Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts
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Title
Silencing of ETV6/RUNX1 abrogates PI3K/AKT/mTOR signaling and impairs reconstitution of leukemia in xenografts
Authors
Keywords
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Journal
LEUKEMIA
Volume 26, Issue 5, Pages 927-933
Publisher
Springer Nature
Online
2011-11-18
DOI
10.1038/leu.2011.322
References
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- Targeting survival cascades induced by activation of Ras/Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways for effective leukemia therapy
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- Gene array analysis reveals a common Runx transcriptional programme controlling cell adhesion and survival
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