Article
Medicine, General & Internal
Janine Wirkner, Matthias Scheuch, Thomas Dabers, Sabrina Freiin von Rheinbaben, Beate Fiene, Simone Aymanns, Karlhans Endlich, Nicole Endlich, Uwe Lendeckel, Rainer Rettig, Hans Joergen Grabe, Sylvia Stracke
Summary: This study examined various factors influencing health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients, with a focus on the impact of dialysis, depression, and diabetes. The results highlighted the importance of recognizing and treating depression to improve HRQOL and potentially enhance patient outcomes and reduce hospitalization rates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Manon J. M. van Oosten, Dan Koning, Susan J. J. Logtenberg, Martijn J. H. Leegte, Henk J. G. Bilo, Marc H. Hemmelder, Kitty J. Jager, Vianda S. Stel
Summary: This study investigated the prevalence of chronic antidepressant use among chronic kidney disease patients in the Netherlands. It found that the prevalence of chronic antidepressant prescription was significantly higher in CKD patients with and without kidney replacement therapy compared to controls. The use of antidepressant medication was more common in female patients and those aged 45-64 years, but not associated with socio-economic status.
CLINICAL KIDNEY JOURNAL
(2022)
Article
Urology & Nephrology
Kendra E. Wulczyn, Sophia H. Zhao, Eugene P. Rhee, Sahir Kalim, Tariq Shafi
Summary: This study found an association between decline in kidney function and worsening of uremic symptom severity in patients with chronic kidney disease. However, the magnitude of these changes is small and of uncertain clinical significance.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Review
Urology & Nephrology
Rajiv Agarwal, James Burton, Maurizio Gallieni, Kamyar Kalantar-Zadeh, Gert Mayer, Carol Pollock, Jacek C. Szepietowski
Summary: Despite the limited increase in life expectancy for patients with end-stage kidney disease after the breakthrough of kidney replacement therapy, the quality of life and relief of symptoms have become increasingly important to patients. Currently, most dialysis-associated symptoms and adverse effects do not have approved treatments, and the few available treatments may add further adverse effects. This article demonstrates how understanding the pathophysiology of a particular symptom (chronic kidney disease-associated pruritus) in dialysis led to the development and regulatory approval of a treatment for that symptom. This approach can be applied to other dialysis-associated symptoms, improving the remaining years of patients' lives.
CLINICAL KIDNEY JOURNAL
(2023)
Review
Nutrition & Dietetics
Carlo Garofalo, Chiara Ruotolo, Claudia Annoiato, Maria Elena Liberti, Roberto Minutolo, Luca De Nicola, Giuseppe Conte, Silvio Borrelli
Summary: A systematic review and meta-analysis revealed that approximately 1.5% of patients undergoing maintenance dialysis experience recovery of kidney function unrelated to acute kidney injury. The prevalence of recovery is higher in the United States compared to other countries.
Article
Urology & Nephrology
Esther N. M. de Rooij, Yvette Meuleman, Johan W. de Fijter, Saskia Le Cessie, Kitty J. Jager, Nicholas C. Chesnaye, Marie Evans, Agneta A. Pagels, Fergus J. Caskey, Claudia Torino, Gaetana Porto, Maciej Szymczak, Christiane Drechsler, Christoph Wanner, Friedo W. Dekker, Ellen K. Hoogeveen
Summary: This study investigated the changes in health-related quality of life before and after the initiation of dialysis in older patients with kidney failure. The results showed a significant decline in both mental and physical health-related quality of life in the year preceding dialysis, which stabilized in the year following dialysis.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Review
Nutrition & Dietetics
Aleksandra Beata Juszczak, Maciej Kupczak, Tomasz Konecki
Summary: This narrative review summarizes 98 studies of chronic kidney disease (CKD) and the effects of vitamin supplementation on patients on dialysis. The findings suggest potential effectiveness of certain vitamins, such as B, D, or C, but recommendations for vitamins A and K are still unclear due to potential toxicity. Further research is needed to evaluate the effectiveness and risks of vitamin supplementation for CKD patients.
Article
Endocrinology & Metabolism
Joao Victor Salgado, Miguel Angelo Goes, Natalino Salgado Filho
Summary: The global nephrology community acknowledges the increasing burden of kidney disease and emphasizes on early diagnosis, understanding of disease progression, and development of new therapeutic interventions. FGF21 is considered a key regulator of lipid, glucose, and energy metabolism, as well as stress responses. While promising results have been shown with FGF21 analogs in metabolic disease, its exact role in kidney function remains poorly understood.
