Article
Neurosciences
Koorosh Mirpour, James W. Bisley
Summary: The lateral intraparietal area (LIP) provides a stable map integrating task rules and stimulus identity, while the frontal eye field (FEF) is consistently modulated by more complex information but integrates all information just before the saccade to make the final decision on where to move the eye.
JOURNAL OF NEUROPHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Panagiotis Sapountzis, Sofia Paneri, Sotirios Papadopoulos, Georgia G. Gregoriou
Summary: Recent work has shown that neural representations in the prefrontal cortex (PFC) are changing to adapt to task demands, but it is still unclear how this dynamic coding depends on the encoded variable and anatomical constraints. In this study, using a cued attention task and multivariate classification methods, the researchers found that neuronal ensembles in the PFC encode and retain spatial and color attentional instructions in a specific manner. Spatial instructions were decoded from both the frontal eye field (FEF) and the ventrolateral PFC (vlPFC) populations, while color instructions were decoded more robustly from vlPFC. The results suggest that dynamic population coding of attentional instructions in the PFC is influenced by anatomical constraints and can coexist with stable subspace coding.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2022)
Article
Neurosciences
Clara Bourrelly, Corentin Massot, Neeraj J. Gandhi
Summary: Sensorimotor transformation is the process of sensing and responding to stimuli, and this study investigates the neural activity in the superior colliculus during visually guided eye movements. The study compares spike bursts and local field potential (LFP) modulations along the dorsoventral axis of the superior colliculus and finds a transition from sensory to motor response in both signals, with the LFP transition occurring deeper than the spike burst transition. The results suggest a fast and efficient transformation between LFP modulation and spike burst during sensation, but not during action.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Acoustics
Kaleb A. Lowe, Wolf Zinke, M. Anthony Phipps, Josh Cosman, Micala Maddox, Jeffrey D. Schall, Charles F. Caskey
Summary: Research on focused ultrasound (FUS) stimulation directly applied over the macaque frontal eye field (FEF) through a craniotomy revealed that FUS can modulate saccadic responses in monkeys, affecting their saccade response times and error rates. FUS was found to have a regulatory effect on directing eye movements towards targets in visual search tasks.
ULTRASOUND IN MEDICINE AND BIOLOGY
(2021)
Article
Multidisciplinary Sciences
Domenica Veniero, Joachim Gross, Stephanie Morand, Felix Duecker, Alexander T. Sack, Gregor Thut
Summary: The activation of the Frontal Eye Fields can shape visual cortex activity and perception through mechanisms of oscillatory realignment at the beta frequency.
NATURE COMMUNICATIONS
(2021)
Review
Neurosciences
Mark A. Segraves
Summary: Using natural scenes as a research method provides insights into the functioning of visual and eye movement systems in everyday life. This review examines the findings from behavioral and neurophysiological studies using natural scene viewing in humans and monkeys. The use of natural scenes for studying cerebral cortical activity is relatively new and poses challenges for data analysis. The article presents methods and results from using natural scenes to study the visual and eye movement cortex, highlighting new insights that this approach offers to enhance our understanding of these cortical regions compared to conventional methods.
ANNUAL REVIEW OF VISION SCIENCE
(2023)
Article
Clinical Neurology
Valentina Barone, Maria Carla Piastra, Johannes P. van Dijk, Gerhard H. Visser, Mariette H. J. A. Debeij-van Hall, Michel J. A. M. van Putten
Summary: This study investigates the differences in cognitive and eye movement processes during seizures in pediatric patients with absences. It reveals that the involvement of the right frontal eye field is higher in patients with impaired eye movements compared to those with preserved eye movements during seizures. This finding has clinical significance for assessing visual attention in epilepsy patients and providing personalized advice.
CLINICAL NEUROPHYSIOLOGY
(2023)
Article
Multidisciplinary Sciences
Naveen Sendhilnathan, Debaleena Basu, Michael E. Goldberg, Jeffrey D. Schall, Aditya Murthy
Summary: The study revealed unexpected differences in neural signatures for goal-directed versus non-goal-directed movements in a brain area selectively implicated in voluntary control, adding critical constraints to the way we think about saccade generation in the brain.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Neurosciences
Kaleb A. Lowe, Wolf Zinke, Joshua D. Cosman, Jeffrey D. Schall
Summary: This study investigated the neuronal spiking modulation patterns in the FEF and F2vr areas of macaque monkeys. The results showed differences in the variety of modulation patterns, proportions of visuomotor neuron types, and consistency of modulation patterns across tasks between FEF and F2vr.
Article
Neurosciences
Chia-Chien Wu, Jeremy M. Wolfe
Summary: Observers do not fixate every location during visual search, instead processing occurs within a Functional Visual Field surrounding each fixation. Each fixation poses three questions, implying different senses of the FVF.
Article
Multidisciplinary Sciences
Frauke Heins, Jana Masselink, Joshua-Nikodemus Scherer, Markus Lappe
Summary: The study investigates whether oculomotor behavior can be adapted based on post-saccadic target information alone. The results suggest that, based on post-saccadic information, eye movements and target localization can be adjusted to reduce errors, possibly indicating a continuous updating of the estimated pre-saccadic target location driven by postdictive motor error.
SCIENTIFIC REPORTS
(2023)
Article
Multidisciplinary Sciences
J. L. Amengual, F. Di Bello, S. Ben Hadj Hassen, Suliann Ben Hamed
Summary: This study presents findings that optimal behavioral performance is a result of the absence of interference between internal neural states and attention control. In addition to encoding spatial attention, prefrontal neurons also encode a distractibility-to-impulsivity state. The study identifies two partially overlapping neuronal subpopulations associated either with the focus of attention or overt behavior, and describes the neural variability accounting for distractibility-to-impulsivity behavior.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Alexia Bourgeois, Virginie Sterpenich, Giannina Rita Iannotti, Patrik Vuilleumier
Summary: The study found that reward cues can selectively modulate the Frontal Eye Field (FEF) during attentional shifts, especially after high-predictive cueing to invalid locations. Reward information also modulated FEF connectivity to superior colliculus, striatum, and visual cortex.
Article
Neurosciences
Qiong Zhang, Weifeng Sun, Kailing Huang, Li Qin, Shirui Wen, Xiaoyan Long, Quan Wang, Li Feng
Summary: This study explored the characteristics and mechanisms of working memory impairment in patients with frontal lobe epilepsy (FLE) using a memory game paradigm and eye tracking technology. The results showed that FLE patients had lower memory scores and took longer to complete the memory game compared to healthy controls. Eye tracking data also revealed deficits in attentional maintenance among FLE patients. These findings contribute to understanding the underlying mechanisms of memory impairment in FLE.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Psychology, Experimental
Anna Nowakowska, Alasdair D. F. Clarke, Josephine Reuther, Amelia R. Hunt
Summary: This study compares eye movement strategies across different stimulus sets and finds that eye movements are guided by expected information gain. When searching for a simple target based on orientation, people vary in their eye movements and often look at locations where peripheral vision is sufficient for determining the target's presence. In contrast, when searching for a target based on identity, eye movements are similar and directed towards locations where central vision is most needed.
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-GENERAL
(2023)
