Journal
LARYNGOSCOPE
Volume 118, Issue 1, Pages 24-31Publisher
JOHN WILEY & SONS INC
DOI: 10.1097/MLG.0b013e318155a276
Keywords
Radiation; taste; dysgeusia; videomicroscopy; taste pores
Funding
- Department of Veterans Affairs
- Philadelphia VA Medical Center
- Competitive Pilot Project Fund
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Objectives: To determine whether radiation alters taste function and structure. Research Design: Prospective, longitudinal study. Methodology: Testing prior to starting radiation, and 2 weeks, 2 months, and 6 months after completing radiation. Results: Relative to controls, patients had lower taste identification test scores for bitter, salty, and sour tastes. Sour taste also showed a significant group-by-time interaction (P = .03). Taste pores were decreased in the irradiated group, with a significant group-by-time interaction (P = .03). Conclusion: Head and neck cancer patients have decreased taste function, and radiation adversely affected sour taste and taste pores.
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