Hantavirus GnT Elements Mediate TRAF3 Binding and Inhibit RIG-I/TBK1-Directed Beta Interferon Transcription by Blocking IRF3 Phosphorylation

The E3 Ubiquitin Ligase Ro52 Negatively Regulates IFN-  Production Post-Pathogen Recognition by Polyubiquitin-Mediated Degradation of IRF3

(2014) R. Higgs et al.   JOURNAL OF IMMUNOLOGY

Trim21: a novel negative regulator in DNA sensor signaling

(2013) Bo Yang et al.   Cellular & Molecular Immunology

FoxO1 Negatively Regulates Cellular Antiviral Response by Promoting Degradation of IRF3

(2013) Cao-Qi Lei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3

(2013) Hongbo Hu et al.   NATURE

RING Finger Protein 11 Targets TBK1/IKKi Kinases to Inhibit Antiviral Signaling

(2013) Soratree Charoenthongtrakul et al.   PLoS One

An Interferon Paradox

(2013) P. M. Odorizzi et al.   SCIENCE

Persistent LCMV Infection Is Controlled by Blockade of Type I Interferon Signaling

(2013) J. R. Teijaro et al.   SCIENCE

IKKε-Mediated Tumorigenesis Requires K63-Linked Polyubiquitination by a cIAP1/cIAP2/TRAF2 E3 Ubiquitin Ligase Complex

(2013) Alicia Y. Zhou et al.   Cell Reports

Structure and Ubiquitination-Dependent Activation of TANK-Binding Kinase 1

(2013) Daqi Tu et al.   Cell Reports

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

(2013) Helen M. Lazear et al.   PLoS Pathogens

Linear Ubiquitination of NEMO Negatively Regulates the Interferon Antiviral Response through Disruption of the MAVS-TRAF3 Complex

(2012) S. Mehdi Belgnaoui et al.   Cell Host & Microbe

Regulation of the innate immune system by ubiquitin and ubiquitin-like modifiers

(2012) Diede Oudshoorn et al.   CYTOKINE & GROWTH FACTOR REVIEWS

TRAF-interacting protein (TRIP) negatively regulates IFN-β production and antiviral response by promoting proteasomal degradation of TANK-binding kinase 1

(2012) Meng Zhang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The E3 ubiquitin ligase TRIM21 negatively regulates the innate immune response to intracellular double-stranded DNA

(2012) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

Tyrosine Phosphorylation of the E3 Ubiquitin Ligase TRIM21 Positively Regulates Interaction with IRF3 and Hence TRIM21 Activity

(2012) Kevin B. Stacey et al.   PLoS One

MIP-T3 Is a Negative Regulator of Innate Type I IFN Response

(2011) M.-H. J. Ng et al.   JOURNAL OF IMMUNOLOGY

UXT-V1 Facilitates the Formation of MAVS Antiviral Signalosome on Mitochondria

(2011) Y. Huang et al.   JOURNAL OF IMMUNOLOGY

The C-Terminal 42 Residues of the Tula Virus Gn Protein Regulate Interferon Induction

(2011) V. Matthys et al.   JOURNAL OF VIROLOGY

The Ubiquitin E3 Ligase RAUL Negatively Regulates Type I Interferon through Ubiquitination of the Transcription Factors IRF7 and IRF3

(2010) Yanxing Yu et al.   IMMUNITY

Virus-triggered Ubiquitination of TRAF3/6 by cIAP1/2 Is Essential for Induction of Interferon-β (IFN-β) and Cellular Antiviral Response

(2010) Ai-Ping Mao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cytoplasmic tails of hantavirus glycoproteins interact with the nucleocapsid protein

(2010) J. Hepojoki et al.   JOURNAL OF GENERAL VIROLOGY

Antagonism of Type I Interferon Responses by New World Hantaviruses

(2010) J. R. Levine et al.   JOURNAL OF VIROLOGY

Emerging roles for the non-canonical IKKs in cancer

(2010) R R Shen et al.   ONCOGENE

Ubiquitin-Regulated Recruitment of I B Kinase   to the MAVS Interferon Signaling Adapter

(2009) S. Paz et al.   MOLECULAR AND CELLULAR BIOLOGY

The enhanceosome

(2008) Daniel Panne   CURRENT OPINION IN STRUCTURAL BIOLOGY

The NY-1 Hantavirus Gn Cytoplasmic Tail Coprecipitates TRAF3 and Inhibits Cellular Interferon Responses by Disrupting TBK1-TRAF3 Complex Formation

(2008) P. J. Alff et al.   JOURNAL OF VIROLOGY