Article
Obstetrics & Gynecology
Kemi M. Doll, Annie Green Howard, Till Sturmer, Tim Carey, Wanda K. Nicholson, Erin Carey, Evan Myers, David Nerenz, Whitney R. Robinson
Summary: This study aimed to demonstrate a method for using electronic health record-derived data to create composite symptom severity indices to more fully capture relevant markers that influence the decision for hysterectomy.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Gastroenterology & Hepatology
Irina Midenfjord, Adam Borg, Hans Tornblom, Magnus Simren
Summary: This study found that psychological alterations are common in patients with irritable bowel syndrome (IBS) and there is often overlap among various psychological factors. Five psychological factors (physical fatigue, GI-specific anxiety, perceived stress, pain catastrophizing, and trait anxiety) were significantly associated with the severity of GI symptoms. An increasing number of these psychological alterations also led to a gradual increase in the overall severity of GI symptoms.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2021)
Article
Engineering, Biomedical
Chih-Yuan Chuang, Yi-Ting Lin, Chen-Chung Liu, Lue-En Lee, Hsin-Yang Chang, An-Sheng Liu, Shu-Hui Hung, Li-Chen Fu
Summary: This study proposes a multimodal assessment model that predicts the severity of schizophrenia symptoms based on linguistic, acoustic, and visual behavior. The model combines deep learning techniques and a multimodal fusion framework to achieve superior performance in assessment.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Article
Rehabilitation
Pentagiotissa Stefanatou, Evgenia Tsompanaki, Michalis Lavdas, Eleni Giannouli, Irene Ralli, Stamatina Kalogerakou, Eleni Anyfandi, Stelios Stylianidis, Nikos Stefanis, Venetsanos Mavreas, George Konstantakopoulos
Summary: This study provides evidence that patient-rated needs, especially unmet needs, are strongly associated with perceived psychosocial disability and subjective quality of life of schizophrenia patients beyond symptom severity. Identifying and addressing patient-reported needs could facilitate psychosocial disability and subjective quality of life improvement more effectively than interventions focused solely on symptom remission.
DISABILITY AND REHABILITATION
(2023)
Article
Hematology
Donald L. Patrick, Annette Powers, Monika Parisi Jun, Yeonhee Kim, Jacob Garcia, Christine Dehner, David G. Maloney
Summary: The study found that treatment with lisocabtagene maraleucel (liso-cel) could significantly improve the overall health status and quality of life of patients with relapsed/refractory LBCL, particularly showing clinically meaningful improvements in fatigue. For treatment responders, the improvement in global health status/quality of life was more significant.
Article
Nursing
Wen-Chi Shen, Ming-Mo Hou, Tai-Lin Huang, Cheng-Hsu Wang, Yen-Min Huang, Jen-Shi Chen, Mei-Ling Chen
Summary: This study investigated the effects of transdermal buprenorphine on quality of life and symptoms in cancer patients. It found that transdermal buprenorphine could significantly improve overall quality of life and reduce the severity of symptoms, including nausea/vomiting, pain, insomnia, and constipation.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Multidisciplinary Sciences
Simon B. Larsson, Gustaf Stukat von Feilitzen, Maria E. Andersson, Per Sikora, Magnus Lindh, Rickard Norden, Staffan Nilsson, Robert Sigstrom
Summary: This study aimed to compare the symptom severity and general health between individuals with PCR confirmed COVID-19 and PCR negative controls. Results showed that symptoms were prevalent in all groups, with the most severe symptoms in subacute phase participants. Loss of smell or taste was the most specific symptom for COVID-19. In PCR positive participants, female gender, older age, and acute illness severity had larger effects on health rating.
SCIENTIFIC REPORTS
(2022)
Article
Urology & Nephrology
Kendra E. Wulczyn, Sophia H. Zhao, Eugene P. Rhee, Sahir Kalim, Tariq Shafi
Summary: This study found an association between decline in kidney function and worsening of uremic symptom severity in patients with chronic kidney disease. However, the magnitude of these changes is small and of uncertain clinical significance.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Medicine, General & Internal
Monika Sadlonova, Jochen Senges, Jonas Nagel, Christopher Celano, Caroline Klasen-Max, Martin Borggrefe, Ibrahim Akin, Dierk Thomas, Christopher Jan Schwarzbach, Thomas Kleeman, Steffen Schneider, Matthias Hochadel, Tim Sueselbeck, Harald Schwacke, Angelika Alonso, Markus Haass, Karl-Heinz Ladwig, Christoph Herrmann-Lingen
Summary: In patients with atrial fibrillation (AF), factors such as female sex, preexisting coronary artery disease, cardiac anxiety, stress from noise, work-related stress, and sleep disturbance are associated with higher symptom severity. Preexisting coronary artery disease, diabetes mellitus, generalized anxiety, cardiac anxiety, financial stress, and sleep disturbance are associated with impaired health-related quality of life (HRQoL).
