Article
Multidisciplinary Sciences
Isabelle Dore, Audrey Plante, Nathalie Bedrossian, Sarah Montminy, Kadia St-Onge, Jany St-Cyr, Marie-Pascale Pomey, Danielle Charpentier, Lise Pettigrew, Isabelle Brisson, Fred Saad, Francois Tournoux, Marie-France Raynault, Anne-Marie Mes-Masson, Lise Gauvin
Summary: This project aims to develop a practice guideline for physical activity promotion for cancer patients in clinical and community settings. By synthesizing knowledge, analyzing data, collecting and analyzing experiences from patients and healthcare providers, we hope to successfully integrate physical activity into cancer treatment and survivorship to improve the physical and mental health of patients.
Article
Obstetrics & Gynecology
M. Sousa-Leite, R. Costa, B. Figueiredo, S. Gameiro
Summary: This study examined patients' willingness to discuss the possibility of treatment being unsuccessful as part of routine care offered at clinics, and identified factors associated with this willingness. The results showed that 90% of patients were willing to discuss this possibility, and willingness was associated with higher perceived benefits, lower barriers, and stronger positive attitudes towards it.
HUMAN REPRODUCTION
(2023)
Editorial Material
Oncology
William E. Rosa, Kristin Levoy, Katherine Doyon, Meghan Mcdarby, Betty R. Ferrell, Patricia A. Parker, Justin J. Sanders, Andrew S. Epstein, Donald R. Sullivan, Abby R. Rosenberg
Summary: The global incidence of cancer and available cancer-directed therapy options is increasing rapidly, presenting patients and clinicians with more complex treatment decisions than ever before. Despite the dissemination of evidence-based communication training tools and programs, clinicians cite barriers to employing effective communication in cancer care. This article presents two composite cases with communication challenges and provides evidence-based approaches to achieve quality communication.
SUPPORTIVE CARE IN CANCER
(2023)
Review
Oncology
Cecile Torregrosa, Frederic Chorin, Eva Ester Molina Beltran, Cindy Neuzillet, Victoire Cardot-Ruffino
Summary: This literature review focuses on adapted physical exercise in the management of cancer patients, aiming to raise awareness among medical staff about its importance. The benefits of exercise are summarized from physiological, pathophysiological, and cellular perspectives, as well as the interactions between individuals and their environment. Integration of exercise dimensions with oncological treatments in multidisciplinary supportive care is considered a new paradigm to improve patient survival and quality of life. This emerging field of exercise oncology aims to understand the biological mechanisms by which aerobic exercise affects cancer incidence, progression, and metastases. The article provides an overview of current physical exercise interventions in cancer patient management, as well as discussing potential clinical applications and the importance of personalized, integrated, patient-centered, and multidisciplinary approaches.
Article
Medicine, General & Internal
Kilian Rapp, Sarah E. Lamb, Patrick Roigk, Clemens Becker, Claudia Konnopka, Hans-Helmut Konig, Raphael S. Peter, Dietrich Rothenbacher, Gisela Buchele
Summary: This study evaluated a comprehensive preventive intervention for fracture prevention among older people living in rural areas in Germany. Although the program did not impact the overall incidence of fragility fractures, it did show a reduction in femoral fractures, the most common fracture type. Overall, the program has positive implications for preventing fractures in older adults.
Review
Medicine, General & Internal
Mahnaz Bahri Khomami, Helena J. Teede, Joanne Enticott, Sharleen O'Reilly, Cate Bailey, Cheryce L. Harrison
Summary: Despite the substantial evidence on the efficacy of lifestyle interventions during pregnancy in optimizing gestational weight gain, there is a lack of guidance on how to implement this evidence into practice. More implementation research is needed to improve the health of pregnant women and the next generation.
Article
Genetics & Heredity
Kimberly A. Kaphingst, Jemar R. Bather, Brianne M. Daly, Daniel Chavez-Yenter, Alexis Vega, Wendy K. Kohlmann
Summary: This study examined the interest and predictors of cancer predisposition testing and carrier screening among an ethnically diverse sample of young women. The findings showed that there is substantial interest in these tests as part of routine healthcare, with similar levels of interest between Latina and non-Latina women. Factors such as higher worry about genetic risks, higher genetic knowledge, and higher perceived importance of genetic information were associated with higher interest in these tests.
