Article
Cardiac & Cardiovascular Systems
Veli K. Topkara, Kevin J. Clerkin, Justin A. Fried, Jan Griffin, Jayant Raikhelkar, Sun Hi Lee, Farhana Latif, Marlena Habal, Evelyn Horn, Maryjane A. Farr, Koji Takada, Yoshifumi Naka, Ulrich P. Jorde, Gabriel Sayer, Nir Uriel
Summary: This study analyzed the characteristics and outcomes of waitlisted patients for heart transplant in the US between 2018 and 2020, finding that patients using exception status were more likely to have nonischemic heart failure and blood type O. There were significant variations in exception status utilization across different regions and centers, and listing by exception criteria was associated with a higher incidence of heart transplantation compared to listing by standard criteria.
CIRCULATION-HEART FAILURE
(2021)
Review
Medicine, General & Internal
Daniele Masarone, Michelle M. Kittleson, Piero Pollesello, Marco Marini, Massimo Iacoviello, Fabrizio Oliva, Angelo Caiazzo, Andrea Petraio, Giuseppe Pacileo
Summary: Levosimendan is a drug used for treating heart failure, and it has shown promising results in improving symptoms and clinical status in patients with advanced heart failure with reduced ejection fraction. Levosimendan may also have potential benefits in preventing and treating right ventricular dysfunction after left ventricular assist device implantation, although more evidence is needed. Additionally, scheduled intervals of levosimendan treatment may serve as a bridge to transplant strategy for patients with advanced heart failure.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Michelle M. Kittleson, Amrut V. Ambardekar, Lynne W. Stevenson, Nisha A. Gilotra, Palak Shah, Gregory A. Ewald, Jennifer T. Thibodeau, Josef Stehlik, Maryse Palardy, Jerry D. Estep, Thomas M. Cascino, J. Timothy Baldwin, Neal Jeffries, Shokoufeh Khalatbari, Matheos Yosef, Wendy Taddei Peters, Blair Richards, Douglas L. Mann, Keith D. Aaronson, Garrick C. Stewart
Summary: The study aims to determine the clinical trajectory of ambulatory advanced heart failure patients through early re-assessment and finds that these patients have worse outcomes one year later. Therefore, early reassessment plays a crucial role in informing treatment decisions.
JOURNAL OF HEART AND LUNG TRANSPLANTATION
(2022)
Article
Cardiac & Cardiovascular Systems
Matteo Pagnesi, Carlo Mario Lombardi, Mauro Chiarito, Davide Stolfo, Luca Baldetti, Ferdinando Loiacono, Chiara Tedino, Luca Arrigoni, Daniele Ghiraldin, Daniela Tomasoni, Riccardo Maria Inciardi, Marta Maccallini, Alessandro Villaschi, Gaia Gasparini, Marco Montella, Stefano Contessi, Daniele Cocianni, Maria Perotto, Giuseppe Barone, Marco Merlo, Alberto Maria Cappelletti, Gianfranco Sinagra, Daniela Pini, Marco Metra
Summary: The study evaluated the prognostic impact of the advanced heart failure definition proposed by the Heart Failure Association of the European Society of Cardiology in patients with heart failure, showing that patients meeting this definition had a higher rate of the primary endpoint at 1 year.
EUROPEAN JOURNAL OF HEART FAILURE
(2022)
Article
Cardiac & Cardiovascular Systems
Laura Murphy, Gerard T. Giblin, Neasa Starr, Norma Caples, Regina Black, Carmel Halley, Kenneth McDonald, Emer Joyce
Summary: This study aimed to identify the accurate prevalence data for ambulatory advanced heart failure (HF) in European countries. The survey results showed that approximately 5% of the all-comer routine HF clinic population could be eligible for referral to an advanced HF center for assessment for advanced surgical therapies. The study also found that almost one-quarter of patients in this chronic outpatient population had NYHA III-IV symptoms. These findings are important for resource and service planning.
Article
Cardiac & Cardiovascular Systems
Daniele Masarone, Andrea Petraio, Antonio Fiorentino, Santo Dellegrottaglie, Fabio Valente, Ernesto Ammendola, Gerardo Nigro, Giuseppe Pacileo
Summary: Cardiac contractility modulation (CCM) is a novel device-based therapy that improves the quality of life in heart failure patients. This case report demonstrates the successful use of CCM as a bridge to transplant in a young obese patient with advanced heart failure.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Benedicte Heegaard, Tania Deis, Kasper Rossing, Mads Ersboll, Caroline Kistorp, Finn Gustafsson
Summary: This study aims to investigate the impact of diabetes on hemodynamics in heart failure patients. It found that heart failure patients with diabetes have higher filling pressures, including pulmonary capillary wedge pressure, central venous pressure, cardiac index, and mean arterial pressure. Additionally, poor glycemic control in diabetic patients is associated with higher filling pressures. Therefore, diabetic cardiomyopathy may contribute to the increased mortality in heart failure patients with diabetes, but other unknown mechanisms beyond hemodynamic factors are also likely involved.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Piotr Ponikowski, Robert J. Mentz, Adrian F. Hernandez, Javed Butler, Muhammad Shahzeb Khan, Dirk J. van Veldhuisen, Bernard Roubert, Nicole Blackman, Tim Friede, Ewa A. Jankowska, Stefan D. Anker
Summary: This meta-analysis of intravenous ferric carboxymaltose therapy for iron-deficient heart failure patients found a significantly reduced risk of hospitalizations for HF and cardiovascular causes, with no apparent effect on mortality.
