in high-risk childhood acute lymphoblastic leukemia

(2009) C. G. Mullighan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Resistance to FasL and tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis in Sezary syndrome T-cells associated with impaired death receptor and FLICE-inhibitory protein expression

(2008) E. Contassot et al.   BLOOD

STAT3 as a target for inducing apoptosis in solid and hematological tumors

(2008) Khandaker Al Zaid Siddiquee et al.   CELL RESEARCH

Roles of unphosphorylated STATs in signaling

(2008) Jinbo Yang et al.   CELL RESEARCH

Immune Function Abnormalities in Peripheral Blood Mononuclear Cell Cytokine Expression Differentiates Stages of Cutaneous T-Cell Lymphoma/Mycosis Fungoides

(2008) B. F. Chong et al.   CLINICAL CANCER RESEARCH

Somatically acquiredJAK1mutations in adult acute lymphoblastic leukemia

(2008) Elisabetta Flex et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Avicin D Selectively Induces Apoptosis and Downregulates p-STAT-3, bcl-2, and Survivin in Cutaneous T-Cell Lymphoma Cells

(2008) Chunlei Zhang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Cucurbitacin I Inhibits Stat3 and Induces Apoptosis in Sézary Cells

(2008) Marloes S. van Kester et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Mining for JAK–STAT mutations in cancer

(2008) Stefan N. Constantinescu et al.   TRENDS IN BIOCHEMICAL SCIENCES

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY