Article
Physiology
Yukun Jiang, Yuzhe Guan, Yuanchen Lan, Shuo Chen, Tiancheng Li, Shujuan Zou, Zhiai Hu, Qingsong Ye
Summary: The Piezo1 channel plays a critical role in mediating bone formation and osteoclastic activities during orthodontic tooth movement, particularly on the tension side. Inhibition of Piezo1 function leads to reduced expression of osteogenesis-associated transcription factors and disruptions in bone remodeling processes.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Biotechnology & Applied Microbiology
Jie Zhou, Yanlin Zhu, Dongqing Ai, Mengjiao Zhou, Han Li, Yiru Fu, Jinlin Song
Summary: Low-intensity pulsed ultrasound (LIPUS) can improve orthodontic tooth movement and alveolar bone remodeling by promoting the interaction between osteoblasts and osteoclasts, thus enhancing the effectiveness of orthodontic treatment.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Dentistry, Oral Surgery & Medicine
Yugui Du, Kai Yang
Summary: Objective: This study aimed to investigate the role of Piezo1 in alveolar bone remodeling during orthodontic tooth movement (OTM). The results suggest that Piezo1 plays a crucial role in alveolar bone remodeling during OTM, and the Wnt/Ca2+ signaling pathway may be involved in this process.
ARCHIVES OF ORAL BIOLOGY
(2023)
Article
Multidisciplinary Sciences
Sharmin Sultana, Norma Ab Rahman, Siti Lailatul Akmar Zainuddin, Basaruddin Ahmad
Summary: This clinical trial compared the time required to complete the levelling and alignment stage in severe maxillary malocclusion cases with premolar extraction using the flapless piezocision procedure. The study found that the piezocision group had a significantly shorter time to complete the levelling and alignment stage compared to the control group. The piezocision group also experienced greater reduction in irregularity index and faster alignment rate.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Taisuke Yamauchi, Megumi Miyabe, Nobuhisa Nakamura, Mizuho Ito, Takeo Sekiya, Saki Kanada, Rina Hoshino, Tatsuaki Matsubara, Ken Miyazawa, Shigemi Goto, Keiko Naruse
Summary: This study investigated the effects of glucose-dependent insulinotropic polypeptide (GIP) on force-induced bone remodeling during orthodontic tooth movement. The results suggest that GIP promotes osteoblast formation and suppresses osteoclasts in force-induced bone remodeling.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Cell Biology
Shuainan Wu, Jianqi Wang, Lu Liu, Ying Pang, Zhaobao Li, Hong Mu
Summary: Patients with periodontitis have a higher risk of alveolar bone loss during orthodontic therapy. Irisin promotes cell proliferation and osteogenic differentiation, and increases the expression of beneficial factors while decreasing detrimental factors in periodontal ligament stem cells. In rats with periodontitis and orthodontic tooth movement, irisin ameliorates alveolar bone loss and inflammation, and enhances the expression ratio of beneficial factors. Overall, irisin prevents alveolar bone destruction during orthodontic tooth movement in rats with periodontitis.
Review
Biochemistry & Molecular Biology
Sinan Sen, Ralf Erber
Summary: During orthodontic tooth movement, neuronal guidance molecules (NGMs), particularly Semaphorins, ephrins, and Eph receptors, have been identified to play important roles in bone remodeling. However, research on the functions of NGMs during orthodontic tooth movement is currently limited, and further studies are needed to fully understand their significance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Dentistry, Oral Surgery & Medicine
Junyi Zheng, Kai Yang
Summary: The study showed that low-level laser therapy can accelerate orthodontic tooth movement and alter the levels of IL-1 beta, RANKL, and OPG in gingival crevicular fluid under specific parameter settings.
Review
Dentistry, Oral Surgery & Medicine
Dimitrios Michelogiannakis, Luay Jabr, Abdul Basir Barmak, Paul Emile Rossouw, Elli Anna Kotsailidi, Fawad Javed
Summary: The influence of low-level-laser therapy (LLLT) on the stability of orthodontic mini-screw implants (MSIs) was systematically reviewed. The meta-analyses of randomized controlled clinical trials (RCTs) showed that LLLT treatment significantly improved MSI stability compared to untreated MSIs, regardless of the measurement method used. However, due to the limited number of studies and other limitations, further research is needed to confirm these findings.
EUROPEAN JOURNAL OF ORTHODONTICS
(2022)
Article
Materials Science, Multidisciplinary
Ruojing Liu, Li Huang, Xiaoyue Xiao, Yuzhe Guan, Yukun Jiang, Xing Yin, Shujuan Zou, Qingsong Ye
Summary: Corticotomy is an effective method to accelerate orthodontic tooth movement by promoting bone turnover and tissue remodeling. In a mouse model study, it was found that corticotomy can accelerate tooth movement by promoting osteogenic and proliferative activity, and eliminating root resorption through upregulating the Wnt signal pathway.
Article
Dentistry, Oral Surgery & Medicine
Andressa V. B. Nogueira, Camila C. Marcantonio, Rafael S. de Molon, Natalia D. P. Leguizamon, Renata C. L. Silva, James Deschner, Paulo S. Cerri, Joni A. Cirelli
Summary: The present study compared two different models of orthodontic tooth movement (OTM) in rats and found that the occlusal appliance (OA) group had little or no deleterious effect on periodontal tissues compared to the ligature appliance (LA) group, suggesting its use may be more reliable for OTM induction in rats for 15 days.
ARCHIVES OF ORAL BIOLOGY
(2021)
Review
Chemistry, Multidisciplinary
Francesco Inchingolo, Angelo Michele Inchingolo, Giulia Latini, Gaetano Del Vecchio, Irma Trilli, Laura Ferrante, Gianna Dipalma, Andrea Palermo, Alessio Danilo Inchingolo
Summary: This review provides an overview of recent research on the potential of low-level light therapy (LLLT) in orthodontics, focusing on tooth movement, root resorption, pain perception, and miniscrew stability. LLLT has shown positive effects on osteoblast proliferation, bone regeneration, and increased tooth movement rate, as well as improving miniscrew stability and reducing root resorption. However, the potential benefits of LLLT in pain relief during orthodontic treatment remain controversial. Further studies are needed to determine its efficacy in pain management.
APPLIED SCIENCES-BASEL
(2023)
Article
Cell Biology
Mingrui Zhai, Shuyue Cui, Lan Li, Chen Cheng, Zijie Zhang, Jiani Liu, Fulan Wei
Summary: Lactate can respond to mechanical stimulus during orthodontic tooth movement and has an impact on the alveolar bone remodeling. The regulatory effects of lactate are mediated by histone lactylation. Lactate is a critical modulator for alveolar bone remodeling during orthodontics.
Article
Engineering, Biomedical
Delong Jiao, Jing Wang, Wenting Yu, Ke Zhang, Ning Zhang, Lingyan Cao, Xinquan Jiang, Yuxing Bai
Summary: This study evaluated the use of biocompatible gelatin reduced graphene oxide (GOG) to accelerate orthodontic tooth movement. The in vivo experiments on a mouse model showed that GOG injection promoted bone resorption and neovascularization, resulting in accelerated tooth movement. In vitro experiments demonstrated the good biocompatibility of GOG in bone marrow stromal stem cells (BMSCs) and confirmed that GOG injection did not affect the survival and life of animals. Furthermore, the study found that GOG-stimulated BMSCs regulated osteoclastogenesis and angiogenesis, with the PERK pathway playing an important role.
