Structure-based directed evolution of a monomeric triosephosphate isomerase: toward a pentose sugar isomerase

L-Arabinose isomerase and its use for biotechnological production of rare sugars

(2014) Zheng Xu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enzyme architecture: on the importance of being in a protein cage

(2014) John P Richard et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Polishing the craft of genetic diversity creation in directed evolution

(2013) Kang Lan Tee et al.   BIOTECHNOLOGY ADVANCES

Mini-scale cultivation method enables expeditious plasmid production inEscherichia coli

(2013) Petra Grunzel et al.   Biotechnology Journal

Protein engineering of enzymes for process applications

(2013) John M Woodley   CURRENT OPINION IN CHEMICAL BIOLOGY

Precision is essential for efficient catalysis in an evolved Kemp eliminase

(2013) Rebecca Blomberg et al.   NATURE

A Paradigm for Enzyme-Catalyzed Proton Transfer at Carbon: Triosephosphate Isomerase

(2012) John P. Richard   BIOCHEMISTRY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Bridging the gaps in design methodologies by evolutionary optimization of the stability and proficiency of designed Kemp eliminase KE59

(2012) O. Khersonsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perspectives of biotechnological production of l-ribose and its purification

(2011) Chao Hu et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Strategy and success for the directed evolution of enzymes

(2011) Paul A Dalby   CURRENT OPINION IN STRUCTURAL BIOLOGY

Creation of Metal-Independent Hyperthermophilicl-Arabinose Isomerase by Homologous Recombination

(2011) Young-Ho Hong et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Evolutionary Walk between (β/α)8 Barrels: Catalytic Migration from Triosephosphate Isomerase to Thiamin Phosphate Synthase

(2011) Gloria Saab-Rincón et al.   JOURNAL OF MOLECULAR BIOLOGY

Crystallographic binding studies with an engineered monomeric variant of triosephosphate isomerase

(2010) Mikko Salin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Triosephosphate isomerase: a highly evolved biocatalyst

(2010) R. K. Wierenga et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Status of protein engineering for biocatalysts: how to design an industrially useful biocatalyst

(2010) Andreas S Bommarius et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Metal Ion Roles and the Movement of Hydrogen during Reaction Catalyzed by D-Xylose Isomerase: A Joint X-Ray and Neutron Diffraction Study

(2010) Andrey Y. Kovalevsky et al.   STRUCTURE

Directed evolution of enzymes: Library screening strategies

(2009) Hans Leemhuis et al.   IUBMB LIFE

Directed evolution drives the next generation of biocatalysts

(2009) Nicholas J Turner   Nature Chemical Biology

Establishing wild-type levels of catalytic activity on natural and artificial (  )8-barrel protein scaffolds

(2009) J. Claren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM

(2008) Markus Alahuhta et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties

(2008) M. Alahuhta et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Synthesis and pharmaceutical application of l-ribose

(2008) Kazuya Okano   TETRAHEDRON