Article
Environmental Sciences
Shuowen Yang, Xiang Yan, Hanlin Qin, Qingjie Zeng, Yi Liang, Henry Arguello, Xin Yuan
Summary: This paper introduces a novel mid-infrared compressive hyperspectral imaging system that combines an improved MIR-DMD with an off-the-shelf infrared spectroradiometer to capture hyperspectral images in the mid-infrared spectral range. The development of a dual-stage image reconstruction method and the use of measurement without coding as side information has improved the quality of reconstruction for infrared hyperspectral images. This system represents a less expensive alternative to conventional mid-infrared hyperspectral imaging systems.
Article
Chemistry, Multidisciplinary
Junyao Wang, Xingyu Chen, Huan Liu, Yunpeng Li, Tianhong Lang, Rui Wang, Bowen Cui, Weihua Zhu
Summary: This paper presents a helical three-dimensional passive micromixer fabricated through 3D printing and polymer dissolution technology, which effectively improves the mixing efficiency according to experimental results.
Article
Chemistry, Analytical
Hamid Aghamohammadi, Seied Ali Hosseini, Sanjana Srikant, Alexander Wong, Mahla Poudineh
Summary: This paper introduces a computational model for the rational design and optimization of immunobead-based assays in microfluidic mixing channels. The model examines various factors affecting the efficiency of analyte capture on the surface of microbeads and is validated experimentally. It can be adapted to a wide range of target molecules and different device designs.
ANALYTICAL CHEMISTRY
(2022)
Article
Mechanics
Shuai Yuan, Mingyong Zhou, Tao Peng, Qiang Li, Fengze Jiang
Summary: This article introduces a novel planar mixer with staggered Z-shaped baffles and evaluates its mixing ability through numerical investigations. The results show that the mixer achieves high mixing efficiency within a certain range of Reynolds numbers, and different vortex patterns can improve the mixing quality.
Article
Optics
Farid Ullah Khan, Aldo Moreno-Oyervides, Oscar Elias Bonilla-Manrique, Pedro Martin-Mateos
Summary: High-performance hyperspectral imaging is in high demand due to its wide range of capabilities. However, traditional systems have limitations in resolving narrow spectral features. In this study, we introduce the first hyperspectral dual-comb imaging system with sub-GHz optical resolutions and fast acquisition rates in the mid-infrared region.
OPTICS AND LASERS IN ENGINEERING
(2023)
Article
Medicine, Research & Experimental
Matthew N. O'Brien N. Laramy, Antonio P. Costa, Yareli Maciel Cebrero, Johnson Joseph, Apoorva Sarode, Nanzhi Zang, Lee Joon Kim, Kate Hofmann, Shirley Wang, Alexandre Goyon, Stefan G. Koenig, Michal Hammel, Greg L. Hura
Summary: This article systematically investigates how the mixer technology used to form lipid nanoparticles (LNPs) influences LNP structure. The study compares a coaxial turbulent jet mixer and a staggered herringbone microfluidic mixer. Results show that LNPs generated with the coaxial turbulent jet mixer are consistently smaller, have a narrower particle size distribution, and have a higher encapsulation rate compared to the microfluidic mixer, but have a greater variation in internal structure with less ordered cores. Similar trends are observed for mRNA-LNPs produced by the coaxial turbulent jet mixer, but with more frequent bleb features.
MOLECULAR PHARMACEUTICS
(2023)
Article
Materials Science, Characterization & Testing
Robert Zimmerleiter, Ramin Nikzad-Langerodi, Cyril Ruckebusch, Matthias Godejohann, Jakob Kilgus, Kristina Duswald, Markus Brandstetter
Summary: In this study, mid-infrared hyperspectral images of multilayer polymer film (MLPF) cross sections were analyzed using different data analysis techniques. While pure band integration and PCA were affected by common physical artifacts, MCR provided a clear picture of the composition of the MLPF, guiding the way for spatially resolved polymer analysis using high-performance mid-infrared spectroscopic instrumentation.
Article
Biochemical Research Methods
Matteo Antognoli, Daniel Stoecklein, Chiara Galletti, Elisabetta Brunazzi, Dino Di Carlo
Summary: This study optimized mixing efficiency by analyzing sequences of cylindrical obstacles in the inertial regime, predicted and optimized interfacial stretching of co-flowing fluids using a specialized software, and tested new passive mixer designs using confocal microscopy and CFD simulations, achieving mixing efficiencies around 80%.
Article
Chemistry, Applied
Jose Manuel Amigo, Birthe Moller Jespersen, Frans van den Berg, Jorgen Juul Jensen, Soren B. Engelsen
Summary: The Danish buttered cookie is a well-known confectionery product that is produced using batch-wise and continuous dough mixing methods. This study analyzed the physicochemical differences of the cookies after baking and found that the changes in texture between the two production methods are mainly attributed to the difference in crystalline sucrose and the presence of migrated butter-fat spots on the surface of the cookies in continuous production. Near Infrared hyperspectral imaging and Chemometrics were used to conduct the analysis.
Article
Multidisciplinary Sciences
Alexander Ebner, Paul Gattinger, Ivan Zorin, Lukas Krainer, Christian Rankl, Markus Brandstetter
Summary: In this study, a wide-field hyperspectral mid-infrared microscope based on multidimensional single-pixel imaging was demonstrated. The microscope utilized a high brightness MIR supercontinuum source for sample illumination and a single micro-opto-electro-mechanical digital micromirror device (DMD) for spatial and spectral differentiation. The DMD served the purpose of masking captured scenes and dispersing the projected field for wavelength selection without additional optical elements. The microscope's imaging and spectral capabilities were characterized, achieving high spatial and spectral resolutions. Label-free chemical imaging and examination of polymer compounds and red blood cells were successfully demonstrated. The design showed improved sample throughput in MIR chemical and biomedical imaging with tunable field of view and adjustable spatial resolution.