BIOACTIVE MATERIALS
(2022)
Article
Multidisciplinary Sciences
Hosam Ali Baeshen
Summary: This study compared cytokine, cellular marker analysis, and defensin levels in saliva samples from individuals undergoing orthodontic treatment with lingual and labial appliances. Significant differences were found in levels of CCL2, IL-17A, and IL-6, as well as in cellular markers and defensin levels between the two groups. Overall, subjects with lingual appliances showed higher levels of certain proteins and cells, but lower defensin levels compared to those with labial appliances. The study suggests the potential for innovative methods to improve orthodontic treatments in the future.
Article
Engineering, Biomedical
Farhad Sobouti, Nasim Chiniforush, Hamid Jaahed Saravani, Mohammad Noroozian, Mark Cronshaw, Reza Alizadeh Navaei, Vahid Rakhshan, Sepideh Dadgar
Summary: The study showed that the combination of compound topical anesthetic and photobiomodulation therapy provided adequate local anesthesia for the placement of miniscrews in the buccal side of the maxillary bone during the procedure and effectively reduced postoperative pain levels.
LASERS IN MEDICAL SCIENCE
(2022)
Review
Biochemistry & Molecular Biology
Rojin Shahmohammadi, Shima Younespour, Mojgan Paknejad, Nasim Chiniforush, Mohadeseh Heidari
Summary: This study aimed to assess the effectiveness of adjunctive antimicrobial photodynamic therapy in treating peri-implant diseases in smokers. The results showed a significant difference in pocket depth and plaque index at the 3-month follow-up between the MD+a-PDT group and the MD alone group, but due to methodological heterogeneity and limited number of studies, conclusive evidence for the efficacy of a-PDT in improving clinical parameters in smokers is lacking.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ardavan Etemadi, Negar Imani, Ehsan Seyed Jafari, Nasim Chiniforush
Summary: This study found that multiple exposures to 660 nm PBMT laser, in conjunction with the passage of time, can increase the viability of human gingival fibroblasts following ICG-induced photodynamic therapy.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Sedighe Sadat Hashemikamangar, Ruqaya Jamal Falih Alsaedi, Nasim Chiniforush, Fariba Motevaselian
Summary: This study evaluated the influence of antimicrobial photodynamic therapy with phycocyanin and toluidine blue on the bond strength between resin composite and sound dentin. The results showed that aPDT had no significant effect on dentin bond strength, but the bond strength of total-etch groups was significantly reduced after aPDT. Phycocyanin self-etch group exhibited the highest bond strength compared to other aPDT groups.
CLINICAL ORAL INVESTIGATIONS
(2022)
Article
Biochemistry & Molecular Biology
Ardavan Etemadi, Aramdokht Faghih, Nasim Chiniforush
Summary: This study aimed to compare the efficacy of photobiomodulation therapy (PBMT) with different laser wavelengths and energy densities on the proliferation of human periodontal ligament mesenchymal stem cells (PDLMSCs). The results showed that PBMT with wavelengths of 635, 660, 808 and 980 nm can enhance the proliferation of PDLMSCs, and the maximum cell viability was observed after irradiation with 980 nm laser at an energy density of 4 J cm(-2).
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2022)
Article
Dentistry, Oral Surgery & Medicine
Farzaneh Afkhami, Hooman Ebrahimi, Arman Aghazadeh, Aidin Sooratgar, Nasim Chiniforush
Summary: The study found that photobiomodulation therapy prior to dental anesthetic injections does not have a clinical advantage for reducing injection pain.
DENTAL AND MEDICAL PROBLEMS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Nastaran Sharifi, Mohammad Sadegh Ahmad Akhoundi, Mahshid Hodjat, Nooshin Haghighipour, Setareh Kazemi Veysari
Summary: Periodontal ligament (PDL) cells are involved in mechanosensing and signaling molecule secretion during bone remodeling. This study investigated the expression pattern of periostin and sclerostin in response to orthodontic forces in PDL cells. The results showed that compression forces increased the expression of sclerostin, while tensile forces induced the expression of periostin. These findings suggest the important roles of periostin and sclerostin in orthodontic loads.