FRONTIERS IN GENETICS
(2022)
Article
Obstetrics & Gynecology
Shivani Nazareth, Laura Hayward, Emilie Simmons, Moran Snir, Kathryn E. Hatchell, Susan Rojahn, Robert Nathan Slotnick, Robert L. Nussbaum
Summary: The study showed high user acceptance and engagement with a clinical chathot that automates hereditary cancer risk triage in women's health care settings. Most participants completed the cancer risk assessment and educational section, indicating high acceptability among those who opted to engage. The chathot tool effectively identified high-risk patients for hereditary cancer syndromes before routine care appointments and facilitated a path towards preventive genetic testing.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Health Care Sciences & Services
Neil S. Wenger, Annette L. Stanton, Ryan Baxter-King, Karen Sepucha, Lynn Vavreck, Arash Naeim
Summary: COVID-19 restrictions and fear have significantly affected the use of medical care. This study examines the proportion of cancelled or postponed medical visits and cancer screenings and identifies the factors associated with these cancellations. The results show that individuals with medical conditions, anxiety, and depression were more likely to cancel or postpone medical appointments and screenings. Outreach and support are important to ensure that patients with these conditions receive the necessary care without avoiding it due to anxiety and inaccurate risk perceptions.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2022)
Article
Oncology
Louise Czosnek, Nicole M. Rankin, Prue Cormie, Andrew Murnane, Jane Turner, Justin Richards, Simon Rosenbaum, Eva M. Zopf
Summary: This study developed causal pathways to explain the how and why of successful implementation of exercise EBIs in cancer care. The study identified 11 common pathways that help understand and plan future exercise interventions, allowing cancer survivors to benefit from exercise.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Public, Environmental & Occupational Health
Alessandra Da Ros, Matteo Paci, Elisa Buonandi, Laura Rosiello, Sandra Moretti, Chiara Barchielli
Summary: This study describes the Family and Community Physiotherapist model in Tuscany, Italy, which aims to incorporate rehabilitation services into primary health care. Through the implementation of an organizational case study, the model successfully provides rehabilitative care in the community, preventing exacerbation of chronic conditions.
BULLETIN OF THE WORLD HEALTH ORGANIZATION
(2022)
Article
Oncology
Hugh Elbourne, Wee Kheng Soo, Victoria O'Reilly, Anna Moran, Christopher B. Steer
Summary: Despite a third of patient respondents indicating an interest in a supervised exercise program, only 16% of patients with prostate cancer undergoing ADT at a regional cancer centre engaged in a discussion about exercise with their treating clinicians. Physical limitations and fatigue were the greatest barriers for patients. Clinicians indicated a need for more clinician education and better integration of exercise specialists into clinical care.
SUPPORTIVE CARE IN CANCER
(2022)
Review
Medicine, General & Internal
Lara Edbrooke, Amy Bowman, Catherine L. Granger, Nicola Burgess, Shaza Abo, Bronwen Connolly, Linda Denehy
Summary: This overview summarizes the efficacy and safety of exercise interventions in lung cancer patients. The results show that exercise can reduce post-operative complications and improve exercise capacity, but has no significant impact on health-related quality of life. Most studies included surgical patients, with limited research on non-surgical populations.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Oncology
Kyra Bokkers, Michiel Vlaming, Ellen G. Engelhardt, Ronald P. Zweemer, Inge M. van Oort, Lambertus A. L. M. Kiemeney, Eveline M. A. Bleiker, Margreet G. E. M. Ausems
Summary: This systematic review found that mainstream genetic testing appears to be feasible in daily practice without insurmountable barriers. A structured pathway with a training procedure is desirable, as well as a close collaboration between genetics and other clinical departments.
Review
Oncology
Aylin Tanriverdi, Buse Ozcan Kahraman, Gulbin Ergin, Didem Karadibak, Sema Savci
Summary: The purpose of this study is to examine the effects of exercise intervention on exercise capacity, physical function, and patient-reported outcome measures in adults with cancer receiving palliative care. A systematic review and meta-analysis of 14 studies and 1034 adults with cancer receiving palliative care showed that exercise interventions significantly improved exercise capacity, pain, fatigue, and quality of life.
SUPPORTIVE CARE IN CANCER
(2023)
Article
Rehabilitation
Encarna Camacho Perez, Samantha Mayo, Jeffrey H. Lipton, Eugene Chang, Lyndsey De Souza, Daniel Santa Mina
Summary: This study aimed to evaluate a group-based rehabilitation program consisting of exercise and relaxation classes for inpatients undergoing allogeneic hematopoietic stem cell transplant (allo-HSCT). The results showed that group-based exercise and relaxation classes were feasible and safe during hospitalization, but there were pragmatic barriers to optimal program implementation. Further research is needed to examine program effectiveness and adoption.
