Article
Health Care Sciences & Services
Gabor Ruzsa, Fanni Rencz, Valentin Brodszky
Summary: This study developed an experimental value set for the Dermatology Life Quality Index (DLQI) by examining the relationship between time trade-off (TTO) utility valuations and DLQI severity levels characterizing dermatologically relevant health states. The study found that the social/interpersonal consequences of skin conditions had a larger impact on valuations compared to the physical/practical aspects, and there was significant heterogeneity across DLQI items.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Dermatology
Shinichi Imafuku, Yasumasa Kanai, Kenta Murotani, Takanobu Nomura, Kei Ito, Chika Ohata, Fumikazu Yamazaki, Takuya Miyagi, Hidetoshi Takahashi, Yukari Okubo, Hidehisa Saeki, Masaru Honma, Yayoi Tada, Tomotaka Mabuchi, Mari Higashiyama, Satomi Kobayashi, Yuki Hashimoto, Mariko Seishima, Tatsuyuki Kakuma
Summary: This study evaluated the importance of DLQI evaluation in Japanese patients with plaque psoriasis at the time of biologics introduction. The results showed that DLQI may be useful for assessing patient concerns during initiation or switching of biologics in clinical practice.
JOURNAL OF DERMATOLOGICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Yiran Chen, Lei Wei, Yu Song, Rui Zhang, Le Kuai, Bin Li, Ruiping Wang
Summary: This study aimed to explore the association between life quality based on the Dermatology Life Quality Index (DLQI) evaluation and disease severity among psoriasis patients in China. The study found that life quality based on DLQI evaluation was positively correlated with disease severity, especially among male patients and those with higher body mass index (BMI). Therefore, it is recommended that clinicians consider DLQI evaluation as an important indicator during patient treatment.
ANNALS OF MEDICINE
(2023)
Review
Dermatology
W. Y. Haw, A. Al-Janabi, B. W. M. Arents, L. Asfour, L. S. Exton, D. Grindlay, S. S. Khan, L. Manounah, H. Yen, C. -C. Chi, E. J. van Zuuren, C. Flohr, Z. Z. N. Yiu
Summary: The global production of dermatology clinical practice guidelines (CPGs) varies widely in geographical representation, article accessibility, and funding disclosure. The number of CPGs for skin diseases does not match their disease burden, with uneven distribution by geographical region. Skin cancers have a significant representation in CPGs, despite a lower burden ranking.
BRITISH JOURNAL OF DERMATOLOGY
(2021)
Article
Computer Science, Artificial Intelligence
Xiaojin Zhang, Yan Kang, Kai Chen, Lixin Fan, Qiang Yang
Summary: This article introduces the requirements for privacy protection and model utility improvement in federated learning and proposes a unified federated learning framework. The article also presents the No-Free-Lunch theorem for the federated learning system, indicating that it is unrealistic to expect excellent privacy, utility, and efficiency simultaneously in certain scenarios. Additionally, the article analyzes the lower bounds of several widely-adopted protection mechanisms, providing guidance for selecting appropriate protection parameters.
ACM TRANSACTIONS ON INTELLIGENT SYSTEMS AND TECHNOLOGY
(2023)
Article
Health Care Sciences & Services
John S. Barbieri, Zelma C. Chiesa Fuxench, Daniel B. Shin, Junko Takeshita
Summary: NRRs on the DLQI are common among adults with atopic dermatitis, but there is no clear association with other measures of disease severity.
QUALITY OF LIFE RESEARCH
(2021)
Article
Physics, Multidisciplinary
Xia Zeng, Chuanchuan Yang, Bin Dai
Summary: This paper investigates the trade-off between utility and privacy in distributed machine learning with the help of the differential privacy mechanism. It explores the relationship between utility and privacy in three cases, considering independent and dependent client local parameters with independent/dependent differential privacy noise. The optimal noise variance for achieving maximum utility under a certain level of privacy is also determined.
