Article
Biodiversity Conservation
Anuja Sharma, Shilpa Sharma, Shilippreet Kour, Achhada Ujalkaur Avatsingh, Kahkashan Perveen, Jamilah A. Alsulami, Nasib Singh
Summary: The prevalence of gastrointestinal parasites in small and large ruminants in northern India's agro-climatic region is high, especially during the rainy season. The study emphasizes the need for preventive and control strategies for effective animal health management.
Article
Multidisciplinary Sciences
Xinlei Yan, Wenying Han, Xindong Jin, Yufei Sun, Jialu Gao, Xiuli Yu, Jun Guo
Summary: The study found that koumiss has a certain effect on preventing and treating Toxoplasma gondii infection. Koumiss treatment can reduce the number of brain cysts and increase the abundance of certain bacteria associated with preventing T. gondii infection. Moreover, koumiss can inhibit or ameliorate T. gondii infection by regulating unique metabolic pathways.
SCIENTIFIC REPORTS
(2022)
Article
Microbiology
Jonah Kupritz, Angelina Angelova, Thomas B. Nutman, Pedro H. Gazzinelli-Guimaraes
Summary: A comprehensive qualitative review and quantitative meta-analysis of 23 studies revealed that helminth infections dynamically shift the intestinal microbiome structure, with specific effects seen in soil-transmitted helminth species on the microbiome composition.
Article
Gastroenterology & Hepatology
Manasi Agrawal, Kristine H. H. Allin, Aske T. T. Iversen, Saurabh Mehandru, Jean-Frederic Colombel, Tine Jess
Summary: According to this study, early-life exposure to mebendazole is associated with increased risk of adult-onset UC, but not Crohn's disease. This suggests the importance of early-life exposures in shaping the risk of IBD later in life.
AMERICAN JOURNAL OF GASTROENTEROLOGY
(2022)
Article
Zoology
Aline Aguiar, Drausio Honorio Morais, Lidiane A. Firmino Silva, Luciano Alves Dos Anjos, Ottilie Carolina Foster, Reinaldo Jose Da Silva
Summary: The study presents the richness of metazoan endoparasites associated with 25 anuran species in a transitional area between Cerrado and Atlantic Rain Forest from Brazil, detailing the types, quantities, prevalence, and distribution among host populations of these parasites.
Review
Chemistry, Medicinal
Cal Koger-Pease, Dilhan J. J. Perera, Momar Ndao
Summary: Despite the devastating impact and widespread occurrence of parasitic diseases globally, vaccines against parasites have been slower to develop compared to vaccines against viral and bacterial infections. One of the main challenges is the lack of vaccine strategies that can induce the complex and multifaceted immune responses required to eliminate parasitic persistence. Adenovirus (AdV) vectors have emerged as a potential solution for complex diseases like parasitic infections by driving CD8+ T cell responses, which are known to be important in immunity against many parasitic organisms. This review discusses recent advances in AdV-vectored vaccines targeting five major human parasitic diseases: malaria, Chagas disease, schistosomiasis, leishmaniasis, and toxoplasmosis. The use of AdV-vectored vaccines shows promise in tackling the historically challenging goal of developing vaccines for parasitic diseases.
Article
Genetics & Heredity
Gabrielle M. Becker, Joan M. Burke, Ronald M. Lewis, James E. Miller, James L. M. Morgan, Benjamin D. Rosen, Curtis P. Van Tassell, David R. Notter, Brenda M. Murdoch
Summary: Gastrointestinal nematodes pose a severe threat to sheep production. Drug resistance and environmental concerns have led to the exploration of alternative control methods. This study identified genetic variants associated with resistance to nematode infection in Katahdin sheep, providing insights into the genetic mechanisms of host response to nematodes.