Article
Chemistry, Multidisciplinary
Shima Afrasiabi, Steven Parker, Nasim Chiniforush
Summary: This study compares the biofilm removal effects of methylene blue or hydrogen peroxide mediated photodynamic inactivation with a shock wave enhanced emission photoacoustic streaming (SWEEPS) method laser irradiation enhanced bactericidal activity. The results show that SWEEPS can enhance the distribution of photosensitizers in the root canal, leading to effective biofilm removal.
APPLIED SCIENCES-BASEL
(2023)
Article
Dentistry, Oral Surgery & Medicine
Siavash Abdollahpour, Tarane Estedlal, Nasim Chiniforush, Niyousha Rafeie, Nariman Nikparto, Mahdi Abbasi, Ladan Ranjbar Omrani
Summary: This study evaluated the effect of in-office, at-home, and laser-assisted bleaching on the monomer release from aged nanohybrid and microhybrid resin composites. The results showed that the bleaching method had no effect on the release of TEGDMA and BisGMA, but it increased the release of UDMA from the nanohybrid composite.
INTERNATIONAL JOURNAL OF DENTISTRY
(2023)
Article
Biochemistry & Molecular Biology
Golriz Rostami, Shima Afrasiabi, Stefano Benedicenti, Antonio Signore, Nasim Chiniforush
Summary: This study aimed to assess the efficacy of shockwave-enhanced emission photoacoustic streaming (SWEEPS) plus antimicrobial photodynamic therapy (aPDT) using indocyanine green (ICG) for the elimination of Enterococcus faecalis biofilm from infected root canals. The results showed that the ICG + 808 nm diode laser + SWEEPS group had significantly lower amounts of bacteria than either the ICG + 808 nm diode laser or SWEEPS group.
Article
Dentistry, Oral Surgery & Medicine
Shakiba Farahani, Taraneh Faghihi, Ladan Ranjbar Omrani, Nasim Chiniforush, Elham Ahmadi, Mandana Karimi, Mahdi Abbasi
Summary: This study examined the effects of laser and conventional in-office bleaching, and polishing on the color of stained composite resin. The results showed that both types of composite resin exhibited color changes after immersion in coffee solution, and the extent of color changes varied depending on the stain-removing methods used.
INTERNATIONAL JOURNAL OF DENTISTRY
(2023)
Article
Pharmacology & Pharmacy
Ali Shahi Ardakani, Shima Afrasiabi, Pegah Sarraf, Stefano Benedicenti, Luca Solimei, Nasim Chiniforush
Summary: The study showed that combining SWEEPS technique with riboflavin as a photosensitizer activated by BDL in aPDT effectively reduced the presence of Enterococcus faecalis in root canals.
Article
Oncology
Shima Afrasiabi, Sarvin Entezari, Ardavan Etemadi, Nasim Chiniforush
Summary: This study demonstrated that blue diode laser combined with curcumin has a strong bactericidal effect on Streptococcus mutans, and this effect is enhanced by increasing the power density. Additionally, chlorhexidine showed the highest reduction in colony numbers compared to the control group.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Oncology
Ardavan Etemadi, Seyed Shahabodin Hashemi, Nasim Chiniforush
Summary: The study evaluated the effect of Photodynamic therapy with Curcumin and Riboflavin on the decontamination of implant surfaces. The results showed that Photodynamic therapy with Curcumin significantly reduced the bacterial colonies on the implant surfaces, making it an effective method for reducing biofilm.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2023)
Article
Engineering, Biomedical
Mohammad Saeed Sheykhrezae, Khosrow Sohrabi, Farshad Khosraviani, Saba Mohammadi, Nasim Chiniforush, Pegah Sarraf
Summary: This study evaluated the effect of Nd:YAG laser on the bond strength of endodontic materials in the repair of artificial furcal perforations. The push-out bond strength was significantly higher in the MTA group compared to the CEM group, and increasing the laser power output from 1W to 1.5W did not have a significant influence on bond strength.
LASERS IN MEDICAL SCIENCE
(2022)
