Article
Multidisciplinary Sciences
Roman Cuberek, Marcela Janikova, Jan Dygryn
Summary: The study successfully translated the PAQ-C questionnaire into Czech and assessed its psychometric properties in older children. The PAQ-C/CZ can be recommended as a tool for assessing moderate-to-vigorous physical activity in large-sample research studies, with an emphasis on the interpretation of results.
Article
Psychology, Multidisciplinary
Ana Fonseca, Maria Cristina Canavarro, Helena Moreira
Summary: This study used a bifactor model to examine the dimensionality of the Parental Acceptance Questionnaire (6-PAQ) in Portuguese parents, and found support for its unidimensionality and the ability to compute a total score.
CURRENT PSYCHOLOGY
(2022)
Article
Biotechnology & Applied Microbiology
Eshetu Andarge, Robert Trevethan, Teshale Fikadu
Summary: The study examined the applicability and effectiveness of the Physical Activity Questionnaire for Adolescents (PAQ-A) in an Ethiopian setting. It found that while most items on the scale were satisfactorily interrelated and loaded on a single factor in factor analyses, there were some deficiencies in the scale's properties according to stringent or conventionally accepted psychometric criteria. Recommendations for presentation and scoring of the PAQ-A were made to enhance its validity beyond Ethiopia.
BIOMED RESEARCH INTERNATIONAL
(2021)
Article
Pediatrics
Laura Bechtiger, Annekatrin Steinhoff, Jessica M. Dollar, Susan D. Calkins, Susan P. Keane, Lenka Shriver, Laurie Wideman, Lilly Shanahan
Summary: The study found that maternal depressive symptoms in early, middle, and adolescence stages are directly and indirectly associated with adolescents' unhealthy behaviors. Promoting mothers' mental health is crucial for promoting children's health behaviors and overall health.
Article
Multidisciplinary Sciences
Dongfeng Liang, Xiangli Yu, Xiaojie Guo, Jie Zhang, Ronghuan Jiang
Summary: The aim of the study was to adapt and validate a Chinese version of the CSI-9, a patient-reported instrument used to screen people at risk of central sensitization. The Chinese CSI-9 was administered to patients with chronic pain and healthy controls, and its structural validity, construct validity, test-retest reliability, and internal consistency were evaluated. The results showed that the Chinese CSI-9 had good structural validity and construct validity, as well as reliable test-retest reliability and internal consistency.
Article
Psychology, Multidisciplinary
Qingsong Tan, Linting Zhang, Wenjie Li, Feng Kong
Summary: The study demonstrates that the Flourishing Scale maintains strong longitudinal invariance over a period of time and across different genders, with high stability coefficients observed. This suggests that the scale is a reliable measure for assessing well-being in adolescents.
CURRENT PSYCHOLOGY
(2021)
Article
Psychology, Multidisciplinary
Zhiqiang Yang, Yongqiang Zeng, Zhifang Li, Zhiqing Lin
Summary: Many factors may affect the speaking performance of test-takers in speaking assessment, such as characteristics of test-takers, test tasks, rating bias, etc. This study explores the construct validity of the PRETCO-Oral assessment through analysis of data from various sources. The results indicate that raters' ratings are stable and the assessment shows longitudinal reliability. Tasks of Interpretation and Presentation have a significant impact on the construct, while those of Reading Aloud and Question and Answer seem to be underrepresented.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Yuwei Pan, Jitka Pikhartova, Martin Bobak, Hynek Pikhart
Summary: In the Chinese middle-aged and older population, the reliability of SRH is generally good, although the two commonly used versions of SRH scales could not be compared directly. Both indices predict mortality, with similar predictive validity.
Article
Pharmacology & Pharmacy
Zhigang Guo, Liguang Zheng, Mengyuan Fu, Huangqianyu Li, Lin Bai, Xiaodong Guan, Luwen Shi
Summary: This study examined the effects of the full coverage policy for essential medicines (FCPEMs) on income-related inequality in medication adherence among patients with hypertension or diabetes in Taizhou, China. The results showed that FCPEMs improved medication adherence, although inequality did not consistently improve.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Nutrition & Dietetics
Franziska Jannasch, Daniela Nickel, Matthias B. Schulze
Summary: The study aimed to evaluate the ability of FFQ to describe dietary pattern scores, finding that predefined indices had higher correlations, but exploratory DP had only moderate accuracy with differences in validity.
BRITISH JOURNAL OF NUTRITION
(2021)
Article
Nutrition & Dietetics
Chenxi Qin, Yu Guo, Pei Pei, Huaidong Du, Ling Yang, Yiping Chen, Xi Shen, Zumin Shi, Lu Qi, Junshi Chen, Zhengming Chen, Canqing Yu, Jun Lv, Liming Li
Summary: This study evaluated the validity and reproducibility of qualitative and quantitative food frequency questionnaires (FFQs) in the Chinese population. The results showed that most food items in both the qualitative and quantitative FFQs had acceptable or good validity and reproducibility in the CKB study. However, dried vegetables and carbonated soft drinks performed poorly, indicating the need for modification and validation in future research.
