Article
Materials Science, Multidisciplinary
Yanbo Wu, Li Tang, Qiang Zhang, Fansheng Kong, Yongguang Bi
Summary: Nanoscale bioactive glasses were successfully synthesized with remarkable mono-dispersity and uniform spherical morphology using a surfactant-free microemulsion strategy combined with ultrasound irradiation. The bioactive glass nanoparticles demonstrated excellent apatite-forming activity, making them a promising candidate for local sustained delivery in bone tissue engineering.
Article
Polymer Science
Lei Li, Pengfei Lu, Yuting Liu, Junhe Yang, Shengjuan Li
Summary: In this study, 3D bioactive glass/lignocellulose composite scaffolds were successfully fabricated by 3D-printing with NMMO as the ink solvent. The scaffolds showed uniform macropores and rough surfaces, with excellent mechanical properties and hydroxyapatite-forming capability. They also exhibited low cytotoxicity to human bone marrow mesenchymal stem cells. These 3D-printed BG/cellulose scaffolds have potential applications in bone tissue engineering.
Article
Materials Science, Ceramics
Andrada Ioana Damian-Buda, Georgeta Voicu, Bogdan Stefan Vasile, Adela Banciu, Florin Iordache, Lucian Toma Ciocan
Summary: In this study, mesoporous bioactive glass nanoparticles (MBGNs) were successfully synthesized using a microemulsion assisted sol-gel method, showing good bioactivity and biocompatibility in vitro. Samples containing MgO increased cell viability, while MBGNs with ZnO exhibited higher antibacterial activity against Escherichia coli.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2021)
Article
Biochemistry & Molecular Biology
Mostafa Mabrouk, Hanan H. Beherei, Yukiko Tanaka, Masaru Tanaka
Summary: This study investigated the effect of titanium doping on the properties of bioactive glasses and their impact on cell death mode. The results showed that titanium doping had minimal influence on the thermal, physicochemical, and morphological properties of the bioactive glasses, but did affect the morphology, size, and charges of the BGT nano-powders. The presence of titanium enhanced the intermediate water content in hydrated BGTs and influenced the mode of cell death in osteosarcoma cell line exposed to the glasses.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Biotechnology & Applied Microbiology
Xiao Han, Yan Chen, Qian Jiang, Xin Liu, Yaming Chen
Summary: A novel bioactive glass (BAG)-modified hybrid composite resin has been developed, showing excellent mechanical properties, good biocompatibility, antibacterial and remineralizing capabilities. The balance between mechanical properties, toxicity, antibacterial activity, and bioactivity makes it a promising prospect for clinical application. The release of bioactive ions (Ca2+, Si4+) plays a key role in antibacterial and remineralizing activity.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2021)
Article
Biophysics
Jiansheng Lin, Ting Song, Zonghua Liu, Deguang Yang, Rong Xiang, Wenxi Hua, Huaibin Wan
Summary: This study thoroughly investigated the blood safety of MnO2 nanoparticles and found that their toxicity effects on red blood cells, platelets, coagulation functions, and key organs were concentration-dependent. These results provide important guidance for the clinical applications of MnO2 nanoparticles.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Polymer Science
Eirini A. Nakiou, Maria Lazaridou, Georgia K. Pouroutzidou, Anna Michopoulou, Ioannis Tsamesidis, Liliana Liverani, Marcela Arango-Ospina, Anastasia Beketova, Aldo R. Boccaccini, Eleana Kontonasaki, Dimitrios N. Bikiaris
Summary: This study explores a novel biopolyester poly(glycerol succinate) (PGSuc) reinforced with mesoporous bioactive nanoparticles (MSNs) as a new coating material for bone tissue engineering. The results show that polymer coatings with and without MSNs improved the physicochemical properties of the bioactive glass scaffolds and increased ALP activity and alizarin red staining, indicating osteogenic differentiation potential when cultured with adipose-derived mesenchymal stem cells.
