Journal
PSYCHIATRIA POLSKA
Volume 49, Issue 2, Pages 225-241Publisher
WYDAWNICZY POLSKIEGO TOWARZYSTWA
DOI: 10.12740/PP/39370
Keywords
schizophrenia; long-acting antipsychotics; arpiprazole; olanzapine; paliperidone; risperidone; guidelines for use
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Long-acting injectable antipsychotics constitute a valuable alternative for the treatment of psychotic disorders, mainly schizophrenia. They assure a more stable drug level, improve treatment compliance, and increase the chances for favorable and long-lasting improvement. Additionally, the long-acting second-generation antipsychotics combine the values of long-acting injectable drugs with the values of atypical antipsychotics. Four second generation long-acting antipsychotics have been described: risperidone, olanzapine, aripiprazole and paliperidone. The indications for their use, treatment strategy, tolerance, and potential interactions are discussed.
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