Insights into the cellular origin and etiology of the infant pro-B acute lymphoblastic leukemia with MLL-AF4 rearrangement

The AF4{middle dot}MLL fusion protein is capable of inducing ALL in mice without requirement of MLL{middle dot}AF4

(2010) A. Bursen et al.   BLOOD

iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability

(2010) Veronica Ramos-Mejia et al.   CELL RESEARCH

Leukemia-associated genetic aberrations in mesenchymal stem cells of children with acute lymphoblastic leukemia

(2010) Shabnam Shalapour et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Where do the leukaemia relapses come from?

(2010) Arndt Borkhardt   JOURNAL OF MOLECULAR MEDICINE-JMM

Nodal/Activin Signaling Predicts Human Pluripotent Stem Cell Lines Prone to Differentiate Toward the Hematopoietic Lineage

(2010) Veronica Ramos-Mejia et al.   MOLECULAR THERAPY

The ROCK Inhibitor Y-27632 Negatively Affects the Expansion/Survival of Both Fresh and Cryopreserved Cord Blood-Derived CD34+ Hematopoietic Progenitor Cells

(2010) Clara Bueno et al.   Stem Cell Reviews and Reports

Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection

(2010) Ivan Gutierrez-Aranda et al.   STEM CELLS

Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants

(2009) R. W. Stam et al.   BLOOD

Etoposide induces MLL rearrangements and other chromosomal abnormalities in human embryonic stem cells

(2009) Clara Bueno et al.   CARCINOGENESIS

Feeder-free maintenance of hESCs in mesenchymal stem cell-conditioned media: distinct requirements for TGF-β and IGF-II

(2009) Rosa Montes et al.   CELL RESEARCH

Intra-bone marrow transplantation of human CD34+ cells into NOD/LtSz-scid IL-2rγnull mice permits multilineage engraftment without previous irradiation

(2009) Clara Bueno et al.   CYTOTHERAPY

Mesenchymal stem cells facilitate the derivation of human embryonic stem cells from cryopreserved poor-quality embryos

(2009) J.L. Cortes et al.   HUMAN REPRODUCTION

Bone marrow mesenchymal stem cells from infants with MLL-AF4+acute leukemia harbor and express the MLL-AF4 fusion gene

(2009) Pablo Menendez et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4

(2009) M Bardini et al.   LEUKEMIA

Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q− syndrome

(2009) O Lopez-Villar et al.   LEUKEMIA

Standardized MRD quantification in European ALL trials: Proceedings of the Second International Symposium on MRD assessment in Kiel, Germany, 18–20 September 2008

(2009) M Brüggemann et al.   LEUKEMIA

Etoposide-initiatedMLLrearrangements detected at high frequency in human primitive hematopoietic stem cells within vitroandin vivolong-term repopulating potential

(2008) Jolanta Libura et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease

(2008) C. R. Walkley et al.   GENES & DEVELOPMENT

NG2 antigen is expressed in CD34+ HPCs and plasmacytoid dendritic cell precursors: is NG2 expression in leukemia dependent on the target cell where leukemogenesis is triggered?

(2008) C Bueno et al.   LEUKEMIA

The immunophenotype of different immature, myeloid and B-cell lineage-committed CD34+ hematopoietic cells allows discrimination between normal/reactive and myelodysplastic syndrome precursors

(2008) S Matarraz et al.   LEUKEMIA

Human ESCs predisposition to karyotypic instability: Is a matter of culture adaptation or differential vulnerability among hESC lines due to inherent properties?

(2008) Puri Catalina et al.   Molecular Cancer

Whole-Blastocyst Culture Followed by Laser Drilling Technology Enhances the Efficiency of ICM Isolation and ESC Derivation from Good- and Poor-Quality Mouse Embryos: New Insights for Derivation of hESC Lines

(2008) J.L. Cortes et al.   STEM CELLS AND DEVELOPMENT

Electron Microscopy Reveals the Presence of Viruses in Mouse Embryonic Fibroblasts But Neither in Human Embryonic Fibroblasts Nor in Human Mesenchymal Cells Used for hESC Maintenance: Toward an Implementation of Microbiological Quality Assurance Program in Stem Cell Banks

(2008) Fernando Cobo et al.   Cloning Stem Cells