Review
Nutrition & Dietetics
Li Cai, Gaoming Wang, Peijun Zhang, Xinyi Hu, Hao Zhang, Fan Wang, Yeqing Tong
Summary: Inflammatory responses are highly associated with the progression of various lung diseases, and vitamin D has the potential to modulate immune functions and induce inflammatory responses, making it a potential adjunctive therapy for the prevention and treatment of lung diseases. This paper reviews the role of vitamin D in tuberculosis and suggests its potential as a safe adjunctive therapy, providing motivation for further research and clinical applications.
FRONTIERS IN NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
Tobias Niedermaier, Thomas Gredner, Sabine Kuznia, Ben Schoettker, Ute Mons, Jeroen Lakerveld, Wolfgang Ahrens, Hermann Brenner
Summary: This study estimates the potential impact of current and potential vitamin D fortification policies on reducing cancer mortality in European countries. Current fortification is estimated to prevent approximately 11,000 cancer deaths in the EU and 27,000 in all European countries considered per year. If all countries implement adequate fortification, an estimated additional 129,000 cancer deaths could be prevented, contributing to a significant reduction in cancer mortality burden in Europe.
EUROPEAN JOURNAL OF EPIDEMIOLOGY
(2022)
Review
Infectious Diseases
Giulia Patti, Carmen Pellegrino, Aurelia Ricciardi, Roberta Novara, Sergio Cotugno, Roberta Papagni, Giacomo Guido, Valentina Totaro, Giuseppina De Iaco, Federica Romanelli, Stefania Stolfa, Maria Letizia Minardi, Luigi Ronga, Ilenia Fato, Rossana Lattanzio, Davide Fiore Bavaro, Gina Gualano, Loredana Sarmati, Annalisa Saracino, Fabrizio Palmieri, Francesco Di Gennaro
Summary: Supplementation with multiple micronutrients, including zinc, may be more beneficial in TB compared to vitamin A alone. Vitamin C at high concentrations sterilizes drug-resistant TB cultures and prevents the emergence of drug persisters; Vitamin D suppresses mycobacterium replication in vitro, while VE shows a promising role in TB management due to its connection with oxidative balance.
Article
Pharmacology & Pharmacy
Laszlo Horvath, Sara Mirani, Michael Magdy Fahmy Girgis, Szilvia Racz, Ildiko Bacskay, Harjit Pal Bhattoa, Bela E. Toth
Summary: This study aimed to examine the vitD status of patients, explore the relationship between vitD deficiency and certain diseases, assess seasonality and trends, and reveal the indirect impact of the COVID-19 pandemic on vitD(3) supplementation at the population level. The results showed that 20% of all patients had hypovitaminosis D and males had higher odds for hypovitaminosis or vitD deficiency. VitD consumption exhibited seasonality, with higher consumption in autumn and winter. The findings highlight the importance of vitD(3) supplementation for at-risk groups and health education promoting vitamin D-3 supplementation.
FRONTIERS IN PHARMACOLOGY
(2023)
Review
Nutrition & Dietetics
Ana Palanca, Francisco Javier Ampudia-Blasco, Jose T. Real
Summary: Thyroid cancer is increasing in incidence and vitamin D may have a role in its prevention. However, the exact role of vitamin D in thyroid cancer development is controversial. Some studies suggest elevated serum vitamin D levels have a protective role, while others show no inverse relationship with the occurrence of thyroid cancer. Circulating vitamin D concentration is inversely correlated with disease aggressiveness and poor prognosis.
Article
Endocrinology & Metabolism
Fei-Long Wei, Tian Li, Quan-You Gao, Yuli Huang, Cheng-Pei Zhou, Wen Wang, Ji-Xian Qian
Summary: This study concluded that daily doses of 700 IU to 2000 IU of supplemental vitamin D were associated with a lower risk of falls among ambulatory and institutionalized older adults. High-dose vitamin D was effective in preventing falls, while low-dose vitamin D showed no significant effect. The preventive effect of vitamin D on falls was influenced by supplemental calcium, concentration, and frequency.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Davaasambuu Ganmaa, Tserendorj Chinbayar, Polyna Khudaykov, Erdenebileg Nasantogtoh, Sukhbaatar Ariunbuyan, Tserenkhuu Enkhtsetseg, Ganbold Sarangua, Andrew Chan, Dalkh Tserendagva
Summary: In Mongolian inpatients with COVID-19, active TB infection, older age, male gender, and COPD were associated with greater disease severity, while a history of COVID-19 vaccination and the presence of a BCG vaccination scar were protective.
