Connectivity mapping identifies HDAC inhibitors for the treatment of t(4;11)-positive infant acute lymphoblastic leukemia

MLL-aberrant leukemia: complete cytogenetic remission following treatment with a histone deacetylase inhibitor (HDACi)

(2010) Kate L. Burbury et al.   ANNALS OF HEMATOLOGY

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

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Leukemogenic transformation by HOXA cluster genes

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Promoter hypermethylation in MLL-r infant acute lymphoblastic leukemia: biology and therapeutic targeting

(2010) E. Schafer et al.   BLOOD

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis

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Ubiquitylation of the amino terminus of Myc by SCFβ-TrCP antagonizes SCFFbw7-mediated turnover

(2010) Nikita Popov et al.   NATURE CELL BIOLOGY

Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options

(2009) D. J. P. M. Stumpel et al.   BLOOD

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

(2009) R. W. Stam et al.   BLOOD

Phase II Multi-Institutional Trial of the Histone Deacetylase Inhibitor Romidepsin As Monotherapy for Patients With Cutaneous T-Cell Lymphoma

(2009) Richard L. Piekarz et al.   JOURNAL OF CLINICAL ONCOLOGY

New insights to the MLL recombinome of acute leukemias

(2009) C Meyer et al.   LEUKEMIA

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Infant acute lymphoblastic leukemia: Lessons learned and future directions

(2009) Rob Pieters   Current Hematologic Malignancy Reports

Expression and role of DJ-1 in leukemia

(2008) Hang Liu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

(2008) Andrei V. Krivtsov et al.   CANCER CELL

The GTPase Ran: regulation of cell life and potential roles in cell transformation

(2008) Wilhelmina et al.   Frontiers in Bioscience-Landmark

Aberrant chromatin at genes encoding stem cell regulators in human mixed-lineage leukemia

(2008) M. G. Guenther et al.   GENES & DEVELOPMENT

Acute lymphoblastic leukaemia

(2008) Ching-Hon Pui et al.   LANCET

Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARα

(2007) Oliver H. Krämer et al.   FASEB JOURNAL