Article
Computer Science, Artificial Intelligence
Qihong Wu, Jinchuan Tang, Shuping Dang, Gaojie Chen
Summary: In this article, the authors propose a privacy funnel based on mutual information to optimize the trade-off between user privacy and data utility in the era of big data and IoT. The proposed approach uses a mutual information neural estimator (MINE) to estimate mutual information, and optimizes the privacy utility trade-off through an encoding and decoding process. Simulations show that the designed framework has better performance and faster convergence compared to traditional methods.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Health Care Sciences & Services
Jialin Liu, Changyu Wang, Siru Liu
Summary: ChatGPT has various applications in clinical practice, such as generating accurate differential diagnosis lists, supporting clinical decision-making, and providing reliable information about diseases. It is also effective in generating patient clinical letters and improving efficiency for healthcare providers.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Article
Medicine, Research & Experimental
Daniel O. Claassen, Rajeev Ayyagari, Debbie Goldschmidt, Mo Zhou, Sam Leo, Rinat Ribalov
Summary: This study estimated the impact of Huntington's disease chorea severity on quality of life using utility values from the general population. The results showed that as chorea severity increased, there was a significant decrease in utility values.
ADVANCES IN THERAPY
(2022)
Article
Dermatology
Ashley M. Snyder, Suephy C. Chen, Mary-Margaret Chren, Laura K. Ferris, LaVar D. Edwards, Robert A. Swerlick, Nicholas D. Flint, Amy M. Cizik, Rachel Hess, Jacob Kean, Aaron M. Secrest
Summary: With the increasing availability of disease- and symptom-specific measures and the proven usefulness of patient-reported outcome measures (PROMs), the routine use of PROMs in clinical care is now possible. PROMs can enhance healthcare efficiency, improve the clinician-patient relationship, and increase patient satisfaction. However, there are barriers to overcome, such as the cost of implementing the technology, selecting appropriate PROMs for different diseases, and helping patients and clinicians understand the value of PROMs. Recommendations are provided to assist dermatologists in incorporating PROMs into their practices.
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
(2023)
Review
Surgery
Agi M. McFarland, Sarkis Manoukian, Helen Mason, Jacqui S. Reilly
Summary: Surgical-site infections (SSIs) have a negative impact on patient quality of life. This study provides the first synthesized estimate of SSI burden over the short and long term, highlighting the importance of infection prevention planning and future economic modeling.
BRITISH JOURNAL OF SURGERY
(2023)
Article
Dermatology
Sarvin Sajedianfard, Farhad Handjani, Nasrin Saki, Alireza Heiran
Summary: Pemphigus vulgaris significantly affects the Family Dermatology Life Quality Index, with negative impact seen in male patients, older patients, those with shorter disease duration or fewer disease recurrences. Lower education level among family caregivers also results in poorer quality of life.
INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY
(2021)
Article
Dermatology
Yeon Chiat Teh, Chai Har Loo, Norazlima Mohd Ali, Ai Lee Lim, Wooi Chiang Tan
Summary: The study found that cutaneous lupus erythematosus (CLE) presents differently in different populations, with many patients showing systemic involvement and immunological abnormalities. This provides important insights for predicting disease severity and designing treatment strategies.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Health Care Sciences & Services
Rachel R. J. Kalf, Diana M. J. Delnoij, Bettina Ryll, Marcel L. Bouvy, Wim G. Goettsch
Summary: This study identified the important HRQoL topics for melanoma patients by analyzing web-based discussions on public social media forums. The most frequently discussed themes were mental health and (un)certainty, with fear, worry and anxiety, uncertainty, and unfavorable effects being the most commonly discussed codes. This research suggests that web-based forums can provide valuable insights for understanding patients' HRQoL and may enhance the content validity of patient-reported outcome measures.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2021)
Article
Economics
Kamilla Koszoru, Krisztina Hajdu, Valentin Brodszky, Alex Bato, L. Hunor Gergely, Aniko Kovacs, Zsuzsanna Beretzky, Miklos Sardy, Andrea Szegedi, Fanni Rencz
Summary: In adult patients with AD, EQ-5D-5L demonstrated superiority over EQ-5D-3L in terms of ceiling effects, informativity, and convergent validity. Therefore, we recommend the use of EQ-5D-5L to measure health outcomes in clinical settings and for QALY calculations in AD.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Public, Environmental & Occupational Health
Peter Gyorgy Balazs, Ariel Mitev, Valentin Brodszky
Summary: This study aims to validate and confirm the reliability of the Hungarian version of the Fear of COVID-19 Scale (FCV-19S), as well as evaluate its dimensional structure. The results showed significant differences in mean scores across different subgroups, and the items demonstrated good internal consistency. Both EFA and CFA analyses supported a two-dimensional structure, with factors identified as physiological fear and emotional fear.