Review
Nutrition & Dietetics
Stephanie Marie Cruz-Pierard, Teresa Nestares, Francisco J. Amaro-Gahete
Summary: Vitamin D supplementation has a protective effect in the prevention and treatment of CRC, while calcium intake shows contradictory effects and further studies are needed to understand its relevance in patients with CRC.
Review
Endocrinology & Metabolism
Salvatore Sciacchitano, Carlo Capalbo, Christian Napoli, Paolo Anibaldi, Valentina Salvati, Claudia De Vitis, Rita Mancini, Flaminia Coluzzi, Monica Rocco
Summary: Nonthyroidal illness syndrome (NTIS) is common in patients admitted to intensive care units. Whether NTIS should be treated or not is still debated. There is significant heterogeneity in the type of thyroid hormone supplementation, route of administration, dosages and duration of treatment in the current research, as well as variability in the chosen outcomes to evaluate the results.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Review
Pharmacology & Pharmacy
Carsten Carlberg, Eunike Velleuer
Summary: Low vitamin D status is a risk factor for colon, prostate, breast, and leukocyte cancers. Lifestyle adjustments can help control cancer risk. Vitamin D has anti-cancer effects on neoplastic cells and immune cells.
BIOCHEMICAL PHARMACOLOGY
(2022)
Article
Pediatrics
Lisa Stockdale, Basil Sambou, Muhamed Sissoko, Uzochukwu Egere, Abdou K. Sillah, Beate Kampmann, Robin Basu Roy
Summary: This study found that children with equal exposure to a TB case had higher levels of vitamin D if they were not infected, despite there being no significant difference in vitamin D levels between infected and uninfected children. The relationship between vitamin D levels and TB infection risk requires further investigation in larger studies to fully understand the implications and significance.
EUROPEAN JOURNAL OF PEDIATRICS
(2022)
Editorial Material
Nutrition & Dietetics
Hermann Brenner
Summary: The COVID-19 pandemic has posed an unprecedented threat to global public health and economies, with vitamin D supplementation suggested as a potential option to prevent infections and severe cases, especially among high-risk populations. Despite remaining uncertainties, accumulating evidence strongly supports widespread vitamin D supplementation, particularly for high-risk groups and infected individuals.
Article
Multidisciplinary Sciences
Ester Lilian Acen, Irene Andia Biraro, Mudarshiru Bbuye, David Patrick Kateete, Moses L. Joloba, William Worodria
Summary: The aim of this study was to determine the association between vitamin D deficiency and TB status among patients with active TB, latent TB infection (LTBI) and those without TB infection. The study found that the vitamin D levels of active TB patients were significantly lower compared to individuals with LTBI and those without TB infection.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Tobias Niedermaier, Thomas Gredner, Sabine Kuznia, Ben Schoettker, Ute Mons, Hermann Brenner
Summary: Recent meta-analyses have shown that vitamin D supplementation can significantly reduce cancer mortality. In Germany, the estimated cost and savings for preventing cancer deaths through vitamin D supplementation for the population aged 50+ is approximately 254 million euros. Vitamin D supplementation is estimated to prevent almost 30,000 cancer deaths per year.
MOLECULAR ONCOLOGY
(2021)
Article
Multidisciplinary Sciences
Ganesh Jevalikar, Ambrish Mithal, Anshu Singh, Rutuja Sharma, Khalid J. Farooqui, Shama Mahendru, Arun Dewan, Sandeep Budhiraja
Summary: The study found that there was no significant difference in clinical outcomes or mortality between COVID-19 hospitalized patients with Vitamin D deficiency (VDD) and those without VDD, and serum 25-OHD levels did not correlate with inflammatory markers. Treatment with cholecalciferol for VDD did not impact outcomes.
SCIENTIFIC REPORTS
(2021)