Review
Rehabilitation
Leah J. Mercier, Chris Grant, David M. Langelier, Stephanie Plamondon
Summary: This review discusses the use of music therapy and music-based interventions in the rehabilitation and health of individuals with spinal cord injury. The findings suggest that these interventions have the potential to improve various outcomes, but more randomized controlled trials are needed to validate their effectiveness.
DISABILITY AND REHABILITATION
(2023)
Article
Nutrition & Dietetics
Chelsia Gillis, Miquel Coca-Martinez, Daniel Santa Mina
Summary: Mounting evidence suggests that recovery begins before the surgical incision, and the presurgery phase of recovery plays a crucial role in achieving optimal surgical outcomes. Prehabilitation, which focuses on enhancing individual functional capacity, can significantly improve patient outcomes when combined with individualized and coordinated care from medical, nutritional, psychosocial, and exercise services.
JOURNAL OF HUMAN NUTRITION AND DIETETICS
(2023)
Article
Rehabilitation
Leah J. Mercier, David M. Langelier, Chel Hee Lee, Brenda Brown-Hall, Christopher Grant, Stephanie Plamondon
Summary: This study aimed to evaluate the impact of music therapy (MT) on mood and pain, as well as explore its effects on satisfaction from the perspective of patients, families, and staff. The results showed significant improvements in mood and pain after the MT session, with 74% of participants reporting high satisfaction. The benefits of MT included emotional regulation, pain management, effects on self-concept, enjoyment, and social connectedness. Further evaluation is needed to assess the effectiveness of MT compared to standard rehabilitation care and its cost implications.
DISABILITY AND REHABILITATION
(2023)
Article
Oncology
Milothy Parthipan, Gregory Feng, Nelly Toledano, Valentina Donison, Henriette Breunis, Abirami Sudharshan, Urban Emmenegger, Antonio Finelli, Padraig Warde, Enrique Soto-Perez-de-Celis, Monika Krzyzanowska, Andrew Matthew, Hance Clarke, Daniel Santa Mina, Shabbir M. H. Alibhai, Martine Puts
Summary: Studying the symptom experiences of older men with metastatic prostate cancer during treatment can help identify unmet supportive care needs and improve patient wellbeing. Previous research has focused on the psychological experience rather than the overall symptom experience. The objective of this study was to understand the lived experience of symptoms and supportive care needs in older men undergoing treatment for metastatic prostate cancer.
JOURNAL OF GERIATRIC ONCOLOGY
(2023)
Article
Immunology
Hai Chuan Yu, Valery Kleiman, Katarina Kojic, P. Maxwell Slepian, Henry Cortes, Karen McRae, Rita Katznelson, Alex Huang, Diana Tamir, Joseph Fiorellino, Praveen Ganty, Nathalie Cote, Michael Kahn, Istvan Mucsi, Nazia Selzner, Dmitry Rozenberg, Cecilia Chaparro, Vivek Rao, Marcelo Cypel, Anand Ghanekar, Sharath Kona, Stuart McCluskey, Salima Ladak, Daniel Santa Mina, Keyvan Karkouti, Joel Katz, Hance Clarke
Summary: In this retrospective cohort study of 140 solid organ transplant patients, treatment by the TGH Transitional Pain Service team resulted in reduced opioid consumption and significant improvement in pain severity. Therefore, robust follow-up and management by a multidisciplinary team should be considered after solid organ transplantation to prevent chronic postsurgical pain, guide opioid weaning, and provide psychological support to improve patient recovery and quality of life.
Article
Health Care Sciences & Services
Dmitry Rozenberg, Noor Al Kaabi, Encarna Camacho Perez, Sahar Nourouzpour, Laura Lopez-Hernandez, Laura McGillis, Ewan Goligher, W. Darlene Reid, Chung-Wai Chow, Clodagh M. Ryan, Dinesh Kumbhare, Ella Huszti, Kateri Champagne, Satish Raj, Susanna Mak, Daniel Santa Mina, Hance Clarke, Nimish Mittal
Summary: This study aims to evaluate the factors associated with dyspnea and assess the feasibility and effectiveness of inspiratory muscle training (IMT) combined with standard-of-care rehabilitation. The study will include patients with hypermobile Ehlers-Danlos Syndrome (hEDS) or generalized hypermobility spectrum disorder (G-HSD) and healthy controls. The results are expected to be completed by the end of 2023.