METABOLISM-CLINICAL AND EXPERIMENTAL
(2021)
Article
Nursing
Harith Eranga Yapa, Louise Purtell, Shirley Chambers, Ann Bonner
Summary: This study aimed to compare symptoms and health-related quality of life in chronic kidney disease patients and found that as kidney function deteriorated, symptoms worsened and health-related quality of life decreased. Early identification and proactive management by nurses are crucial for reducing symptom burden and improving quality of life in these patients.
JOURNAL OF CLINICAL NURSING
(2021)
Article
Medicine, General & Internal
Lin Wang, Ming-Hui Xin, Yan Ma, Yu Wang, Meng-Yuan Hu, Qiang-Qiang Liu, Jin-Bor Chen
Summary: By comparing the quality of life (QoL) scores before and after parathyroidectomy (PTX), it was found that PTX can improve the QoL of dialysis patients with medically refractory secondary hyperparathyroidism. After PTX, nutritional markers improved and several domain scale scores of KDQOL-36, including Symptoms and Problems of Kidney Disease, Burden of Kidney Disease, Effects of Kidney Disease, Physical Component Summary (PCS) score, and Mental Component Summary score, significantly increased. Furthermore, the duration of PTX was found to have a significant negative correlation with PCS subscale scores and a positive correlation with EKD subscale scores.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2022)
Article
Medicine, General & Internal
Ganesh Sritheran Paneerselvam, Khang Wen Goh, Yaman Walid Kassab, Muhammad Junaid Farrukh, Bey Hing Goh, Pei Lin Lua, Andi Hermansyah, Long Chiau Ming
Summary: This study assessed the quality of life of dialysis patients and examined its determinants. The results showed no significant difference in the mean score of health-related quality of life components among different dialysis types. Demographic data did not significantly affect the quality of life of dialysis patients. Patients with a dialysis duration of more than 5 years had a better quality of life. Laboratory parameters such as low albumin and low hemoglobin showed a significant correlation with the health-related quality of life of dialysis patients.
FRONTIERS IN MEDICINE
(2023)
Article
Nursing
Hayfa Almutary
Summary: This study examined the association between depression, excessive daytime sleepiness (EDS), and quality of life (QOL) in patients undergoing dialysis. The results showed that depression and EDS were highly prevalent among these patients, with depression being the main predictor of QOL. Therefore, screening for these unpleasant symptoms should be included in standard clinical practice.
APPLIED NURSING RESEARCH
(2022)
Article
Medicine, General & Internal
Michela Musolino, Pierangela Presta, Paola Cianfrone, Maria Antonietta Errante, Michele Andreucci, Giuseppe Coppolino, Davide Bolignano
Summary: This study explored the relationship between the level of physical activity and severity of mood disturbances in patients with end-stage kidney disease. The results showed that physical inactivity and mood disturbances were significantly inter-connected in these patients and could impact their quality of life, autonomic dysfunction, and long-term outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Hanna Cholerzynska, Wiktoria Zasada, Hanna Michalak, Milosz Miedziaszczyk, Andrzej Oko, Ilona Idasiak-Piechocka
Summary: Acute kidney injury (AKI) and sudden exacerbation of chronic kidney disease (CKD) often require urgent kidney replacement therapy (UKRT). Peritoneal dialysis (PD) is seen as a viable option for managing these patients. This review examines recent literature on the clinical outcomes of urgent-start peritoneal dialysis (USPD) in CKD and AKI.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Natalia Dryjanska, Katarzyna Kilis-Pstrusinska
Summary: Depression is a significant health problem, especially among children and adolescents, and it is more prevalent in patients with chronic diseases such as chronic kidney disease (CKD). This review discusses the high risk of developing depression in adolescents and females, and the impact of depression on the quality of life of children and adolescents with CKD. The stage of the disease, age of CKD diagnosis, and type of treatment significantly affect the health-related quality of life (HRQoL) and caregiver burden. Screening for depression is recommended for CKD patients, and transdiagnostic tools should be used for symptom alleviation. Preventative strategies should be considered for children at risk of developing depression.
JOURNAL OF CLINICAL MEDICINE
(2023)
