Microfluidics for single-cell genetic analysis

Recent advances in microfluidic cell separations

(2013) Yan Gao et al.   ANALYST

Self-Digitization of Samples into a High-Density Microfluidic Bottom-Well Array

(2013) Thomas Schneider et al.   ANALYTICAL CHEMISTRY

Probing cell–cell communication with microfluidic devices

(2013) Feng Guo et al.   LAB ON A CHIP

Single-cell gene expression analysis reveals genetic associations masked in whole-tissue experiments

(2013) Quin F Wills et al.   NATURE BIOTECHNOLOGY

Quantitative assessment of single-cell RNA-sequencing methods

(2013) Angela R Wu et al.   NATURE METHODS

Smart-seq2 for sensitive full-length transcriptome profiling in single cells

(2013) Simone Picelli et al.   NATURE METHODS

Evaluation of Digital PCR for Absolute RNA Quantification

(2013) Rebecca Sanders et al.   PLoS One

Inertial Focusing for Tumor Antigen-Dependent and -Independent Sorting of Rare Circulating Tumor Cells

(2013) E. Ozkumur et al.   Science Translational Medicine

Capture and Stimulated Release of Circulating Tumor Cells on Polymer-Grafted Silicon Nanostructures

(2012) Shuang Hou et al.   ADVANCED MATERIALS

Sensitive and High-Throughput Isolation of Rare Cells from Peripheral Blood with Ensemble-Decision Aliquot Ranking

(2012) Perry G. Schiro et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Data exploration, quality control and testing in single-cell qPCR-based gene expression experiments

(2012) Andrew McDavid et al.   BIOINFORMATICS

The Origin and Evolution of Mutations in Acute Myeloid Leukemia

(2012) John S. Welch et al.   CELL

Digital LAMP in a sample self-digitization (SD) chip

(2012) Alexander Gansen et al.   LAB ON A CHIP

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

(2012) Li Ding et al.   NATURE

Microfluidic single-cell real-time PCR for comparative analysis of gene expression patterns

(2012) Veronica Sanchez-Freire et al.   Nature Protocols

A programmable droplet-based microfluidic device applied to multiparameter analysis of single microbes and microbial communities

(2012) K. Leung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clonal Evolution of Preleukemic Hematopoietic Stem Cells Precedes Human Acute Myeloid Leukemia

(2012) M. Jan et al.   Science Translational Medicine

High-Throughput Selection, Enumeration, Electrokinetic Manipulation, and Molecular Profiling of Low-Abundance Circulating Tumor Cells Using a Microfluidic System

(2011) Udara Dharmasiri et al.   ANALYTICAL CHEMISTRY

Theoretical Design and Analysis of Multivolume Digital Assays with Wide Dynamic Range Validated Experimentally with Microfluidic Digital PCR

(2011) Jason E. Kreutz et al.   ANALYTICAL CHEMISTRY

Single cell genome sequencing

(2011) Suzan Yilmaz et al.   CURRENT OPINION IN BIOTECHNOLOGY

High-throughput microfluidic single-cell RT-qPCR

(2011) A. K. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Self-Digitization of Sample Volumes

(2010) Dawn E. Cohen et al.   ANALYTICAL CHEMISTRY

A Comprehensive Survey of Clonal Diversity Measures in Barrett's Esophagus as Biomarkers of Progression to Esophageal Adenocarcinoma

(2010) L. M. F. Merlo et al.   Cancer Prevention Research

Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype

(2010) So Yeon Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Whole-genome molecular haplotyping of single cells

(2010) H Christina Fan et al.   NATURE BIOTECHNOLOGY

Single-molecule enzyme-linked immunosorbent assay detects serum proteins at subfemtomolar concentrations

(2010) David M Rissin et al.   NATURE BIOTECHNOLOGY

Review of cell and particle trapping in microfluidic systems

(2009) J. Nilsson et al.   ANALYTICA CHIMICA ACTA

Single-Molecule Approaches to Stochastic Gene Expression

(2009) Arjun Raj et al.   Annual Review of Biophysics

Microfluidic sample preparation: cell lysis and nucleic acid purification

(2009) Jungkyu Kim et al.   Integrative Biology

SlipChip

(2009) Wenbin Du et al.   LAB ON A CHIP

High-Efficiency Single-Cell Entrapment and Fluorescence in Situ Hybridization Analysis Using a Poly(dimethylsiloxane) Microfluidic Device Integrated with a Black Poly(ethylene terephthalate) Micromesh

(2008) Tadashi Matsunaga et al.   ANALYTICAL CHEMISTRY

Controlled encapsulation of single-cells into monodisperse picolitre drops

(2008) Jon F. Edd et al.   LAB ON A CHIP

Dropspots: a picoliter array in a microfluidic device

(2008) Christian H. J. Schmitz et al.   LAB ON A CHIP

Direct multiplexed measurement of gene expression with color-coded probe pairs

(2008) Gary K Geiss et al.   NATURE BIOTECHNOLOGY