Article
Public, Environmental & Occupational Health
Louisa-Kristin Muntendorf, Hans-Helmut Koenig, Luca Janssen, Irina Pokhilenko, Ruben Drost, Judit Simon, Lidia Garcia-Perez, Valentin Brodszky, Leona Hakkaart-van Roijen, A-La Park, Silvia Evers, Alexander Konnopka
Summary: This study aims to incorporate inter-sectoral unit costs of the German Criminal Justice Sector into health economic evaluations from a societal perspective. Through questionnaire surveys and direct correspondence, the unit costs for various sectors, such as police and fire brigade, were calculated. The lack of these costs highlights the importance of this research in health economic evaluations.
GESUNDHEITSOEKONOMIE UND QUALITAETSMANAGEMENT
(2023)
Review
Health Care Sciences & Services
Peter Gyorgy Balazs, Dalma Erdosi, Antal Zemplenyi, Valentin Brodszky
Summary: This study systematically reviews the literature on health utility in depression generated by the time trade-off (TTO) method and compares health state vignettes. The results show that patients perceive depression health states worse than healthy individuals.
QUALITY OF LIFE RESEARCH
(2023)
Article
Health Care Sciences & Services
Anna Nikl, Mathieu. F. F. Janssen, Valentin Brodszky, Fanni Rencz
Summary: This study aims to compare the measurement properties of the EQ-5D-5L and 15D in a general population sample. The results show that despite having 10 fewer dimensions, the EQ-5D-5L performs better than the 15D in many aspects. These findings help to understand the differences between generic preference-accompanied measures and support resource allocation decisions.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2023)
Article
Multidisciplinary Sciences
Aron Holgyesi, Barbara Toth, Miklos Kozlovszky, Jozsef Kuti, Miklos Weszl, Gyorgy Balazs, Petra Baji, Levente Kovacs, Laszlo Gulacsi, Zsombor Zrubka, Marta Pentek
Summary: This study aimed to investigate the epidemiology, characteristics, and current awareness levels of patients living with implantable medical devices (IMDs). The study found that nearly one third of respondents were living with IMDs, with tooth implants and intraocular lenses being the most common. Patients' knowledge levels varied by IMD types, and education and shared decision-making had a positive effect on patients' knowledge and impact on life.
Article
Health Care Sciences & Services
M. Mercedesz Angyal, Peter L. Lakatos, Balazs Jenei, Valentin Brodszky, Fanni Rencz
Summary: This study conducted a survey among 312 adult patients with celiac disease in Hungary to assess their health-related quality of life. The results showed that strict adherence to a gluten-free diet may lead to significant health improvements, and age, gender, symptom severity, and comorbidities can affect patients' assessments of their own health.
QUALITY OF LIFE RESEARCH
(2023)
Article
Health Care Sciences & Services
Balazs Jenei, Alex Bato, Ariel Z. Mitev, Valentin Brodszky, Fanni Rencz
Summary: The study aims to assess the psychometric properties of the Hungarian PROMIS-29+2 profile measure and establish general population reference values for Hungary. The results show satisfactory psychometric properties for PROMIS-29+2 overall, except for the sleep disturbance domain which requires further attention. Population reference values were generated to facilitate the interpretation of health outcomes in different patient populations.
