Combining carbon ion irradiation and non-homologous end-joining repair inhibitor NU7026 efficiently kills cancer cells

The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis

(2015) Nicholas Jette et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

The Major DNA Repair Pathway after Both Proton and Carbon-Ion Radiation is NHEJ, but the HR Pathway is More Relevant in Carbon Ions

(2015) Ariungerel Gerelchuluun et al.   RADIATION RESEARCH

Differential DNA repair pathway choice in cancer cells after proton- and photon-irradiation

(2015) Andrea O. Fontana et al.   RADIOTHERAPY AND ONCOLOGY

DAB2IP Regulates Autophagy in Prostate Cancer in Response to Combined Treatment of Radiation and a DNA-PKcs Inhibitor

(2015) Lan Yu et al.   NEOPLASIA

Suppression of DNA-dependent protein kinase sensitize cells to radiation without affecting DSB repair

(2014) Ann-Sofie Gustafsson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Nonhomologous End-Joining Repair Plays a More Important Role than Homologous Recombination Repair in Defining Radiosensitivity after Exposure to High-LET Radiation

(2014) Akihisa Takahashi et al.   RADIATION RESEARCH

DNA-PK inhibition by NU7441 sensitizes breast cancer cells to ionizing radiation and doxorubicin

(2013) Wojciech M. Ciszewski et al.   BREAST CANCER RESEARCH AND TREATMENT

Detection and Repair of Ionizing Radiation-Induced DNA Double Strand Breaks: New Developments in Nonhomologous End Joining

(2013) Chen Wang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Misrepair of DNA double-strand breaks after exposure to heavy-ion beams causes a peak in the LET–RBE relationship with respect to cell killing in DT40 cells

(2013) Mizuho Aoki-Nakano et al.   JOURNAL OF RADIATION RESEARCH

DNA-PKcs Inhibition Sensitizes Cancer Cells to Carbon-Ion Irradiation via Telomere Capping Disruption

(2013) Xin Zhou et al.   PLoS One

Particle radiotherapy with carbon ion beams

(2013) Tatsuya Ohno   EPMA Journal

Role of non-homologous end joining in V(D)J recombination

(2012) Shruti Malu et al.   IMMUNOLOGIC RESEARCH

A Review of Update Clinical Results of Carbon Ion Radiotherapy

(2012) H. Tsujii et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Playing the End Game: DNA Double-Strand Break Repair Pathway Choice

(2012) J. Ross Chapman et al.   MOLECULAR CELL

Inhibition of Non-Homologous End Joining Repair Impairs Pancreatic Cancer Growth and Enhances Radiation Response

(2012) Ying-Hua Li et al.   PLoS One

A Stochastic Model of DNA Fragments Rejoining

(2012) Yongfeng Li et al.   PLoS One

Factors determining DNA double-strand break repair pathway choice in G2 phase

(2011) Atsushi Shibata et al.   EMBO JOURNAL

Inhibition of DNA-Dependent Protein Kinase Induces Accelerated Senescence in Irradiated Human Cancer Cells

(2011) A. Azad et al.   MOLECULAR CANCER RESEARCH

Targeting the DNA Double Strand Break Repair Machinery in Prostate Cancer

(2011) Fadhel S. Shaheen et al.   PLoS One

Unrepaired clustered DNA lesions induce chromosome breakage in human cells

(2011) A. Asaithamby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of homologous recombination in radiation-induced double-strand break repair

(2011) Penny A. Jeggo et al.   RADIOTHERAPY AND ONCOLOGY

Carbon Ion Radiotherapy at the Gunma University Heavy Ion Medical Center: New Facility Set-up

(2011) Tatsuya Ohno et al.   Cancers

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Characteristics of DNA-binding proteins determine the biological sensitivity to high-linear energy transfer radiation

(2010) H. Wang et al.   NUCLEIC ACIDS RESEARCH

Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair

(2009) E. Bolderson et al.   CLINICAL CANCER RESEARCH

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

DNA double-strand breaks: Their production, recognition, and repair in eukaryotes

(2009) Takeo Ohnishi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Charged particles in radiation oncology

(2009) Marco Durante et al.   Nature Reviews Clinical Oncology

The Ku-dependent non-homologous end-joining but not other repair pathway is inhibited by high linear energy transfer ionizing radiation

(2008) Hongyan Wang et al.   DNA REPAIR

DNA Damage Recognition Proteins Localize along Heavy Ion Induced Tracks in the Cell Nucleus

(2008) Akihisa TAKAHASHI et al.   JOURNAL OF RADIATION RESEARCH

Quantitative Analysis of Isolated and Clustered DNA Damage Induced by Gamma-rays, Carbon Ion Beams, and Iron Ion Beams

(2008) Hiroaki TERATO et al.   JOURNAL OF RADIATION RESEARCH