JMIR RESEARCH PROTOCOLS
(2023)
Review
Nutrition & Dietetics
Daniel Sibley, Maggie Chen, Malcolm A. West, Andrew G. Matthew, Daniel Santa Mina, Ian Randall
Summary: Continuous advances in prehabilitation research have improved preoperative risk factors but the evidence for reducing surgical complications remains uncertain. This narrative review discusses the current evidence for the biological plausibility of multimodal prehabilitation to reduce surgical complications and highlights the need for more research in this area. The review outlines potential mechanisms, such as anti-inflammation and enhanced immune response, and suggests future investigations include these mechanisms.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2023)
Review
Health Care Sciences & Services
Christian J. Lopez, Kylie Teggart, Mohammed Ahmed, Anita Borhani, Jeffrey Kong, Rouhi Fazelzad, David M. Langelier, Kristin L. Campbell, Tony Reiman, Jonathan Greenland, Jennifer M. Jones, Sarah E. Neil-Sztramko
Summary: Electronic prospective surveillance models (ePSMs) are implemented in cancer care to monitor the development of treatment toxicities and impairments using electronic patient-reported outcomes. They aim to bridge the knowledge-to-practice gap between the high incidence of impairments and low uptake of rehabilitation services.
IMPLEMENTATION SCIENCE
(2023)
Article
Multidisciplinary Sciences
Samantha Tam, Rajat Kumar, Paty Lopez, Jonas Mattsson, Shabbir Alibhai, Eshetu G. Atenafu, Lori J. Bernstein, Eugene Chang, Susan Clarke, David Langelier, Jeffrey Lipton, Samantha Mayo, Tina Papadakos, Jennifer Michelle Jones
Summary: This study aims to develop a 6-month rehabilitation program for patients undergoing alloBMT and test the feasibility and acceptability of the program through a randomized controlled trial. It will also collect secondary clinical outcomes to inform future research.
Article
Health Care Sciences & Services
Dmitry Rozenberg, Josh Shore, Encarna Camacho Perez, Sahar Nourouzpour, Megha Ibrahim Masthan, Daniel Santa Mina, Jennifer L. Campos, Ella Huszti, Robin Green, Mohammad Hashim Khan, Ambrose Lau, David Gold, Matthew B. Stanbrook, W. Darlene Reid
Summary: Chronic obstructive pulmonary disease (COPD) is a progressive condition that affects physical and cognitive function, making it difficult for patients to perform dual tasks. Pulmonary rehabilitation mainly focuses on physical training, but evidence suggests that cognitive decline is also a significant factor contributing to functional limitations and decreased quality of life. This study aims to evaluate the feasibility and efficacy of a cognitive-physical training program compared to physical training alone for patients with COPD.
JMIR RESEARCH PROTOCOLS
(2023)
Review
Oncology
S. Sattar, E. Papadopoulos, G. V. H. Smith, K. R. Haase, F. Kobekyaa, I. Tejero, C. Bradley, M. B. Nadler, K. L. Campbell, D. Santa Mina, S. M. H. Alibhai
Summary: Technology-based remotely delivered exercise interventions appear to be feasible and acceptable in older adults with cancer.
JOURNAL OF CANCER SURVIVORSHIP
(2023)
Article
Oncology
Alexia Piche, Daniel Santa Mina, Sylvie Lambert, Isabelle Dore
Summary: This study developed a group-based, multimodal, tele-prehabilitation intervention for individuals diagnosed with cancer (iACTIF) and evaluated its feasibility, acceptability, fidelity, and preliminary effects in a real-world clinical setting. The results suggest that iACTIF is promising for implementation in clinical settings, with moderate benefits on physical health and a small increase in mental health indicators.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
Lauren C. Capozzi, Julia T. Daun, George J. Francis, Marie de Guzman Wilding, Gloria Roldan Urgoiti, David Langelier, Nicole Culos-Reed
Summary: Individuals living with and beyond cancer often experience physical impairments and inactivity. Specifically, neuro-oncology patients have higher rates of sedentary behavior and functional deficits. This study examined the feasibility of a triage clinic to assess rehabilitation and exercise needs for brain tumor patients. It was found that the clinic was safe and effective in facilitating referrals to appropriate resources, but barriers such as forgetting to refer patients and uncertainty of eligibility were identified. To improve identification and referral, a screening tool called the Cancer Rehabilitation and Exercise Screening Tool (CREST) is proposed.