Article
Psychology, Multidisciplinary
Pei-Yun Chen, Wen-Chao Ho, Chyi Lo, Tzu-Pei Yeh
Summary: The present study aimed to construct a short form Chinese Inventory of Psychosocial Balance (CIPB-SF) and validate its reliability and validity. The results showed that the 40-item CIPB-SF had good internal consistency and acceptable validity, making it suitable for application among the Chinese elderly population.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Multidisciplinary Sciences
Agnete Skovlund Dissing, Thea Otte Andersen, Andreas Kryger Jensen, Rikke Lund, Naja Hulvej Rod
Summary: Frequent nighttime smartphone use may disturb sleep patterns but does not strongly increase the risk of poor mental health. The study found a slight association between nighttime smartphone use and perceived stress and depressive symptoms at baseline, but this association was not replicated at follow-up.
SCIENTIFIC REPORTS
(2022)
Article
Dermatology
G. Schwartzman, D. Lei, A. Ahmed, R. Chavda, S. Gabriel, J. Silverberg
Summary: The study showed that patients with AD have a heterogeneous longitudinal course and distinct patterns of HRQoL. Many patients experienced fluctuating HRQoL over time. Most patients with moderate to severe disease at baseline had persistent HRQoL impairment over time.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2022)
Article
Psychiatry
Kamelia Harris, Gillian Haddock, Sarah Peters, Patricia Gooding
Summary: This study assessed the validity, reliability, and factor structure of the Suicidal Ideation Attributes Scale (SIDAS) in individuals with schizophrenia or non-affective psychosis. The SIDAS showed good construct validity, internal consistency, and test-retest reliability, and was highly correlated with other self-report measures. Further research is needed to test the scale's psychometric properties in individuals experiencing different mental health problems in cross-cultural settings.
Article
Genetics & Heredity
Chunyu Liu, Ying Shen, Shuyan Tang, Jiaxiong Wang, Yiling Zhou, Shixiong Tian, Huan Wu, Jiangshan Cong, Xiaojin He, Li Jin, Yunxia Cao, Yihong Yang, Feng Zhang
Summary: In this study, we investigated a group of Han Chinese men with asthenoteratozoospermia, a common type of male infertility. Through whole-exome sequencing, we identified AKAP3 as a novel gene associated with multiple morphological abnormalities of the sperm flagella (MMAF). Two different deleterious variants of AKAP3 were found in unrelated MMAF-affected men, and subsequent experiments confirmed the impact of these variants on AKAP3 expression in spermatozoa. Interestingly, the clinical outcomes after intracytoplasmic sperm injection (ICSI) were different between these two cases, suggesting that AKAP3 dosage may influence the prognosis of ICSI treatment.
JOURNAL OF MEDICAL GENETICS
(2023)
Article
Clinical Neurology
Yingzhe Wang, Yanfeng Jiang, Wanqing Wu, Kelin Xu, Qianhua Zhao, Ziyi Tan, Xiaoniu Liang, Min Fan, Zhenxu Xiao, Li Zheng, Saineng Ding, Qiang Dong, Zhen Hong, Li Jin, Xingdong Chen, Ding Ding, Mei Cui
Summary: The study found that older adults with higher educational attainment showed slower cognitive decline. Education is especially important for maintaining cognitive health in disadvantaged living environments.
ALZHEIMERS & DEMENTIA
(2023)
Article
Biochemistry & Molecular Biology
Yimin Wang, Yunchao Ling, Jiao Gong, Xiaohan Zhao, Hanwen Zhou, Bo Xie, Haiyi Lou, Xinhao Zhuang, Li Jin, Shaohua Fan, Guoqing Zhang, Shuhua Xu
Summary: PGG.SV is a practical platform that provides large-scale structural variation data, including 1030 long-read sequencing genomes representing 177 global populations. The database offers high-quality SVs with precise genomic locations, estimates of SV prevalence in different geographical populations, informative annotations of related genes, and an analysis platform and visualization tools for association studies.
