Differentiation of Neurons Restricts Arbovirus Replication and Increases Expression of the Alpha Isoform of IRF-7

Virus-Induced Transcriptional Changes in the Brain Include the Differential Expression of Genes Associated with Interferon, Apoptosis, Interleukin 17 Receptor A, and Glutamate Signaling as Well as Flavivirus-Specific Upregulation of tRNA Synthetases

(2014) P. Clarke et al.   mBio

Activation of the Type I Interferon Pathway Is Enhanced in Response to Human Neuronal Differentiation

(2013) Jocelyn R. Farmer et al.   PLoS One

A Systems Biology Approach Reveals that Tissue Tropism to West Nile Virus Is Regulated by Antiviral Genes and Innate Immune Cellular Processes

(2013) Mehul S. Suthar et al.   PLoS Pathogens

Complexity of the Microglial Activation Pathways that Drive Innate Host Responses During Lethal Alphavirus Encephalitis in Mice

(2012) Nilufer Esen et al.   ASN Neuro

Cutting Edge: Independent Roles for IRF-3 and IRF-7 in Hematopoietic and Nonhematopoietic Cells during Host Response to Chikungunya Infection

(2012) C. Schilte et al.   JOURNAL OF IMMUNOLOGY

STAT1-Independent Control of a Neurotropic Measles Virus Challenge in Primary Neurons and Infected Mice

(2012) L. A. O'Donnell et al.   JOURNAL OF IMMUNOLOGY

Early Events in Alphavirus Replication Determine the Outcome of Infection

(2012) I. Frolov et al.   JOURNAL OF VIROLOGY

Virus-Activated Interferon Regulatory Factor 7 Upregulates Expression of the Interferon-Regulated BST2 Gene Independently of Interferon Signaling

(2012) M. G. Bego et al.   JOURNAL OF VIROLOGY

Differential Impact of Interferon Regulatory Factor 7 in Initiation of the Type I Interferon Response in the Lymphocytic Choriomeningitis Virus-Infected Central Nervous System versus the Periphery

(2012) J. E. Christensen et al.   JOURNAL OF VIROLOGY

Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-Mediated Neuronal Responses That Are Cytoprotective, Interferon Independent, and Inhibited by Western Equine Encephalitis Virus Capsid

(2012) Daniel C. Peltier et al.   JOURNAL OF VIROLOGY

Interferon-Induced Ifit2/ISG54 Protects Mice from Lethal VSV Neuropathogenesis

(2012) Volker Fensterl et al.   PLoS Pathogens

RIG-I-like receptors: cytoplasmic sensors for non-self RNA

(2011) Hiroki Kato et al.   IMMUNOLOGICAL REVIEWS

Type I interferon signaling limits reoviral tropism within the brain and prevents lethal systemic infection

(2011) Kalen R. Dionne et al.   JOURNAL OF NEUROVIROLOGY

The type I interferon response bridles rabies virus infection and reduces pathogenicity

(2011) Damien Chopy et al.   JOURNAL OF NEUROVIROLOGY

The Role of Interferon Antagonist, Non-Structural Proteins in the Pathogenesis and Emergence of Arboviruses

(2011) Bradley S. Hollidge et al.   Viruses-Basel

Interferon Antagonist NSs of La Crosse Virus Triggers a DNA Damage Response-like Degradation of Transcribing RNA Polymerase II

(2010) Paul Verbruggen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammasome signaling at the heart of central nervous system pathology

(2010) Swarupa Chakraborty et al.   JOURNAL OF NEUROSCIENCE RESEARCH

TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN

(2009) J. Di Domizio et al.   BLOOD

Interaction of Sindbis virus non-structural protein 3 with poly(ADP-ribose) polymerase 1 in neuronal cells

(2009) E. Park et al.   JOURNAL OF GENERAL VIROLOGY

Novel Reporter Mouse Reveals Constitutive and Inflammatory Expression of IFN-  In Vivo

(2009) S. Lienenklaus et al.   JOURNAL OF IMMUNOLOGY

Similarities and Differences in Antagonism of Neuron Alpha/Beta Interferon Responses by Venezuelan Equine Encephalitis and Sindbis Alphaviruses

(2009) J. Yin et al.   JOURNAL OF VIROLOGY

Noncytolytic Clearance of Sindbis Virus Infection from Neurons by Gamma Interferon Is Dependent on Jak/Stat Signaling

(2009) R. Burdeinick-Kerr et al.   JOURNAL OF VIROLOGY

Interferon Regulatory Factor IRF-7 Induces the Antiviral Alpha Interferon Response and Protects against Lethal West Nile Virus Infection

(2008) S. Daffis et al.   JOURNAL OF VIROLOGY

Translational control of the innate immune response through IRF-7

(2008) Rodney Colina et al.   NATURE

La Crosse virus infectivity, pathogenesis, and immunogenicity in mice and monkeys

(2008) Richard S Bennett et al.   Virology Journal

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY

Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons

(2007) Kathryn M. Castorena et al.   VIROLOGY