Novel H7N9 Influenza Virus Shows Low Infectious Dose, High Growth Rate, and Efficient Contact Transmission in the Guinea Pig Model

Novel Avian-Origin Influenza A (H7N9) Virus Attaches to Epithelium in Both Upper and Lower Respiratory Tract of Humans

(2013) Debby van Riel et al.   AMERICAN JOURNAL OF PATHOLOGY

Glycan Receptor Binding of the Influenza A Virus H7N9 Hemagglutinin

(2013) Kannan Tharakaraman et al.   CELL

H7N9 influenza viruses interact preferentially with  2,3-linked sialic acids and bind weakly to  2,6-linked sialic acids

(2013) I. Ramos et al.   JOURNAL OF GENERAL VIROLOGY

A case of avian influenza A (H7N9) virus occurring in the summer season, China

(2013) Peng Yang et al.   JOURNAL OF INFECTION

Novel Avian-Origin Human Influenza A(H7N9) Can Be Transmitted Between Ferrets via Respiratory Droplets

(2013) Lili Xu et al.   JOURNAL OF INFECTIOUS DISEASES

Reassortment Complements Spontaneous Mutation in Influenza A Virus NP and M1 Genes To Accelerate Adaptation to a New Host

(2013) W. L. Ince et al.   JOURNAL OF VIROLOGY

Increased Acid Stability of the Hemagglutinin Protein Enhances H5N1 Influenza Virus Growth in the Upper Respiratory Tract but Is Insufficient for Transmission in Ferrets

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

The first case of H7N9 influenza in Taiwan

(2013) Sui-Yuan Chang et al.   LANCET

Pathogenesis and transmission of avian influenza A (H7N9) virus in ferrets and mice

(2013) Jessica A. Belser et al.   NATURE

Limited airborne transmission of H7N9 influenza A virus between ferrets

(2013) Mathilde Richard et al.   NATURE

Receptor binding by an H7N9 influenza virus from humans

(2013) Xiaoli Xiong et al.   NATURE

Characterization of H7N9 influenza A viruses isolated from humans

(2013) Tokiko Watanabe et al.   NATURE

Clinical Findings in 111 Cases of Influenza A (H7N9) Virus Infection

(2013) Hai-Nv Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China

(2013) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Infectivity, Transmission, and Pathology of Human-Isolated H7N9 Influenza Virus in Ferrets and Pigs

(2013) H. Zhu et al.   SCIENCE

H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

(2013) Y. Zhang et al.   SCIENCE

Structures and Receptor Binding of Hemagglutinins from Human-Infecting H7N9 Influenza Viruses

(2013) Y. Shi et al.   SCIENCE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

Low pathogenic avian influenza A(H7N9) virus causes high mortality in ferrets upon intratracheal challenge: A model to study intervention strategies

(2013) J.H.C.M. Kreijtz et al.   VACCINE

The Novel Human Influenza A(H7N9) Virus Is Naturally Adapted to Efficient Growth in Human Lung Tissue

(2013) J. Knepper et al.   mBio

Probable person to person transmission of novel avian influenza A (H7N9) virus in Eastern China, 2013: epidemiological investigation

(2013) X. Qi et al.   BMJ-British Medical Journal

Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

(2013) Summer E. Galloway et al.   PLoS Pathogens

Influenza A Viruses Target Type II Pneumocytes in the Human Lung

(2012) V. K. Weinheimer et al.   JOURNAL OF INFECTIOUS DISEASES

Transmission of Influenza B Viruses in the Guinea Pig

(2012) Natalie Pica et al.   JOURNAL OF VIROLOGY

Pandemic 2009 H1N1 Influenza A Virus Carrying a Q136K Mutation in the Neuraminidase Gene Is Resistant to Zanamivir but Exhibits Reduced Fitness in the Guinea Pig Transmission Model

(2012) Michael M. Kaminski et al.   JOURNAL OF VIROLOGY

Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets

(2012) Masaki Imai et al.   NATURE

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The M Segment of the 2009 New Pandemic H1N1 Influenza Virus Is Critical for Its High Transmission Efficiency in the Guinea Pig Model

(2011) Y.-y. Chou et al.   JOURNAL OF VIROLOGY

Cold-Adapted Influenza and Recombinant Adenovirus Vaccines Induce Cross-Protective Immunity against pH1N1 Challenge in Mice

(2011) Mark R. Soboleski et al.   PLoS One

Seasonal and Pandemic Human Influenza Viruses Attach Better to Human Upper Respiratory Tract Epithelium than Avian Influenza Viruses

(2010) Debby van Riel et al.   AMERICAN JOURNAL OF PATHOLOGY

Transmission of a 2009 Pandemic Influenza Virus Shows a Sensitivity to Temperature and Humidity Similar to That of an H3N2 Seasonal Strain

(2010) J. Steel et al.   JOURNAL OF VIROLOGY

Virulence-Associated Substitution D222G in the Hemagglutinin of 2009 Pandemic Influenza A(H1N1) Virus Affects Receptor Binding

(2010) S. Chutinimitkul et al.   JOURNAL OF VIROLOGY

Oseltamivir-Resistant Variants of the 2009 Pandemic H1N1 Influenza A Virus Are Not Attenuated in the Guinea Pig and Ferret Transmission Models

(2010) C. W. Seibert et al.   JOURNAL OF VIROLOGY

Guinea Pig Model for Evaluating the Potential Public Health Risk of Swine and Avian Influenza Viruses

(2010) Yipeng Sun et al.   PLoS One

Structural Basis of Preexisting Immunity to the 2009 H1N1 Pandemic Influenza Virus

(2010) R. Xu et al.   SCIENCE

Histopathology and growth kinetics of influenza viruses (H1N1 and H3N2) in the upper and lower airways of guinea pigs

(2009) X. Tang et al.   JOURNAL OF GENERAL VIROLOGY

Transmission of Influenza Virus via Aerosols and Fomites in the Guinea Pig Model

(2009) Samira Mubareka et al.   JOURNAL OF INFECTIOUS DISEASES

Transmission of Pandemic H1N1 Influenza Virus and Impact of Prior Exposure to Seasonal Strains or Interferon Treatment

(2009) J. Steel et al.   JOURNAL OF VIROLOGY

Pathogenesis of 1918 Pandemic and H5N1 Influenza Virus Infections in a Guinea Pig Model: Antiviral Potential of Exogenous Alpha Interferon To Reduce Virus Shedding

(2009) N. Van Hoeven et al.   JOURNAL OF VIROLOGY

Structure, Receptor Binding, and Antigenicity of Influenza Virus Hemagglutinins from the 1957 H2N2 Pandemic

(2009) R. Xu et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

Blocking Interhost Transmission of Influenza Virus by Vaccination in the Guinea Pig Model

(2009) A. C. Lowen et al.   JOURNAL OF VIROLOGY

Structures of receptor complexes formed by hemagglutinins from the Asian Influenza pandemic of 1957

(2009) J. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies

(2008) Fabrice Carrat et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

High Temperature (30 C) Blocks Aerosol but Not Contact Transmission of Influenza Virus

(2008) A. C. Lowen et al.   JOURNAL OF VIROLOGY

Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol

(2008) N. M. Bouvier et al.   JOURNAL OF VIROLOGY

Bronchointerstitial Pneumonia in Guinea Pigs Following Inoculation with H5N1 High Pathogenicity Avian Influenza Virus

(2008) Y. K. Kwon et al.   VETERINARY PATHOLOGY