Article
Engineering, Multidisciplinary
Dan Liu, Jiajun Qiu, Ru Xu, Junyu Liu, Jiayin Feng, Liping Ouyang, Shi Qian, Yuqin Qiao, Xuanyong Liu
Summary: The BPP hydrogel is a highly stretchable, biocompatible, and antibacterial dressing that exhibits excellent wound closure effectiveness, offering complete protection even in special scenarios. The research demonstrates the potential and clinical applicability of the BPP hydrogel in wound healing.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Qi Zhang, Miao Zhang, Teng Wang, Xiangyan Chen, Quancai Li, Xia Zhao
Summary: Maintaining a moist and sterile environment is beneficial for wound healing. A novel natural multifunctional hydrogel, combining Aloe polysaccharide (AP) and honey, was prepared for infected wound healing. The hydrogel exhibited good water retention capacity, antibacterial activity, and accelerated the healing of infected wounds.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Polymer Science
Hitesh Chopra, Shabana Bibi, Sandeep Kumar, Muhammad Saad Khan, Pradeep Kumar, Inderbir Singh
Summary: In this study, chitosan/polyvinyl alcohol (PVA)-based hydrogel films loaded with honey were developed for potential wound healing applications. The films were evaluated for their physical and mechanical properties, as well as their antimicrobial performance against Staphylococcus aureus. The results demonstrated the potential of these films as wound dressings and suggested the need for further in vivo experiments to evaluate their clinical efficacy.
Article
Biochemistry & Molecular Biology
Muhammad Hasnain, Tasmina Kanwal, Khadija Rehman, Syed Raza Ur Rehman, Shazmeen Aslam, Talat Roome, Samina Perveen, Midhat Batool Zaidi, Salim Saifullah, Saira Yasmeen, Anwarul Hasan, Muhammad Raza Shah
Summary: Wound healing is a complex process that may be delayed by failures in any stage. This study focused on the design and development of CUR-loaded MNs to improve wound healing and antibacterial activity. The results showed that CUR-loaded MNs had increased antioxidant activity and sustained drug release behavior. The improved wound healing potential was demonstrated through tissue regeneration and collagen deposition, suggesting the potential of these MNs as an effective carrier for wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Polymer Science
Kimia Kabirian Kholghi, Pari Tamri, Rasool Haddadi, Shabnam Pourmoslemi
Summary: In this study, a novel polyvinyl alcohol-sodium alginate hydrogel incorporated with ellagic acid loaded nanospheres was prepared. The ellagic acid was loaded into polymeric nanospheres using a double-emulsion solvent evaporation technique, which were then dispersed in a polyvinyl alcohol-sodium alginate hydrogel. The hydrogel exhibited sustained-release profile of ellagic acid and promoted cell proliferation and wound closure.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Materials Science, Multidisciplinary
Proma Bhattacharya, Moumita Kundu, Subhayan Das, Yash Verma, Mahitosh Mandal, Sudarsan Neogi
Summary: This study developed a nanocomposite hydrogel for wound healing by incorporating magnesium oxide nanoparticles, which significantly improved the properties of the hydrogel and demonstrated good biocompatibility and stimulated cell growth.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Biochemistry & Molecular Biology
Fahad M. Aldakheel, Dalia Mohsen, Marwa M. El Sayed, Khaled Ali Alawam, AbdulKarim S. Binshaya, Shatha A. Alduraywish
Summary: In this study, silver nanoparticle composites were synthesized using green tea leaf extract as a reducing agent and microwave irradiation technology. The AgNPs/chitosan grafted polyvinyl alcohol hydrogel samples were successfully prepared. The antibacterial activity and wound-healing ability of the hydrogel samples were evaluated in vitro and in vivo, and promising results were obtained.
Article
Polymer Science
Yan Chu, Shuo Chai, Fei Li, Cuiyan Han, Xiaoyu Sui, Tingting Liu
Summary: This study simulated the hot spring effect using a thermosensitive hydrogel loaded with copper sulfide nanoparticles. By combining it with a nanofiber membrane to mimic the extracellular matrix structure, the wound healing ability was significantly improved. The results suggest that this combined application approach holds promise as a wound treatment strategy.
Article
Polymer Science
Hamide Hemati, Fateme Haghiralsadat, Mahdie Hemati, Ghasem Sargazi, Nastaran Razi
Summary: In this study, a nanoliposome-loaded hydrogel scaffold system was proposed for treating skin injuries. The system exhibited high drug entrapment efficiency and gradual drug release characteristics, with low toxicity to human cells, suggesting its potential in wound healing.
Review
Polymer Science
Pavel Yudaev, Yaroslav Mezhuev, Evgeniy Chistyakov
Summary: This review examines the use of dressings containing nanoparticles for wound repair and evaluates their antimicrobial effects and healing actions. The analysis of 31 sources published between 2021 and 2022 demonstrates a trend towards the development of modern antibacterial wound-healing nanomaterials.
Article
Biochemistry & Molecular Biology
Hengji Zhao, Yushu Zhang, Chao Zhou, Chunling Zhang, Bo Liu
Summary: Natural polysaccharide-based hydrogels provide effective skin protection during trauma and exhibit good antibacterial properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Biochemistry & Molecular Biology
Nahideh Asadi, Hamidreza Pazoki-Toroudi, Azizeh Rahmani Del Bakhshayesh, Abolfazl Akbarzadeh, Soodabeh Davaran, Nasim Annabi
Summary: Hydrogels are widely used for wound healing applications due to their similarity to the native extracellular matrix and ability to provide a moist environment. However, lack of multifunctionality and low mechanical properties may limit their ability to support skin tissue regeneration. Incorporating various biomaterials and nanostructures is an emerging approach to develop multifunctional hydrogels for wound healing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Multidisciplinary
Yanan Jiang, Xin Zhang, Wei Zhang, Menghao Wang, Liwei Yan, Kefeng Wang, Lu Han, Xiong Lu
Summary: A skin-friendly adhesive hydrogel patch based on protein-polyphenol complexation strategy is presented. The hydrogel exhibits a thermoresponsive network and can be activated upon contact with warm skin, while painless detachment can be achieved by placing an ice bag on the surface. The hydrogel also has immunomodulatory performance and can prevent irritation and allergic reactions during long-period contact with the skin.
Article
Engineering, Electrical & Electronic
Fenjing Wang, Kejian Chen, Xuran Yi, Yang Shen, Yanni Lin, Zheqi Zhou
Summary: Self-healing memristor devices were fabricated using a cost-effective and structurally uncomplicated hydrogel. The device is environmentally friendly, biocompatible, has a good switching ratio, stable performance under long-term operation, and can mimic learning and forgetting functions. Furthermore, the device can self-heal at room temperature, making it highly promising for bioelectronics, data storage, and data encryption.
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
(2023)
Article
Biochemistry & Molecular Biology
Syafira Masri, Manira Maarof, Nor Fatimah Mohd, Yosuke Hiraoka, Yasuhiko Tabata, Mh Busra Fauzi
Summary: This study aimed to characterize a crosslinked gelatin-PVA hydrogel with genipin, which exhibited excellent physicochemical, mechanical, and biocompatibility properties, making it a potential bioink for chronic wound healing.