EUROPEAN HEART JOURNAL
(2023)
Review
Medicine, General & Internal
Roger Hullin, Philippe Meyer, Patrick Yerly, Matthias Kirsch
Summary: Mechanical circulatory support and heart transplantation are established surgical options for advanced heart failure treatment. This review summarizes recent advances in surgical treatment options for advanced heart failure and proposes an algorithm for patients over 65 years old.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jianwei Zheng, Islam Abudayyeh, Georgi Mladenov, Daniele Struppa, Guohua Fu, Huimin Chu, Cyril Rakovski
Summary: This study aims to develop an artificial intelligence algorithm that accurately predicts the pulmonary artery pressure waveform using non-invasive signal inputs. The proposed method, combining a residual convolutional network and wavelet scattering transform data preprocessing, achieved the highest coefficient of determination and other performance metrics in the testing cohort.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Matteo Pagnesi, Carlo Mario Lombardi, Chiara Tedino, Mauro Chiarito, Davide Stolfo, Luca Baldetti, Marianna Adamo, Filippo Cali, Riccardo Maria Inciardi, Daniela Tomasoni, Ferdinando Loiacono, Marta Maccallini, Alessandro Villaschi, Gaia Gasparini, Marco Montella, Stefano Contessi, Daniele Cocianni, Maria Perotto, Giuseppe Barone, Marco Merlo, Alberto Maria Cappelletti, Gianfranco Sinagra, Daniela Pini, Marco Metra
Summary: This study aims to assess the prognostic impact of ejection fraction (EF) in patients with advanced heart failure. The results show that EF is still of prognostic value in patients with at least one high-risk marker for advanced heart failure.
Review
Biology
Filippos Triposkiadis, Grigorios Giamouzis, Takeshi Kitai, John Skoularigis, Randall C. Starling, Andrew Xanthopoulos
Summary: Advanced heart failure can occur at different levels of left ventricular ejection fraction, and accurate assessment of LV function and size is crucial for patient management. Traditional treatments may be ineffective, requiring more advanced interventions such as mechanical circulatory support or heart transplantation.
Article
Environmental Sciences
Eleonora Grilli, Roberto Battisti, Fabio Remondino
Summary: The study introduces an advanced photogrammetric pipeline for inspecting apple trees in the field, automatically detecting fruits from videos and quantifying their size and number. By utilizing smartphone-based videos and combining photogrammetry, deep learning, and geometric algorithms, the proposed approach aims to simplify fieldwork for farmers and agronomists while providing more accurate measurements and estimating harvesting dates. Experiment results demonstrate the accuracy and potential of the method, with data, images, code, and network weights available on the 3DOM-FBK GitHub account.
Article
Cardiac & Cardiovascular Systems
Kaushiga Krishnathasan, Konstantinos Dimopoulos, Neill Duncan, Piera Ricci, Alexander Kempny, Isma Rafiq, Michael A. Gatzoulis, Ee Ling Heng, Sarah Blakey, Claudia Montanaro, Sonya Babu-Narayan, Darrel P. Francis, Wei Li, Andrew Constantine
Summary: Renal dysfunction in adults with congenital heart disease (CHD) and heart failure is associated with disease progression, increased diuretic doses, and longer hospital stays. Chronic kidney disease (CKD) is common and triples the risk of death, transplantation, or ventricular assist device. Intensified monitoring, optimization of medical therapy, and collaborative management with renal physicians are necessary in these patients.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2023)
Article
Psychology, Multidisciplinary
Lidia Gazzi, Laura Comini, Simonetta Scalvini, Irene Taccolini, Michele Vitacca
Summary: This study tested the feasibility of telepsychology support for patients with severe cardiorespiratory disease and their caregivers, and explored the relationships between patients' and caregivers' clinical measures. The results showed that telepsychology support was feasible and satisfying, and could improve the quality of life for both patients and caregivers.
FRONTIERS IN PSYCHOLOGY
(2022)
