Article
Medicine, General & Internal
Ari Shinojima, Yoko Ozawa, Atsuro Uchida, Norihiro Nagai, Hajime Shinoda, Toshihide Kurihara, Misa Suzuki, Sakiko Minami, Kazuno Negishi, Kazuo Tsubota
Summary: This study assessed the HFF in CSC using different imaging techniques and found that NIR-AF was the easiest method to detect HFF on late-phase ICGA, which may indicate melanin abnormalities in the retinal pigment epithelium.
JOURNAL OF CLINICAL MEDICINE
(2021)
Review
Chemistry, Medicinal
Stefano Da Pozzo, Pierluigi Iacono, Alessandro Arrigo, Maurizio Battaglia Parodi
Summary: Central serous chorioretinopathy (CSC) is a contentious disease involving various eye structures, with multiple therapeutic options available. Imaging plays a crucial role in evaluating and guiding treatment, while biomarkers serve as diagnostic and prognostic reference points.
Article
Ophthalmology
Alessandro Arrigo, Emanuela Aragona, Alessandro Bordato, Alessandro Calamuneri, Alessio Grazioli Moretti, Stefano Mercuri, Francesco Bandello, Maurizio Battaglia Parodi
Summary: The study aimed to differentiate acute central serous chorioretinopathy (CSC) subtypes by using multimodal imaging. Two main subtypes, retinal pigment epithelium-related CSC (RPE-CSC) and choroidal-related CSC (choroidal-CSC), were identified based on quantitative pachychoroid cutoff values, showing differing responses to treatment and development of macular neovascularization (MNV).
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2021)
Article
Medicine, General & Internal
Elodie Bousquet, Julien Provost, Marta Zola, Richard F. Spaide, Chadi Mehanna, Francine Behar-Cohen
Summary: In patients with central serous chorioretinopathy (CSCR), mid-phase hyperfluorescent plaques (MPHP) were detected in 59.4% of eyes. MPHP were associated with a chronic form of the disease, the presence of irregular pigment epithelium detachments (PED) and changes in the retinal pigment epithelium (RPE) seen on FA.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Multidisciplinary Sciences
Joon Seo Lim, Cheolwon Moon, Junyeop Lee
Summary: The presence of subretinal fluid (SRF) in eyes with central serous chorioretinopathy (CSC) is associated with disturbances in retinal blood flow, including reduced venous blood flow velocity and rate, as well as changes in venous diameter. SRF thickness is correlated with a decrease in venous blood flow rate, suggesting that SRF plays a role in altering retinal blood flow dynamics.
SCIENTIFIC REPORTS
(2022)
Article
Ophthalmology
Jay Chhablani, Francine Behar-Cohen
Summary: The study validated a recently described classification system for central serous chorioretinopathy (CSCR) and assessed the agreement levels among 10 retina physicians. Moderate agreement was found among the graders, with significant differences observed in grading when information on the affected eye was lacking. Further refinement of the classification system and inclusion of information from both eyes may be necessary based on the results.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Qiaozhu Zeng, Yuou Yao, Siying Li, Zhi Yang, Jinfeng Qu, Mingwei Zhao
Summary: This study compared the results of swept-source optical coherence tomography angiography (SS-OCTA) and indocyanine green angiography (ICGA) in patients with central serous chorioretinopathy (CSC). It was found that the coarse granulated high reflective area in SS-OCTA corresponded well with the hyperpermeability area in ICGA. Therefore, SS-OCTA can be used as a non-invasive method for visualizing and quantifying choroidal vasculature in CSC patients.