Article
Materials Science, Ceramics
Narges Nasehi Gogajeh, Jafar Javadpour, Bijan Eftekhari Yekta
Summary: Bioactive glass microspheres (BGMs) were successfully produced using the sol-microemulsion-gel method, resulting in uniform and well-rounded microspheres under optimized conditions. Varying the reaction chamber size and stirring rate affected the diameter distribution of the microspheres, with increased stirring rate leading to the generation of smaller microspheres.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Multidisciplinary
Jiaxi Liu, Xiang Zhou, Yin Zhang, Wei Zhu, Anping Wang, Meijia Xu, Shuxian Zhuang
Summary: In this study, a composite hemostatic sponge composed of cerium-containing mesoporous bioactive glass and chitosan was prepared and compared with a commercially available gelatin sponge. The results showed that the composite sponge had superior hemostatic performance and validated its thrombosis, platelet adhesion, and blood compatibility. Additionally, the composite sponge exhibited strong antibacterial effects against common bacteria.
MATERIALS TODAY CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Kazumasa Murata, Ayako Washio, Takahiko Morotomi, Thira Rojasawasthien, Shoichiro Kokabu, Chiaki Kitamura
Summary: A novel bioactive glass based powder for retrograde filling material was developed, showing good physicochemical properties and biocompatibility. The material exhibited no adverse effects on cells and reduced inflammatory responses.
Article
Materials Science, Ceramics
Marcelo da Silva Mantini Viana, Thalita Marcolan Valverde, Breno Rocha Barrioni, Alfredo Miranda de Goes, Marcos Augusto de Sa, Marivalda de Magalhaes Pereira
Summary: This study obtained cobalt-containing nanoparticles with the potential to release pro-angiogenic ions using a sol-gel based method, which can be applied for tissue repair and tissue engineering.
CERAMICS INTERNATIONAL
(2022)
Article
Materials Science, Ceramics
Negar Azizabadi, Parviz Aberoomand Azar, Mohammad Saber Tehrani, Pirouz Derakhshi
Summary: In this study, bioactive glass with zinc and silver content was synthesized via the sol-gel route. The results showed that the samples with higher zinc and silver content exhibited better bioactivity, antibacterial properties, and formation of hydroxyapatite. Among all the specimens, the sample BG-A2Z3 demonstrated optimal properties and is considered the most suitable candidate for orthopedic applications.
JOURNAL OF NON-CRYSTALLINE SOLIDS
(2021)
Article
Materials Science, Multidisciplinary
Saeed Hesaraki, Mohammad Nouri-Felekori, Nader Nezafati, Shokoufeh Borhan
Summary: In this study, composite scaffolds containing tragacanth gum and bioactive glass nanoparticles were successfully fabricated, showing promising characteristics for bone tissue engineering applications. Morphological observations and characterization analysis confirmed the impact of BGNPs on scaffold structure and degradation rate.
MATERIALS TODAY COMMUNICATIONS
(2021)
Article
Materials Science, Ceramics
Shreyasi Majumdar, Sumit Kumar Hira, Himanshu Tripathi, Arepalli Sampath Kumar, Partha Pratim Manna, S. P. Singh, Sairam Krishnamurthy
Summary: The study demonstrates that barium doped bioactive glass has excellent biocompatibility and regenerative properties, as well as anti-inflammatory characteristics. This novel biomaterial can be used for therapeutic purposes under inflammatory conditions.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Multidisciplinary
Martin Kapp, Chunde Li, Zeqian Xu, Aldo R. Boccaccini, Kai Zheng
Summary: Bioactive glass nanoparticles (BGNs) were successfully synthesized with controllable Ca content, showing that the Ca did not significantly affect particle size and structure. The study revealed that the Ca content in BGNs is related to their protein adsorption behavior, with an initial increase in protein adsorption over time but a subsequent reduction with further incubation, especially in BGNs with higher Ca content.
