The effects of pharmacological modulation of the serotonin 2C receptor on goal-directed behavior in mice

A novel strategy for dissecting goal-directed action and arousal components of motivated behavior with a progressive hold-down task.

(2015) Matthew R. Bailey et al.   BEHAVIORAL NEUROSCIENCE

Evidence for a role of 5-HT2C receptors in the motor aspects of performance, but not the efficacy of food reinforcers, in a progressive ratio schedule

(2014) G. Bezzina et al.   PSYCHOPHARMACOLOGY

Measuring reinforcement learning and motivation constructs in experimental animals: Relevance to the negative symptoms of schizophrenia

(2013) Athina Markou et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Dopaminergic Mechanisms of Individual Differences in Human Effort-Based Decision-Making

(2012) M. T. Treadway et al.   JOURNAL OF NEUROSCIENCE

Evaluation of chemically diverse 5-HT2C receptor agonists on behaviours motivated by food and nicotine and on side effect profiles

(2012) G. A. Higgins et al.   PSYCHOPHARMACOLOGY

Pharmacologic Rescue of Motivational Deficit in an Animal Model of the Negative Symptoms of Schizophrenia

(2011) Eleanor H. Simpson et al.   BIOLOGICAL PSYCHIATRY

Selective serotonin 5-HT2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues

(2011) Kathryn A. Cunningham et al.   NEUROPHARMACOLOGY

Anticipatory vs. consummatory pleasure: What is the nature of hedonic deficits in schizophrenia?

(2011) Gregory P. Strauss et al.   PSYCHIATRY RESEARCH

Reconsidering anhedonia in depression: Lessons from translational neuroscience

(2010) Michael T. Treadway et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Apathy in Neuropsychiatric Disease: Diagnosis, Pathophysiology, and Treatment

(2010) Thomas N. Chase   NEUROTOXICITY RESEARCH

Genetic and pharmacological evidence that 5-HT2C receptor activation, but not inhibition, affects motivation to feed under a progressive ratio schedule of reinforcement

(2010) Paul J. Fletcher et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Goal Representations and Motivational Drive in Schizophrenia: The Role of Prefrontal-Striatal Interactions

(2010) D. M. Barch et al.   SCHIZOPHRENIA BULLETIN

Apathy is associated with executive functioning in first episode psychosis

(2009) Ann Faerden et al.   BMC Psychiatry

Characterizing the effects of 5-HT2C receptor ligands on motor activity and feeding behaviour in 5-HT2C receptor knockout mice

(2009) Paul J. Fletcher et al.   NEUROPHARMACOLOGY

Effects of a Cannabinoid1 Receptor Antagonist and Serotonin2C Receptor Agonist Alone and in Combination on Motivation for Palatable Food: A Dose-Addition Analysis Study in Mice

(2008) S. J. Ward et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Emotional Experience in Patients With Schizophrenia Revisited: Meta-analysis of Laboratory Studies

(2008) A. S. Cohen et al.   SCHIZOPHRENIA BULLETIN