SCIENTIFIC REPORTS
(2023)
Article
Chemistry, Analytical
Juan Melendez, Guillermo Guarnizo
Summary: An imaging Fourier-transform spectrometer was used to acquire transmittance spectra of atmospheric pollutants with known column densities. Principal component analysis was utilized to reconstruct gas spectra with high fidelity, improve signal-to-noise ratio, and speed up retrieval process significantly. Retrieval can be further simplified by obtaining T and Q as quadratic functions of the first two principal components.
Review
Chemistry, Inorganic & Nuclear
Miae Won, Mingle Li, Hyeong Seok Kim, Pai Liu, Seyoung Koo, Subin Son, Jae Hong Seo, Jong Seung Kim
Summary: Fluorescence imaging is a crucial optical technique for visualizing dynamic biological processes using light signals from molecules, cells, and living organisms. Recent breakthroughs have increased opportunities to generate multifunctional fluorescence probes for highly accurate diagnosis of early-stage cancers. The article reviews recent advances in small molecule-based fluorescence probes and their design principles, while highlighting current challenges and opportunities in the field.
COORDINATION CHEMISTRY REVIEWS
(2021)
Article
Engineering, Electrical & Electronic
David Z. Ting, Sir B. Rafol, Arezou Khoshakhlagh, Sam A. Keo, Alexander Soibel, Anita M. Fisher, Brian J. Pepper, Cory J. Hill, Sarath D. Gunapala, Thomas S. Pagano
Summary: In this study, InAs/InAsSb type-II strained layer superlattice high-operating temperature barrier infrared detector (HOT-BIRD) focal plane arrays (FPAs) were fabricated for midwavelength infrared hyperspectral imaging applications. The FPA demonstrated high mean quantum efficiency and low dark current density in the 3-5μm band, with low noise equivalent differential temperature (NEDT) and high NEDT operability.
IEEE PHOTONICS TECHNOLOGY LETTERS
(2022)
Article
Energy & Fuels
Shipra Verma, Siddhartha Panda
Summary: This study systematically investigates the influence of 3-dimensional geometries on flow transport in microfluidic immunosensors and presents novel scientific results for designing efficient heterogeneous immunosensors.
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2022)
Article
Chemistry, Analytical
Ryo Kato, Taka-aki Yano, Takeo Minamikawa, Takuo Tanaka
Summary: Visualizing the spatial distribution of chemical compositions in biological tissues is crucial for studying biological processes and diseases. In this study, we demonstrated the chemical imaging of heart tissues using mid-infrared photothermal microscopy, which provides high sensitivity and spatial resolution for observing different biomolecules.
ANALYTICAL SCIENCES
(2022)
Article
Engineering, Electrical & Electronic
Drew P. Kise, Michael J. Reddish, R. Brian Dyer
JOURNAL OF MICROMECHANICS AND MICROENGINEERING
(2015)
Article
Biochemistry & Molecular Biology
Michael J. Reddish, Morgan B. Vaughn, Rong Fu, R. Brian Dyer
Article
Spectroscopy
Caitlin M. Davis, Michael J. Reddish, R. Brian Dyer
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2017)
Article
Chemistry, Multidisciplinary
Leah C. Williams, Michael J. Reddish
JOURNAL OF CHEMICAL EDUCATION
(2018)
Article
Biochemistry & Molecular Biology
Natalya N. Degtyareva, Courtney A. Barber, Michael J. Reddish, Jeffrey T. Petty
Article
Chemistry, Physical
Michael J. Reddish, Huo-Lei Peng, Hua Deng, Kunal S. Panwar, Robert Callender, R. Brian Dyer
JOURNAL OF PHYSICAL CHEMISTRY B
(2014)
Article
Biochemical Research Methods
Kelly S. Burke, Dzmitry Parul, Michael J. Reddish, R. Brian Dyer
Article
Biochemistry & Molecular Biology
F. Peter Guengerich, Clayton J. Wilkey, Sarah M. Glass, Michael J. Reddish
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Michael J. Reddish, F. Peter Guengerich
JOURNAL OF BIOLOGICAL CHEMISTRY
(2019)
Article
Biochemistry & Molecular Biology
Sarah M. Glass, Michael J. Reddish, Stella A. Child, Clayton J. Wilkey, Donald F. Stec, F. Peter Guengerich
Summary: The paragraph discusses the catalytic activities of cytochrome P450 (P450) 11B1 and 11B2 in hydroxylation reactions of 11-deoxycorticosterone, with P450 11B2 being involved in the formation of aldosterone. The study also explores the precursor of 11-oxygenated androgens. In experiments, it was found that P450 11B2 can catalyze the hydroxylation reactions of different substrates.
JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Stella A. Child, Michael J. Reddish, Sarah M. Glass, Margo H. Goldfarb, Ian R. Barckhausen, F. Peter Guengerich
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2020)
Article
Biophysics
Michael J. Reddish, Robert Callender, R. Brian Dyer
BIOPHYSICAL JOURNAL
(2017)
Meeting Abstract
Chemistry, Multidisciplinary
Michael J. Reddish, Brian Dyer
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)
Meeting Abstract
Chemistry, Multidisciplinary
Michael J. Reddish, Brian Dyer
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY
(2014)