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Psychiatry
Jinliang Chen, Hongli Song, Shuchun Li, Ziwei Teng, Yuhan Su, Jindong Chen, Jing Huang
Summary: This study aimed to describe the sociodemographic characteristics, social support received, and quality of life of chronically homeless patients with schizophrenia in China. Results indicated that the homeless patients were more likely to live outside the city and be ethnic minorities compared with non-homeless patients. Although the married proportion was higher among homeless patients, they had a higher rate of being divorced or widowed.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Oncology
Shu-Fen Niu, Sue-Yueh Cheng, Chia-Hui Chin
Summary: The study indicates that patients who undergo laparoscopic-assisted colectomy have higher quality of life and lower symptom severity compared to those who receive conventional open colectomy, highlighting the benefits of laparoscopic surgery in colorectal cancer patients.
Article
Public, Environmental & Occupational Health
Taeho Greg Rhee, Richard A. Marottoli, Joan K. Monin
Summary: The diversity of social networks is positively associated with HRQOL and QALYs in older adults, while perceived quality of social support is not associated with HRQOL.
PREVENTIVE MEDICINE
(2021)
Article
Oncology
Brittany Bouvron, Lynda Mackin, Kord M. Kober, Steven M. Paul, Bruce A. Cooper, Yvette P. Conley, Marilyn J. Hammer, Fay Wright, Jon D. Levine, Christine Miaskowski
Summary: This study examined pain and morning fatigue profiles in oncology outpatients receiving chemotherapy and identified five distinct profiles. Patients with severe pain and high morning fatigue often experienced depression, sleep disturbance, and decreased quality of life.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Medicine, Research & Experimental
Durmaz Onur, Haluk Usta, Batuhan Ayik, Ekin Sonmez Gungor, Cemre Ozdemir
Summary: This study aimed to compare clinical symptom severity and quality of life among schizophrenia patients based on their attitudes towards pandemic measures and reported lockdown-related disruption. The results showed that there were no significant differences in sociodemographic and clinical variables, clinical symptom severity, or quality of life between schizophrenia patients with positive attitudes and those without positive attitudes towards pandemic measures. However, guilt feelings and trait anxiety levels were positively related to lockdown-related disruption.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
(2023)
Article
Psychiatry
Siyuan Zheng, Ruoqi Wang, Shaofei Zhang, Yangxu Ou, Xuanlian Sheng, Meng Yang, Menglin Ge, Lei Xia, Jun Li, Xiaoqin Zhou
Summary: This study found a significant incidence of depressive symptoms associated with schizophrenia, with depression severity serving as a mediating variable connecting stigma and quality of life, partially moderating the association.
Article
Oncology
Xiangyu Liu, Yongyi Chen, Andy S. K. Cheng, Yingchun Zeng, Shahid Ullah, Michael Feuerstein
Summary: The study identified two major clusters of problems experienced by breast cancer survivors: functional limitations and multi-problems. Those falling into the multi-problem cluster had poorer quality of life.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Review
Health Care Sciences & Services
Ruishuang Zheng, Qiaohong Guo, Zhiqian Chen, Yingchun Zeng
Summary: The study found that dignity therapy did not improve the sense of dignity, hope, spiritual well-being, and quality of life of terminally ill patients. However, it was effective in reducing anxiety and depression, both immediately after the intervention and at 4 weeks post-intervention.
BMJ SUPPORTIVE & PALLIATIVE CARE
(2023)
Article
Nursing
Wenmin Hou, Qiaoping Li, Xiangyu Liu, Yingchun Zeng, Andy S. K. Cheng
Summary: This study aimed to investigate the factors affecting the return to work for breast cancer patients. Findings revealed that factors such as cognitive symptoms, depression, fatigue, and work ability significantly influenced employment readiness. Higher skill levels, better social support, and flexible work schedules were found to facilitate the return to work process, while stress, lack of confidence, depression, and fatigue were identified as barriers.
INTERNATIONAL JOURNAL OF NURSING SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Yue Su, Huiru Lu, Qi Li, Zhouchuan Shao, Shuxiang Wang, Yue Quan, Yingchun Zeng, Yaxin Zheng
Summary: The study investigated the stability of co-assembling nanoaggregates using a fluorescence resonance energy transfer method, finding that only by simultaneously increasing the hydrophobicity of both camptothecin and curcumin could stable co-assembling NAs be obtained. This highlights the importance of co-assembly and disassembly of NAs formed by various hydrophobic drugs for designing stable co-delivery systems resistant to blood dilution after intravenous injection.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2021)
Article
Pharmacology & Pharmacy
Chun-Mei Long, Qi-Xue Zheng, Yi Zhou, Yuan-Ting Liu, Liu-Ping Gong, Ying-Chun Zeng, Sha Liu
Summary: Research shows that NITyr has protective effects on neurons, improves behavior and memory in Alzheimer's disease model mice, with its mechanism mainly mediated by inducing autophagy, primarily through the CB2 receptor.
