Journal
KIDNEY INTERNATIONAL
Volume 74, Issue 5, Pages 553-555Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/ki.2008.323
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The paper by Sharyo et al. shows that statins reduce the severity in a model of renal-ischemia reperfusion injury and raises the therapeutic possibility of using statins as pharmacological intervention against acute kidney injury. This, together with previous studies, indicates that statins exert a wide spectrum of anti-inflammatory, immunomodulatory, and protective effects besides their lipid-lowering function.
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