Nonspecific yet decisive: Ubiquitination can affect the native-state dynamics of the modified protein

Intrinsically disordered proteins in cellular signalling and regulation

(2015) Peter E. Wright et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterizing Substrate Selectivity of Ubiquitin C-Terminal Hydrolase-L3 Using Engineered α-Linked Ubiquitin Substrates

(2014) Mario F. Navarro et al.   BIOCHEMISTRY

The C-Terminal Domain of the Utrophin Tandem Calponin-Homology Domain Appears To Be Thermodynamically and Kinetically More Stable Than the Full-Length Protein

(2014) Swati Bandi et al.   BIOCHEMISTRY

Protein Unfolding by Biological Unfoldases: Insights from Modeling

(2014) Michał Wojciechowski et al.   BIOPHYSICAL JOURNAL

Disordered Proteinaceous Machines

(2014) Monika Fuxreiter et al.   CHEMICAL REVIEWS

Paradigms of protein degradation by the proteasome

(2014) Tomonao Inobe et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Systematic Exploration of Ubiquitin Sequence, E1 Activation Efficiency, and Experimental Fitness in Yeast

(2014) Benjamin P. Roscoe et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonenzymatic Polyubiquitination of Expressed Proteins

(2014) Hosahalli P. Hemantha et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Criteria for Selecting PEGylation Sites on Proteins for Higher Thermodynamic and Proteolytic Stability

(2014) Paul B. Lawrence et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Folding pathway of a multidomain protein depends on its topology of domain connectivity

(2014) Takashi Inanami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrinsically Disordered Segments Affect Protein Half-Life in the Cell and during Evolution

(2014) Robin van der Lee et al.   Cell Reports

PolyUbiquitin Chain Linkage Topology Selects the Functions from the Underlying Binding Landscape

(2014) Yong Wang et al.   PLoS Computational Biology

In the Multi-domain Protein Adenylate Kinase, Domain Insertion Facilitates Cooperative Folding while Accommodating Function at Domain Interfaces

(2014) V. V. Hemanth Giri Rao et al.   PLoS Computational Biology

The Challenge of Producing Ubiquitinated Proteins for Structural Studies

(2014) Serena Faggiano et al.   Cells

The complexity of recognition of ubiquitinated substrates by the 26S proteasome

(2013) Aaron Ciechanover et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Chemical strategies to understand the language of ubiquitin signaling

(2013) Caroline E. Weller et al.   BIOPOLYMERS

Multisteric Regulation by Structural Disorder in Modular Signaling Proteins: An Extension of the Concept of Allostery

(2013) Peter Tompa   CHEMICAL REVIEWS

Principles of Cotranslational Ubiquitination and Quality Control at the Ribosome

(2013) Stefanie Duttler et al.   MOLECULAR CELL

Evolution and functional cross-talk of protein post-translational modifications

(2013) Pedro Beltrao et al.   Molecular Systems Biology

Structural Propensities of Human Ubiquitination Sites: Accessibility, Centrality and Local Conformation

(2013) Yuan Zhou et al.   PLoS One

Synthetic polyubiquitinated  -Synuclein reveals important insights into the roles of the ubiquitin chain in regulating its pathophysiology

(2013) M. Haj-Yahya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of a protein conferred by an increase in folded state entropy

(2013) S. Dagan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding of multidomain proteins: Biophysical consequences of tethering even in apparently independent folding

(2013) Oshrit Arviv et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Enzymatic production of mono-ubiquitinated proteins for structural studies: The example of the Josephin domain of ataxin-3

(2013) Serena Faggiano et al.   FEBS Open Bio

Chemistry and Biology of the Ubiquitin Signal

(2012) Liat Spasser et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions

(2012) Koraljka Husnjak et al.   Annual Review of Biochemistry

The Ubiquitin System, an Immense Realm

(2012) Alexander Varshavsky   Annual Review of Biochemistry

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Structure of monoubiquitinated PCNA

(2012) Zhongtao Zhang et al.   CELL CYCLE

Intrinsic Flexibility of Ubiquitin on Proliferating Cell Nuclear Antigen (PCNA) in Translesion Synthesis

(2012) Richard G. Hibbert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multidomain Protein Solves the Folding Problem by Multifunnel Combined Landscape: Theoretical Investigation of a Y-Family DNA Polymerase

(2012) Yong Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The origins and evolution of ubiquitination sites

(2012) Tzachi Hagai et al.   Molecular BioSystems

The Size of the Proteasomal Substrate Determines Whether Its Degradation Will Be Mediated by Mono- or Polyubiquitylation

(2012) Nitzan Shabek et al.   MOLECULAR CELL

Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein function

(2012) Rachael Baker et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Intrinsic Disorder in Ubiquitination Substrates

(2011) Tzachi Hagai et al.   JOURNAL OF MOLECULAR BIOLOGY

Nonenzymatic Assembly of Natural Polyubiquitin Chains of Any Linkage Composition and Isotopic Labeling Scheme

(2011) Carlos Castañeda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Defining the geometry of the two-component proteasome degron

(2011) Tomonao Inobe et al.   Nature Chemical Biology

Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNA

(2011) S. E. Tsutakawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanical stability of multidomain proteins and novel mechanical clamps

(2011) Mateusz Sikora et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange

(2010) Bret D Freudenthal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin not only serves as a tag but also assists degradation by inducing protein unfolding

(2010) T. Hagai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Folding of glycoproteins: toward understanding the biophysics of the glycosylation code

(2009) Dalit Shental-Bechor et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

ATP-dependent Proteases Differ Substantially in Their Ability to Unfold Globular Proteins

(2009) Prakash Koodathingal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Ubiquitin-binding domains — from structures to functions

(2009) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin degradation with its substrate, or as a monomer in a ubiquitination-independent mode, provides clues to proteasome regulation

(2009) N. Shabek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of Excluded Volume upon Protein Stability in Covalently Cross-Linked Proteins with Variable Linker Lengths†

(2008) Yun Ho Kim et al.   BIOCHEMISTRY

Studying the folding of multidomain proteins

(2008) Sarah Batey et al.   HFSP Journal

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Large-Scale Analysis of Thermostable, Mammalian Proteins Provides Insights into the Intrinsically Disordered Proteome

(2008) Charles A. Galea et al.   JOURNAL OF PROTEOME RESEARCH

The N-end rule at atomic resolution

(2008) Alexander Varshavsky   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cooperativity, connectivity, and folding pathways of multidomain proteins

(2008) K. Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of glycosylation on protein folding: A close look at thermodynamic stabilization

(2008) D. Shental-Bechor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recognition Dynamics Up to Microseconds Revealed from an RDC-Derived Ubiquitin Ensemble in Solution

(2008) O. F. Lange et al.   SCIENCE