Inhibition of Delta-6 Desaturase Reverses Cardiolipin Remodeling and Prevents Contractile Dysfunction in the Aged Mouse Heart Without Altering Mitochondrial Respiratory Function

Cardiac Aging: From Molecular Mechanisms to Significance in Human Health and Disease

(2012) Dao-Fu Dai et al.   ANTIOXIDANTS & REDOX SIGNALING

Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart

(2012) Christopher M. Mulligan et al.   CARDIOVASCULAR RESEARCH

Dietary Docosahexaenoic Acid (22:6) Incorporates into Cardiolipin at the Expense of Linoleic Acid (18:2): Analysis and Potential Implications

(2012) Colin Cortie et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Function in Permeabilized Cardiomyocytes Is Largely Preserved in the Senescent Rat Myocardium

(2012) Martin Picard et al.   PLoS One

The complexity of cardiolipin in health and disease

(2011) Steven M. Claypool et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondria and the aging heart

(2011) Chaudhary Ketul R et al.   Journal of Geriatric Cardiology

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

(2010) Martin Picard et al.   AGING CELL

Cardiolipin Remodeling by ALCAT1 Links Oxidative Stress and Mitochondrial Dysfunction to Obesity

(2010) Jia Li et al.   Cell Metabolism

Cardiac Aging in Mice and Humans: The Role of Mitochondrial Oxidative Stress

(2010) Dao-Fu Dai et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Formation of molecular species of mitochondrial cardiolipin. 1. A novel transacylation mechanism to shuttle fatty acids between sn-1 and sn-2 positions of multiple phospholipid species

(2009) Ashim Malhotra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Cyclooxygenase and thromboxane/prostaglandin receptor contribute to aortic endothelium-dependent dysfunction in aging female spontaneously hypertensive rats

(2009) Drew A. Graham et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cardiac 12/15 lipoxygenase–induced inflammation is involved in heart failure

(2009) Yosuke Kayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Eicosanoid signalling pathways in the heart

(2008) C. M. Jenkins et al.   CARDIOVASCULAR RESEARCH

Age-related alterations in oxidatively damaged proteins of mouse heart mitochondrial electron transport chain complexes

(2008) Kashyap B. Choksi et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acyl-CoA:Lysophospholipid Acyltransferases

(2008) Hideo Shindou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rat heart cannot synthesize docosahexaenoic acid from circulating α-linolenic acid because it lacks elongase-2

(2008) Miki Igarashi et al.   JOURNAL OF LIPID RESEARCH