ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1

B-Lineage Differentiation Stages Resolved by Multiparameter Flow Cytometry

(2010) RICHARD R. HARDY et al.   Annals of the New York Academy of Sciences

BCR-ABL SH3-SH2 domain mutations in chronic myeloid leukemia patients on imatinib

(2010) D. W. Sherbenou et al.   BLOOD

Wnt/Ca2+/NFAT Signaling Maintains Survival of Ph+ Leukemia Cells upon Inhibition of Bcr-Abl

(2010) Mark A. Gregory et al.   CANCER CELL

The B Cell Mutator AID Promotes B Lymphoid Blast Crisis and Drug Resistance in Chronic Myeloid Leukemia

(2009) Lars Klemm et al.   CANCER CELL

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

(2009) Thomas O'Hare et al.   CANCER CELL

Cell Proliferation and Epidermal Growth Factor Signaling in Non-small Cell Lung Adenocarcinoma Cell Lines Are Dependent on Rin1

(2009) Jin C. Tomshine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated expression of the Ras effector Rin1 in forebrain neurons

(2009) Bartholomew Dzudzor et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Hedgehog signalling is essential for maintenance of cancer stem cells in myeloid leukaemia

(2009) Chen Zhao et al.   NATURE

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

(2008) Christine Dierks et al.   CANCER CELL

Genetic and Epigenetic Silencing of MicroRNA-203 Enhances ABL1 and BCR-ABL1 Oncogene Expression

(2008) María J. Bueno et al.   CANCER CELL

Enhancement of ABL Kinase Catalytic Efficiency by a Direct Binding Regulator Is Independent of Other Regulatory Mechanisms

(2008) Xiaoqing Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tyrosine Phosphorylation in the SH3 Domain Disrupts Negative Regulatory Interactions within the c-Abl Kinase Core

(2008) Shugui Chen et al.   JOURNAL OF MOLECULAR BIOLOGY

Disruption of the Bcr-Abl/Hsp90 protein complex: a possible mechanism to inhibit Bcr-Abl-positive human leukemic blasts by novobiocin

(2008) L X Wu et al.   LEUKEMIA