Proteomics as an innovative tool to investigate frontotemporal disorders

The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease

(2015) Christina M. Lill et al.   Alzheimers & Dementia

Neuroproteomics tools in clinical practice

(2015) Ganna Shevchenko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Cerebrospinal fluid proteomics and protein biomarkers in frontotemporal lobar degeneration: Current status and future perspectives

(2015) Patrick Oeckl et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

TREM2 is associated with increased risk for Alzheimer’s disease in African Americans

(2015) Sheng Chih Jin et al.   Molecular Neurodegeneration

Retromer in Alzheimer disease, Parkinson disease and other neurological disorders

(2015) Scott A. Small et al.   NATURE REVIEWS NEUROSCIENCE

More evidence for association of a rare TREM2 mutation (R47H) with Alzheimer's disease risk

(2015) Samantha L. Rosenthal et al.   NEUROBIOLOGY OF AGING

Plasma levels of progranulin and interleukin-6 in frontotemporal lobar degeneration

(2015) Linda Gibbons et al.   NEUROBIOLOGY OF AGING

State of the art of 2D DIGE

(2015) Georgia Arentz et al.   Proteomics Clinical Applications

Salivary proteomics and biomarkers in neurology and psychiatry

(2015) Kelly L. Wormwood et al.   Proteomics Clinical Applications

Disease-Associated Mutations of TREM2 Alter the Processing of N-Linked Oligosaccharides in the Golgi Apparatus

(2015) Ji-Seon Park et al.   TRAFFIC

Progress in unraveling the genetic etiology of Parkinson disease in a genomic era

(2015) Aline Verstraeten et al.   TRENDS IN GENETICS

TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies

(2015) Joery Goossens et al.   Acta Neuropathologica Communications

Genetic Heterogeneity in Alzheimer Disease and Implications for Treatment Strategies

(2014) John M. Ringman et al.   Current Neurology and Neuroscience Reports

Imaging Frontotemporal Lobar Degeneration

(2014) Janine Diehl-Schmid et al.   Current Neurology and Neuroscience Reports

What is frontotemporal dementia?

(2014) Alexander Kurz et al.   MATURITAS

Homozygous TREM2 mutation in a family with atypical frontotemporal dementia

(2014) Isabelle Le Ber et al.   NEUROBIOLOGY OF AGING

Progranulin protein levels are differently regulated in plasma and CSF

(2014) A. M. Nicholson et al.   NEUROLOGY

Tale of two diseases: Amyotrophic lateral sclerosis and frontotemporal dementia

(2014) Ashok Verma   NEUROLOGY INDIA

Proteomic Analysis of Lymphoblastoid Cells from Nasu-Hakola Patients: A Step Forward in Our Understanding of This Neurodegenerative Disorder

(2014) Serena Giuliano et al.   PLoS One

TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis

(2014) G. Kleinberger et al.   Science Translational Medicine

Frontotemporal Lobar Degeneration: A Clinical Approach

(2014) Elissaios Karageorgiou et al.   SEMINARS IN NEUROLOGY

Systems Approach to Neurodegenerative Disease Biomarker Discovery

(2013) Christopher Lausted et al.   Annual Review of Pharmacology and Toxicology

Diagnosis and Management of Behavioral Variant Frontotemporal Dementia

(2013) Peter S. Pressman et al.   BIOLOGICAL PSYCHIATRY

TREM2 in neurodegeneration: evidence for association of the p.R47H variant with frontotemporal dementia and Parkinson’s disease

(2013) Sruti Rayaprolu et al.   Molecular Neurodegeneration

The genetics and neuropathology of frontotemporal lobar degeneration

(2012) Anne Sieben et al.   ACTA NEUROPATHOLOGICA

Fused in sarcoma (FUS) interacts with the cytolinker protein plectin: Implications for FUS subcellular localization and function

(2012) Christer Thomsen et al.   EXPERIMENTAL CELL RESEARCH

Quantitative Analysis of the Detergent-Insoluble Brain Proteome in Frontotemporal Lobar Degeneration Using SILAC Internal Standards

(2012) Nicholas T. Seyfried et al.   JOURNAL OF PROTEOME RESEARCH

Proteomic Analysis Identifies Dysfunction in Cellular Transport, Energy, and Protein Metabolism in Different Brain Regions of Atypical Frontotemporal Lobar Degeneration

(2012) Daniel Martins-de-Souza et al.   JOURNAL OF PROTEOME RESEARCH

Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice

(2012) Ajeet Rijal Upadhaya et al.   NEUROBIOLOGY OF AGING

Biological and methodical challenges of blood-based proteomics in the field of neurological research

(2012) Simone Lista et al.   PROGRESS IN NEUROBIOLOGY

Asparaginyl endopeptidase cleaves TDP-43 in brain

(2012) Jeremy H. Herskowitz et al.   PROTEOMICS

Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia

(2011) Katya Rascovsky et al.   BRAIN

Astrocytic neuroprotection through induction of cytoprotective molecules; a proteomic analysis of mutant P301S tau-transgenic mouse

(2011) Kenichiro Yata et al.   BRAIN RESEARCH

Frontotemporal Dementia: From Mendelian Genetics Towards Genome Wide Association Studies

(2011) Raffaele Ferrari et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration

(2011) Yair M Gozal et al.   Molecular Neurodegeneration

Proteomic Analysis of Hippocampal Dentate Granule Cells in Frontotemporal Lobar Degeneration: Application of Laser Capture Technology

(2011) Yair M. Gozal et al.   Frontiers in Neurology

Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration

(2010) Agnes L. Nishimura et al.   BRAIN

TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration

(2010) C. Lagier-Tourenne et al.   HUMAN MOLECULAR GENETICS

Optimization protocol for amyloid-β peptides detection in human cerebrospinal fluid using SELDI TOF MS

(2010) Valentina Albertini et al.   Proteomics Clinical Applications

The role of proteomics in dementia and Alzheimer’s disease

(2009) Maria Zellner et al.   ACTA NEUROPATHOLOGICA

Serum biomarker for progranulin-associated frontotemporal lobar degeneration

(2009) Kristel Sleegers et al.   ANNALS OF NEUROLOGY

Plasma progranulin levels predict progranulin mutation status in frontotemporal dementia patients and asymptomatic family members

(2009) N. Finch et al.   BRAIN

Proteomics Analysis Reveals Novel Components in the Detergent-Insoluble Subproteome in Alzheimer’s Disease

(2009) Yair M. Gozal et al.   JOURNAL OF PROTEOME RESEARCH

Proteomics of Human Neurodegenerative Diseases

(2008) Jing Zhang et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Biomarker discovery in neurodegenerative diseases: A proteomic approach

(2008) Min Shi et al.   NEUROBIOLOGY OF DISEASE

Low plasma progranulin levels predict progranulin mutations in frontotemporal lobar degeneration

(2008) R. Ghidoni et al.   NEUROLOGY

Stable isotopic labeling in proteomics

(2008) Kris Gevaert et al.   PROTEOMICS

CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction

(2008) Mirko Bibl et al.   Proteomics Clinical Applications