QUALITY OF LIFE RESEARCH
(2023)
Article
Business, Finance
V. Meusel, E. Mentzakis, P. Baji, G. Fiorentini, F. Paolucci
Summary: Worldwide, social healthcare systems are facing the challenges of limited resources and their equitable distribution. In Germany, there is a need for more systematic priority setting procedures, and multi-criteria decision analysis (MCDA) has been identified as a promising approach. This study analyzed the preferences of German decision makers in setting priority interventions, showing a higher preference for efficiency criteria and highlighting mental disorders and cardiovascular diseases as high priority interventions.
INTERNATIONAL JOURNAL OF HEALTH ECONOMICS AND MANAGEMENT
(2023)
Article
Health Care Sciences & Services
Eszter Szlavicz, Akos Szabo, Agnes Kinyo, Anita Szeiffert, Tamas Bancsok, Valentin Brodszky, Rolland Gyulai, Fanni Rencz
Summary: The EQ-5D-5L with skin irritation and self-confidence bolt-ons demonstrated good content validity, comprehensiveness, and comprehensibility in patients with atopic dermatitis (AD). However, in terms of comprehensiveness, social relationships and judgement by others (stigma) may be missing from the questionnaire.
QUALITY OF LIFE RESEARCH
(2023)
Article
Medicine, General & Internal
Daniella Kuzmanovszki, Norbert Kiss, Bela Toth, Veronika Toth, Jozsef Szakonyi, Kende Lorincz, Judit Harsing, Eniko Kuroli, Eleonora Imredi, Tunde Kerner, Mihaly Patyanik, Norbert M. Wikonkal, Akos Szabo, Valentin Brodszky, Fanni Rencz, Peter Hollo
Summary: This retrospective real-world study revealed that locally advanced or metastatic cSCC could be effectively treated with cemiplimab even in elderly, polymorbid and immunocompromised patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Economics
Alex Bato, Valentin Brodszky, Ariel Zoltan Mitev, Balazs Jenei, Fanni Rencz
Summary: This study aimed to assess the psychometric properties of the Hungarian PROMIS-GH and develop general population reference values in Hungary. An online survey was conducted among the Hungarian general population, and age- and gender-weighted T-scores were computed. The results showed that PROMIS-GH has good validity and can be used in the general population in Hungary.
EUROPEAN JOURNAL OF HEALTH ECONOMICS
(2023)
Article
Geriatrics & Gerontology
Petra Baji, Rita Patel, Andrew Judge, Antony Johansen, Jill Griffin, Tim Chesser, Xavier L. Griffin, Muhammad K. Javaid, Estela C. Barbosa, Yoav Ben-Shlomo, Elsa M. R. Marques, C. L. Gregson
Summary: This study aimed to identify hospital-level organisational factors associated with long-term patient outcomes and costs after hip fracture. The study found that variations in hip fracture care delivery between hospitals can impact patient outcomes and health costs. The results can inform initiatives to improve the effectiveness and efficiency of hip fracture services.
LANCET HEALTHY LONGEVITY
(2023)
Meeting Abstract
Health Policy & Services
Irina Pokhilenko, Luca M. M. Janssen, Aggie T. G. Paulus, Ruben M. W. A. Drost, W. Hollingworth, Joanna C. Thorn, Sian Noble, Judit Simon, Claudia Fischer, Susanne Mayer, Luis Salvador-Carulla, Alexander Konnopka, Leona Hakkaart van Roijen, Valentin Brodszky, A-La Park, Silvia M. A. A. Evers
JOURNAL OF MENTAL HEALTH POLICY AND ECONOMICS
(2022)
Meeting Abstract
Economics
A. Holgyesi, G. Poor, L. Gulacsi, Z. Zrubka, M. Pentek