NUCLEIC ACIDS RESEARCH
(2023)
Letter
Biochemistry & Molecular Biology
Shixiong Tian, Ziqi Wang, Liting Liu, Yiling Zhou, Yue Lv, Dongdong Tang, Jiaxiong Wang, Jing Jiang, Huan Wu, Shuyan Tang, Guanxiong Wang, Hao Geng, Fangbiao Tao, Hongbin Liu, Xiaojin He, Feng Zhang, Jinsong Li, Li Jin, Tao Huang, Chunyu Liu, Yunxia Cao
JOURNAL OF GENETICS AND GENOMICS
(2023)
Article
Dermatology
Qianqian Peng, Yu Liu, Anke Huels, Canfeng Zhang, Yao Yu, Wenqing Qiu, Xiyang Cai, Yuepu Zhao, Tamara Schikowski, Katja Merches, Yun Liu, Yajun Yang, Jiucun Wang, Yong Zhao, Li Jin, Liang Zhang, Jean Krutmann, Sijia Wang
Summary: Solar lentigines (SLs) are a common sign of aging skin caused by chronic exposure to sunlight and environmental stressors. Recent studies have suggested a possible genetic component, but the findings are inconsistent. Through a multi-trait analysis, researchers discovered that genetic variants in the telomerase reverse transcriptase gene are significantly associated with non-facial SLs in East Asian and Caucasian populations. These variants are also related to facial SLs but not other skin aging or pigmentation traits, highlighting a previously unrecognized role of telomerase reverse transcriptase in lentigines formation.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Article
Genetics & Heredity
Shixiong Tian, Chaofeng Tu, Xiaojin He, Lanlan Meng, Jiaxiong Wang, Shuyan Tang, Yang Gao, Chunyu Liu, Huan Wu, Yiling Zhou, Mingrong Lv, Ge Lin, Li Jin, Yunxia Cao, Dongdong Tang, Feng Zhang, Yue-Qiu Tan
Summary: This study identified biallelic deleterious mutations of CFAP54 in three unrelated men with severe MMAF or NOA. These mutations were associated with abnormal sperm morphology, reduced sperm concentration and motility. Immunofluorescence assays showed reduced staining of four flagellar assembly-associated proteins in the spermatozoa of CFAP54-deficient men.
JOURNAL OF MEDICAL GENETICS
(2023)
Letter
Plant Sciences
Xiao-Min Yang, Hai-Liang Meng, Jian-Lin Zhang, Yao Yu, Edward Allen, Zi-Yang Xia, Kong-Yang Zhu, Pan-Xin Du, Xiao-Ying Ren, Jian-Xue Xiong, Xiao-Yu Lu, Yi Ding, Sheng Han, Wei-Peng Liu, Li Jin, Chuan-Chao Wang, Shao-Qing Wen
JOURNAL OF SYSTEMATICS AND EVOLUTION
(2023)
Article
Biochemistry & Molecular Biology
Hanni Ke, Shuyan Tang, Ting Guo, Dong Hou, Xue Jiao, Shan Li, Wei Luo, Bingying Xu, Shidou Zhao, Guangyu Li, Xiaoxi Zhang, Shuhua Xu, Lingbo Wang, Yanhua Wu, Jiucun Wang, Feng Zhang, Yingying Qin, Li Jin, Zi-Jiang Chen
Summary: Whole-exome sequencing in a cohort of 1,030 patients with POI identified new likely pathogenic variants and revealed different genetic architectures between primary and secondary amenorrhea. This study expands our understanding of the genetic landscape underlying POI and provides insights that have the potential to improve diagnostic genetic screenings.
Article
Oncology
Huangbo Yuan, Tao Qing, Sibo Zhu, Xiaorong Yang, Weicheng Wu, Kelin Xu, Hui Chen, Yanfeng Jiang, Chengkai Zhu, Ziyu Yuan, Tiejun Zhang, Li Jin, Chen Suo, Ming Lu, Xingdong Chen, Weimin Ye
Summary: Defects in DNA damage repair pathways can lead to genomic instability and oncogenesis. DDR alterations in esophageal squamous cell carcinoma (ESCC) affect mutational processes and tumor immune microenvironment.
Article
Genetics & Heredity
Chunyu Liu, Wei Si, Chaofeng Tu, Shixiong Tian, Xiaojin He, Shengnan Wang, Xiaoyu Yang, Chencheng Yao, Cong Li, Zine-Eddine Kherraf, Maosen Ye, Zixue Zhou, Yuhua Ma, Yang Gao, Yu Li, Qiwei Liu, Shuyan Tang, Jiaxiong Wang, Hexige Saiyin, Liangyu Zhao, Liqun Yang, Lanlan Meng, Bingbing Chen, Dongdong Tang, Yiling Zhou, Huan Wu, Mingrong Lv, Chen Tan, Ge Lin, Qingpeng Kong, Hong Shi, Zhixi Su, Zheng Li, Yong-Gang Yao, Li Jin, Ping Zheng, Pierre F. Ray, Yue-Qiu Tan, Yunxia Cao, Feng Zhang
Summary: Primate-specific genes (PSGs) expressed in the brain and testis are consistent with brain evolution in primates. The identification of deleterious variants of the X-linked SSX1 gene in men with asthenoteratozoospermia highlights its crucial role in spermatogenesis. Knocking down Ssx1 expression in non-human primate and tree shrew models resulted in reduced sperm motility and abnormal sperm morphology, reflecting the phenotype observed in humans. This study has important implications for genetic counseling and clinical diagnosis, and provides insights into the functions of testis-enriched PSGs in spermatogenesis.