Article
Ophthalmology
Monica Ravenstijn, Elon H. C. van Dijk, Annechien E. G. Haarman, Talia R. Kaden, Koenraad A. Vermeer, Camiel J. F. Boon, Lawrence A. Yannuzzi, Caroline C. W. Klaver, Suzanne Yzer
Summary: This study compared myopic patients with central serous chorioretinopathy (CSC) to emmetropic patients with CSC and myopic, non-CSC patients. It found that myopic CSC presents similar imaging and clinical characteristics as emmetropic CSC, except for thinner choroids. Other imaging characteristics may aid in the diagnostic process considering the structural changes of myopia.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Ophthalmology
Seongyong Jeong, Wonki Kang, Donghyoun Noh, Jano van Hemert, Min Sagong
Summary: This study investigated choroidal vascular alterations in patients with central serous chorioretinopathy (CSC) using ultra-widefield indocyanine green angiography. The results suggest that CSC patients have larger choroidal vascular hyperpermeability areas, thicker choroids, and more engorged vortex veins compared to controls.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2022)
Article
Ophthalmology
Jie Hu, Jinfeng Qu, Mengyang Li, Guosheng Sun, Zhenyu Piao, Zhiqiao Liang, Yuou Yao, SriniVas Sadda, Mingwei Zhao
Summary: In patients with acute central serous chorioretinopathy, optical coherence tomography angiography-guided PDT was shown to be noninferior to ICGA-guided PDT for resolving subretinal fluid at 3 months, but not at 1 month.
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES
(2021)
Article
Medicine, General & Internal
Rita Serra, Antonio Pinna, Francine Behar-Cohen, Florence Coscas
Summary: This study investigated the incidence and features of choroidal neovascularization (CNV) in central serous chorioretinopathy (CSCR) patients using optical coherence tomography angiography (OCT-A). Complex CSCR is often complicated by type 1 CNV and polypoidal choroidal vasculopathy (PCV) with similar neovascular architecture, suggesting they may be different stages of the same neovascular process. Future studies incorporating demographic data, imaging morphology, and treatment response are needed for definitive conclusions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Ophthalmology
Thomas J. van Rijssen, Elon H. C. van Dijk, Paula Scholz, Robert E. MacLaren, Sascha Fauser, Susan M. Downes, Carel B. Hoyng, Camiel J. F. Boon
Summary: The study evaluated the clinical outcomes after half-dose PDT in cCSC patients with pre-existing fovea-involving atrophy. It found that anatomical changes may occur after treatment, but functional improvements are limited. Early treatment with half-dose PDT before the occurrence of such atrophy is recommended to optimize outcomes.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Ophthalmology
F. Kianersi, M. Masjedi, H. Razmjoo, H. Ghanbari, F. Fazel, A. Dehghani, M. Akhlaghi, A. Salehi, A. Baghi, M. Pourazizi
Summary: The study compared the application of FA and ICGA in imaging CSC patients, showing consistent leakage points between FA and ICGA, but differences in leakage size and chronicity. This suggests that FA could be considered an alternative ocular imaging technology for guiding PDT in CSC patients.
JOURNAL FRANCAIS D OPHTALMOLOGIE
(2022)
Article
Ophthalmology
Enrico Borrelli, Chiara Vigano, Marco Battista, Riccardo Sacconi, Carlotta Senni, Lea Querques, Domenico Grosso, Francesco Bandello, Giuseppe Querques
Summary: This study assessed the diagnostic accuracy of individual and combined imaging modalities for the detection of CNV in CSC. The results showed that OCTA had a higher diagnostic accuracy in identifying CNV than other imaging modalities. The combination of ICGA and structural OCT also achieved comparable diagnostic efficiency.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Gastroenterology & Hepatology
Hong-min Ahn, Gyung Mo Son, In Young Lee, Sang-Ho Park, Nam Su Kim, Kwang-Ryul Baek
Summary: This study aimed to evaluate the extrinsic effects of conditional factors affecting quantitative parameters in ICG angiography, and to establish the optimization through in vitro experiments and a prospective observational study. The study found that various conditional factors such as camera distance, fluorescence emission source, and ICG mode significantly influenced the quantitative parameters of ICG angiography. Standardized protocols, such as using ICG specific modes with a constant distance of 4-5 cm, were recommended to provide optimized fluorescence images.
COLORECTAL DISEASE
(2021)