FRONTIERS IN GENETICS
(2022)
Article
Infectious Diseases
Katharina Stracke, Poom Adisakwattana, Suparat Phuanukoonnon, Tippayarat Yoonuan, Akkarin Poodeepiyasawat, Paron Dekumyoy, Kittipong Chaisiri, Alexandra Roth Schulze, Stephen Wilcox, Harin Karunajeewa, Rebecca J. Traub, Aaron R. Jex
Summary: Soil-transmitted helminth infections have a significant negative impact on global population health, especially affecting children disproportionately. The lack of infection prevalence data in many endemic regions highlights the importance of molecular tools for establishing accurate epidemiological profiles. The gut microbiota can be influenced by medication, lifestyle factors, and co-inhabitation with parasites, but baseline studies in this area are limited.
PLOS NEGLECTED TROPICAL DISEASES
(2021)
Article
Infectious Diseases
Shumaila Irum, Arbab Ahsan, Haroon Ahmed, Aisha Khan, Guan Yayi, Mudabbar Mehboob, Seyma Gunyakti Kilinc, Harun Kaya Kesik, Muhammad Sohail Afzal, Shahzad Ali, Majid Mehmood, Figen Celik, Sami Simsek
Summary: The study found that common intestinal parasites, including helminths and protozoa, were prevalent in stool samples of patients in the pathology ward of General Hospital in Gujranwala. Infections were predominantly caused by helminths, with A. lumbricoides being the most common parasite. Contaminated water, food, soil, and surrounding environment were significant factors influencing the prevalence of parasitic species.
JOURNAL OF INFECTION IN DEVELOPING COUNTRIES
(2021)
Article
Infectious Diseases
Jani J. Sormunen, Satu Makela, Tero Klemola, Theophilus Y. Alale, Eero J. Vesterinen
Summary: The molecular identification of blood meal sources in ticks has been studied for several decades, but no widely used method has been established. A recent study developed qPCR assays based on retrotransposons to detect blood meal fragments in North American host species. In this study, the assays were used to identify blood meal sources and screen for tick-borne pathogens in ticks collected from Finland. The results showed that voles, shrews, and red squirrels were the main blood meal sources for Ixodes ricinus larvae, with red squirrels having the highest probability of carrying Borrelia.
TICKS AND TICK-BORNE DISEASES
(2023)
Article
Biology
Wali Khan, Noor-un-Nisa, Naseem Rafiq, Zubia Masood, Munawar Salim Ahmed, Hafeez Ur Rahman, Muhammad Kabir, Rukhsana Ghaffar, Attiqa Naz, Muhammad Ishaq Ali Shah
Summary: The present study conducted in Swat district of Pakistan showed that black rats harbor 8 species of helminth parasites of zoonotic importance, with an infection rate of 23.7%. Adult rats were found to be more susceptible to parasitic infections compared to sub-adults.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2021)
Article
Environmental Sciences
Hafizah Hasan, Alison Parker, Simon J. T. Pollard
Summary: This study explores the interplay between preventative risk management and regulatory style for the implementation of water safety plans in Malaysia and in England and Wales. Interviews and focus group discussions revealed themes related to the transition from drinking water quality surveillance to preventative risk management, including compliance policy concerns, overseeing risk management controls, and the portfolio of interventions suited to a more facilitative regulatory style.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Parasitology
Altangerel T. Dursahinhan, Daniel R. Brooks, Sebastian Botero-Canola, Scott L. Gardner
Summary: This study reports the first helminth parasite species found in the mole-vole and describes a new species, Arostrilepis batsaikhani. The new species closely resembles Arostrilepis microtis but differs in genetic distance, size of cirrus spines, size of testes, and size of eggs.
Article
Parasitology
Kevin M. Santana-Hernandez, Jorge Oros, Simon L. Priestnall, Catalina Monzon-Arguello, Eligia Rodriguez-Ponce
Summary: The California kingsnake poses a significant threat to endemic species conservation in Gran Canaria, but its role in spreading potential invasive parasites is not proven. A parasitological study is urgently required to investigate the snake's parasitic fauna and potential zoonotic risks.
Review
Endocrinology & Metabolism
Claire Rennie, Ritin Fernandez, Sheila Donnelly, Kristine C. Y. McGrath
Summary: This systematic review and meta-analysis indicates that helminth infection may improve metabolic outcomes in human populations, with live infection with S. mansoni showing the most significant positive changes.
FRONTIERS IN ENDOCRINOLOGY
(2021)