Beyond the RAAS: dissecting the antifibrotic effects of vitamin D analogues

Maxacalcitol ameliorates tubulointerstitial fibrosis in obstructed kidneys by recruiting PPM1A/VDR complex to pSmad3

(2012) Kazunori Inoue et al.   LABORATORY INVESTIGATION

Angiotensin II as a Morphogenic Cytokine Stimulating Renal Fibrogenesis

(2011) C. Ruster et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Oral cholecalciferol decreases albuminuria and urinary TGF-β1 in patients with type 2 diabetic nephropathy on established renin–angiotensin–aldosterone system inhibition

(2011) Min Jeong Kim et al.   KIDNEY INTERNATIONAL

Vitamin D in Chronic Kidney Disease: New Potential for Intervention

(2010) Katarina Mirkovic et al.   CURRENT DRUG TARGETS

Blockade of Wnt/ -Catenin Signaling by Paricalcitol Ameliorates Proteinuria and Kidney Injury

(2010) W. He et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Vitamin D Receptor Attenuates Renal Fibrosis by Suppressing the Renin-Angiotensin System

(2010) Y. Zhang et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Selective vitamin D receptor activation with paricalcitol for reduction of albuminuria in patients with type 2 diabetes (VITAL study): a randomised controlled trial

(2010) Dick de Zeeuw et al.   LANCET

Possible renoprotection by vitamin D in chronic renal disease: beyond mineral metabolism

(2009) Carolina R. C. Doorenbos et al.   Nature Reviews Nephrology

Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice

(2008) Roger Bouillon et al.   ENDOCRINE REVIEWS

Paricalcitol Inhibits Renal Inflammation by Promoting Vitamin D Receptor-Mediated Sequestration of NF- B Signaling

(2008) X. Tan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Suppression of renin–angiotensin gene expression in the kidney by paricalcitol

(2008) Michael Freundlich et al.   KIDNEY INTERNATIONAL

Vitamin D levels and patient outcome in chronic kidney disease

(2008) Pietro Ravani et al.   KIDNEY INTERNATIONAL

Renal outcomes with telmisartan, ramipril, or both, in people at high vascular risk (the ONTARGET study): a multicentre, randomised, double-blind, controlled trial

(2008) Johannes FE Mann et al.   LANCET

Cell-specific Delivery of a Transforming Growth Factor-beta Type I Receptor Kinase Inhibitor to Proximal Tubular Cells for the Treatment of Renal Fibrosis

(2008) Jai Prakash et al.   PHARMACEUTICAL RESEARCH

Combination therapy with AT1 blocker and vitamin D analog markedly ameliorates diabetic nephropathy: Blockade of compensatory renin increase

(2008) Z. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Renoprotective role of the vitamin D receptor in diabetic nephropathy

(2007) Z. Zhang et al.   KIDNEY INTERNATIONAL