AMERICAN JOURNAL OF HUMAN GENETICS
(2023)
Article
Neurosciences
Jincheng Li, Sibo Zhu, Yingzhe Wang, Min Fan, Jiacheng Dai, Chengkai Zhu, Kelin Xu, Mei Cui, Chen Suo, Li Jin, Yanfeng Jiang, Xingdong Chen
Summary: By comparing the gut microbiota in a community-based cohort, it was found that bacteria capable of producing SCFAs were positively associated with better cognitive performance. In addition, specific bacterial strains were more abundant in individuals with MCI or CN groups and were correlated with cognitive performance.
NEUROBIOLOGY OF DISEASE
(2023)
Article
Chemistry, Applied
Junyu Luo, Qili Qian, Wenxin Zheng, Ieva Gripkauskaite, Sijie Wu, Min Zhang, Jinxi Li, Bingfei Fu, Ranjit Bhogal, Peter Murray, Matthew Rowson, Bin Li, Xiangyang Xue, Xuelan Gu, Yajun Yang, Li Jin, David Andrew Gunn, Sijia Wang
Summary: This study investigated the extent to which scalp hair parameters change with age in Chinese men and women. The number of hairs per follicular unit was found to have a negative correlation with age in both men and women. Men had a greater number of hairs and follicular units than women on average, but experienced a greater decrease in the number of hairs per follicular unit with age, particularly in multi-hair follicular units. Hair loss was not random across follicular units, and a higher number of hairs per follicular unit increased the risk of hair loss. The results suggest that the presence of multi-hair follicular units on the scalp contributes to the greater susceptibility of scalp hair to hair loss compared to other body sites.
INTERNATIONAL JOURNAL OF COSMETIC SCIENCE
(2023)
Editorial Material
Multidisciplinary Sciences
Yi Li, Meng Hao, Zixin Hu, Yanyun Ma, Kun Wang, Xiaoyu Liu, Xianhong Yin, Menghan Zhang, Yi Wang, Meng Liang, Yuan Guo, Lei Bao, Shixuan Zhang, Shiguan Le, Chenyuan Wu, Dayan Sun, Yang Wei, Fei Wu, Rui Zhang, Lingxian Zhu, Hui Zhang, Shuai Jiang, Xingdong Chen, Xiaofeng Wang, Yao Zhang, Longli Kang, Wenyuan Duan, Bin Qiao, Jiucun Wang, Li Jin
NATIONAL SCIENCE REVIEW
(2023)
Article
Medicine, Research & Experimental
Wenjing Wang, Yoichi Miyamoto, Biaobang Chen, Juanzi Shi, Feiyang Diao, Wei Zheng, Qun Li, Lan Yu, Lin Li, Yao Xu, Ling Wu, Xiaoyan Mao, Jing Fu, Bin Li, Zheng Yan, Rong Shi, Xia Xue, Jian Mu, Zhihua Zhang, Tianyu Wu, Lin Zhao, Weijie Wang, Zhou Zhou, Jie Dong, Qiaoli Li, Li Jin, Lin He, Xiaoxi Sun, Ge Lin, Yanping Kuang, Lei Wang, Qing Sang
Summary: By analyzing whole-exome sequencing data of 606 women with PREMBA, researchers have identified a candidate gene KPNA7, which may contribute to the development of PREMBA. The study further revealed that KPNA7 mutations reduce protein levels, impair its binding capacity to substrate RSL1D1, and affect nuclear transport activity. Furthermore, the study found that mouse KPNA2 plays a critical role in embryonic development and its deficiency leads to embryo arrest, similar to human PREMBA cases. These findings provide a mechanistic understanding of PREMBA and a diagnostic marker for PREMBA patients.
JOURNAL OF CLINICAL INVESTIGATION
(2023)
Article
Genetics & Heredity
Jialin Li, Qingxia Huang, Yingzhe Wang, Mei Cui, Kelin Xu, Chen Suo, Zhenqiu Liu, Yanpeng An, Li Jin, Huiru Tang, Xingdong Chen, Yanfeng Jiang
Summary: Cardiovascular health is linked to a lower risk of cognitive decline, and this association may be mediated by metabolic perturbations. The study found that better cardiovascular health was associated with a lower risk of concentration and orientation decline. Certain blood components, such as apolipoprotein-A1 and high-density lipoprotein cholesterol, were also associated with a lower risk of memory and orientation decline. Mediation analysis suggested that cholesterol ester and total lipids in medium-size HDL may partially mediate the negative association between health status and the risk of orientation decline. These findings highlight the potential of using lipoproteins as targets for early stage dementia screening and intervention.
