Interaction of brain 5-HT synthesis deficiency, chronic stress and sex differentially impact emotional behavior in Tph2 knockout mice

Sex Differences in Corticotropin-Releasing Factor Receptor-1 Action Within the Dorsal Raphe Nucleus in Stress Responsivity

(2013) Alexis R. Howerton et al.   BIOLOGICAL PSYCHIATRY

Microglial activation, increased TNF and SERT expression in the prefrontal cortex define stress-altered behaviour in mice susceptible to anhedonia

(2013) Yvonne Couch et al.   BRAIN BEHAVIOR AND IMMUNITY

Suppression of Serotonin Neuron Firing Increases Aggression in Mice

(2013) E. Audero et al.   JOURNAL OF NEUROSCIENCE

Serotonin Is Required for Exercise-Induced Adult Hippocampal Neurogenesis

(2013) F. Klempin et al.   JOURNAL OF NEUROSCIENCE

Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice

(2013) Christinna V. Jørgensen et al.   NEUROSCIENCE LETTERS

Stress-related Serotonergic Systems: Implications for Symptomatology of Anxiety and Affective Disorders

(2012) Matthew W. Hale et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

GABA concentration and GABAergic neuron populations in limbic areas are differentially altered by brain serotonin deficiency in Tph2 knockout mice

(2012) Jonas Waider et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Genetic depletion of brain 5HT reveals a common molecular pathway mediating compulsivity and impulsivity

(2012) Mariana Angoa-Pérez et al.   JOURNAL OF NEUROCHEMISTRY

Serotonin in the Modulation of Neural Plasticity and Networks: Implications for Neurodevelopmental Disorders

(2012) Klaus-Peter Lesch et al.   NEURON

Impacts of Brain Serotonin Deficiency following Tph2 Inactivation on Development and Raphe Neuron Serotonergic Specification

(2012) Lise Gutknecht et al.   PLoS One

Exaggerated aggression and decreased anxiety in mice deficient in brain serotonin

(2012) V Mosienko et al.   Translational Psychiatry

The stress-coping (mis)match hypothesis for nature×nurture interactions

(2011) Judith R. Homberg   BRAIN RESEARCH

Glucocorticoid-mediated nycthemeral and photoperiodic regulation of tph2 expression

(2011) Laurent Nexon et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

A Genetically Defined Morphologically and Functionally Unique Subset of 5-HT Neurons in the Mouse Raphe Nuclei

(2011) V. Kiyasova et al.   JOURNAL OF NEUROSCIENCE

Stress and anxiety: Structural plasticity and epigenetic regulation as a consequence of stress

(2011) Bruce S. McEwen et al.   NEUROPHARMACOLOGY

Investigation of a central nucleus of the amygdala/dorsal raphe nucleus serotonergic circuit implicated in fear-potentiated startle

(2011) B.M. Spannuth et al.   NEUROSCIENCE

Adult Raphe-Specific Deletion of Lmx1b Leads to Central Serotonin Deficiency

(2011) Ning-Ning Song et al.   PLoS One

Tryptophan hydroxylase-2 (TPH2) in disorders of cognitive control and emotion regulation: A perspective

(2011) Jonas Waider et al.   PSYCHONEUROENDOCRINOLOGY

Dimensions of Depression and Anxiety and the Hypothalamo-Pituitary-Adrenal Axis

(2010) Klaas J. Wardenaar et al.   BIOLOGICAL PSYCHIATRY

Sex Differences in the Serotonergic Influence on the Hypothalamic-Pituitary-Adrenal Stress Axis

(2010) Nirupa Goel et al.   ENDOCRINOLOGY

Widespread hypothalamic-pituitary-adrenocortical axis-relevant and mood-relevant effects of chronic fluoxetine treatment on glucocorticoid receptor gene expression in mice

(2010) Willem Heydendael et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cortisol plasma levels in social anxiety disorder patients correlate with serotonin-1A receptor binding in limbic brain regions

(2010) Rupert Lanzenberger et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood

(2009) Friederike Jansen et al.   BEHAVIOURAL BRAIN RESEARCH

A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure

(2009) Vijay K. Yadav et al.   CELL

Selective activation of dorsal raphe nucleus-projecting neurons in the ventral medial prefrontal cortex by controllable stress

(2009) Michael V. Baratta et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Spatio-temporal expression of tryptophan hydroxylase isoforms in murine and human brain: Convergent data from Tph2 knockout mice

(2009) Lise Gutknecht et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Protective actions of ovarian hormones in the serotonin system of macaques

(2009) Cynthia L. Bethea et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Predictable chronic mild stress improves mood, hippocampal neurogenesis and memory

(2009) V K Parihar et al.   MOLECULAR PSYCHIATRY

Growth retardation and altered autonomic control in mice lacking brain serotonin

(2009) N. Alenina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The vicious cycle towards violence: focus on the negative feedback mechanisms of brain serotonin neurotransmission

(2009) Sietse de Boer   Frontiers in Behavioral Neuroscience

Deficiency of brain 5-HT synthesis but serotonergic neuron formation in Tph2 knockout mice

(2008) Lise Gutknecht et al.   JOURNAL OF NEURAL TRANSMISSION

Exposure to an open-field arena increases c-Fos expression in a subpopulation of neurons in the dorsal raphe nucleus, including neurons projecting to the basolateral amygdaloid complex

(2008) M.W. Hale et al.   NEUROSCIENCE

Corticosteroid–serotonin interactions in the neurobiological mechanisms of stress-related disorders

(2008) Laurence Lanfumey et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Genetic Disruption of Both Tryptophan Hydroxylase Genes Dramatically Reduces Serotonin and Affects Behavior in Models Sensitive to Antidepressants

(2008) Katerina V. Savelieva et al.   PLoS One

Enhanced contextual fear memory in central serotonin-deficient mice

(2008) J.-X. Dai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of GSK3  in behavioral abnormalities induced by serotonin deficiency

(2008) J.-M. Beaulieu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The HPA axis in major depression: classical theories and new developments

(2008) Carmine M. Pariante et al.   TRENDS IN NEUROSCIENCES