Predicting the Impact of CD8+ T Cell Polyfunctionality on HIV Disease Progression

A Randomized, Double-Blind, Placebo-Controlled Assessment of BMS-936558, a Fully Human Monoclonal Antibody to Programmed Death-1 (PD-1), in Patients with Chronic Hepatitis C Virus Infection

(2013) David Gardiner et al.   PLoS One

Can Non-lytic CD8+ T Cells Drive HIV-1 Escape?

(2013) Nafisa-Katrin Seich al Basatena et al.   PLoS Pathogens

Comparison of cytotoxic T lymphocyte efficacy in acute and persistent lymphocytic choriomeningitis virus infection

(2011) F. Graw et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Quantification of the Relative Importance of CTL, B Cell, NK Cell, and Target Cell Limitation in the Control of Primary SIV-Infection

(2011) Marjet Elemans et al.   PLoS Computational Biology

Why Don't CD8+ T Cells Reduce the Lifespan of SIV-Infected Cells In Vivo?

(2011) Marjet Elemans et al.   PLoS Computational Biology

Living in a house of cards: re-evaluating CD8+ T-cell immune correlates against HIV

(2010) George Makedonas et al.   IMMUNOLOGICAL REVIEWS

Persistence of viral infection despite similar killing efficacy of antiviral CD8+ T cells during acute and chronic phases of infection

(2010) Vitaly V. Ganusov et al.   VIROLOGY

CD8+ Lymphocytes Control Viral Replication in SIVmac239-Infected Rhesus Macaques without Decreasing the Lifespan of Productively Infected Cells

(2010) Nichole R. Klatt et al.   PLoS Pathogens

In Vivo CD8+ T-Cell Suppression of SIV Viremia Is Not Mediated by CTL Clearance of Productively Infected Cells

(2010) Joseph K. Wong et al.   PLoS Pathogens

Many cytokines are very useful therapeutic targets in disease

(2008) Marc Feldmann   JOURNAL OF CLINICAL INVESTIGATION

Emergence of Polyfunctional CD8+ T Cells after Prolonged Suppression of Human Immunodeficiency Virus Replication by Antiretroviral Therapy

(2008) M. Rehr et al.   JOURNAL OF VIROLOGY

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Enhancing SIV-specific immunity in vivo by PD-1 blockade

(2008) Vijayakumar Velu et al.   NATURE

Abundance of Early Functional HIV-Specific CD8+ T Cells Does Not Predict AIDS-Free Survival Time

(2008) Ingrid M. M. Schellens et al.   PLoS One

Dynamics of Immune Escape during HIV/SIV Infection

(2008) Christian L. Althaus et al.   PLoS Computational Biology