JOURNAL OF PHARMACOLOGICAL SCIENCES
(2021)
Review
Psychology, Clinical
Andy S. K. Cheng, Xiaoming Wang, Niu Niu, Minyu Liang, Yingchun Zeng
Summary: The aim of this network meta-analysis was to evaluate the comparative effects of neuropsychological interventions for cancer-related cognitive impairment (CRCI) and rank the best intervention options for adult cancer patients. The study found that cognitive behavioral therapies, cognitive rehabilitation, and cognitive training showed statistically significant differences in managing subjective cognition. Meditation or mindfulness-based interventions were the most effective for attention, while cognitive training had the best results for verbal memory and processing speed. Psychoeducation was most effective for executive function, and cognitive training was the best option for verbal fluency. The importance of this study lies in its findings for the management of CRCI in cancer patients.
NEUROPSYCHOLOGY REVIEW
(2022)
Review
Management
Junhong Zhu, Kaiyuan Shi, Chengyue Yang, Yanping Niu, Yingchun Zeng, Ning Zhang, Tao Liu, Charlene H. Chu
Summary: The current research on the ethics of smart home technologies for elderly care focuses on issues such as privacy, autonomy, safety guarantee, and reduced human contact. Establishing an ethical framework is essential for the sustainable development of smart, home-based elderly care. Nurses can play a crucial role in promoting ethical awareness and practice in the design and implementation of these technologies.
JOURNAL OF NURSING MANAGEMENT
(2022)
Article
Nursing
Yingchun Zeng, Linghui Zeng, Andy S. K. Cheng, Xijun Wei, Boran Wang, Jingchi Jiang, Jin Zhou
Summary: This study explored the potential effects of VR-assisted cognitive rehabilitation intervention for patients with cancer. The results showed significant improvements in cognitive function and sleep disorders. Further research is needed to validate these findings and increase the sample size.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Nursing
Yingchun Zeng, Linghui Zeng, Chong Zhang, Andy S. K. Cheng
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Nursing
Guolong Zhang, Huiwen Weng, Yinghong Li, Pingdong Li, Yucui Gong, Jieya Chen, Lin Wei, Linghui Zeng, Yingchun Zeng, Andy SK. Cheng
Summary: This study aimed to examine symptom severity and interference in lung cancer patients treated with PD-1 immunotherapy, explore the clustering of symptoms, and identify factors associated with symptom clusters. The results showed that the overall symptom burden of these patients was mild, and symptom clusters were identified. Each symptom in a cluster should be treated simultaneously or in an orderly manner.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Nursing
Xiumei Wu, Qiongyao Guan, Andy S. K. Cheng, Changhe Guan, Yan Su, Jingchi Jiang, Boran Wang, Linghui Zeng, Yingchun Zeng
Summary: This study aimed to develop and validate classification models using machine learning algorithms to predict breast cancer-related lymphedema (BCRL) in Chinese women. The logistic regression model achieved the best performance, and the most important predictors were the number of positive lymph nodes, BCRL occurring on the same side as the surgery, a history of sentinel lymph node biopsy, a dietary preference for meat and fried food, and an exercise frequency of less than three times per week.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Editorial Material
Nursing
Qiaohong Guo, Yingchun Zeng
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2022)
Article
Nursing
Yingchun Zeng, Qiongyao Guan, Yan Su, Qiubo Huang, Jun Zhao, Minghui Wu, Qiaohong Guo, Qiyuan Lyu, Yiyu Zhuang, Andy S. K. Cheng
Summary: This study aimed to explore the feasibility and validity of a self-administered immersive virtual reality (VR) tool for assessing cognitive impairment in cancer patients. The immersive tool was used to assess attention, verbal learning memory, processing speed, executive function, and verbal fluency through an interactive VR scenario. The results showed a moderate to strong positive correlation between the VR cognition assessment and paper-and-pencil neurocognitive tests, indicating high concurrent validity. The VR-based cognition assessment tool demonstrated feasibility and acceptability for measuring cognitive impairment in cancer patients.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2023)
Article
Nursing
Hongxia Xie, Niu Niu, Zhaoyan Ming, Minghui Wu, Linghui Zeng, Yingchun Zeng
Summary: This study provides an overview of the current state of research on cancer-related cognitive impairment (CRCI) and identifies research opportunities for future studies. The study analyzed published articles from different databases and found that the United States, China, and Canada were the top contributors. The study also identified breast cancer and brain tumors as the dominant cancer types and highlighted the importance of treatment and adverse effects in CRCI research.
ASIA-PACIFIC JOURNAL OF ONCOLOGY NURSING
(2023)
Article
Public, Environmental & Occupational Health
Ying Cui, Yanhua Deng, Borong Zhou, Yingchun Zeng, Andy S. K. Cheng
Summary: This study found that the prevalence of postnatal depression among new Chinese fathers in Guangzhou was 24.1%. Depressive symptoms were significantly associated with employment status and vulnerable personality traits. Factors such as higher family income, planned pregnancy, having a child of the desired gender, more family support, and objective support were identified as protective factors.
JOURNAL OF MENS HEALTH
(2021)
