Frequent and Variable Cytotoxic-T-Lymphocyte Escape-Associated Fitness Costs in the Human Immunodeficiency Virus Type 1 Subtype B Gag Proteins

Vaccine Design for CD8 T Lymphocyte Responses

(2013) R. A. Koup et al.   Cold Spring Harbor Perspectives in Medicine

Impact of HLA-B*81-Associated Mutations in HIV-1 Gag on Viral Replication Capacity

(2012) J. K. Wright et al.   JOURNAL OF VIROLOGY

Correlates of Protective Cellular Immunity Revealed by Analysis of Population-Level Immune Escape Pathways in HIV-1

(2012) J. M. Carlson et al.   JOURNAL OF VIROLOGY

Widespread Impact of HLA Restriction on Immune Control and Escape Pathways of HIV-1

(2012) J. M. Carlson et al.   JOURNAL OF VIROLOGY

Differential Clade-Specific HLA-B*3501 Association with HIV-1 Disease Outcome Is Linked to Immunogenicity of a Single Gag Epitope

(2012) P. C. Matthews et al.   JOURNAL OF VIROLOGY

Loss of HIV-1-derived cytotoxic T lymphocyte epitopes restricted by protective HLA-B alleles during the HIV-1 epidemic

(2011) Ingrid M.M. Schellens et al.   AIDS

Atomic-level modelling of the HIV capsid

(2011) Owen Pornillos et al.   NATURE

Profound early control of highly pathogenic SIV by an effector memory T-cell vaccine

(2011) Scott G. Hansen et al.   NATURE

HIV Immune Escape at an Immunodominant Epitope in HLA-B*27-Positive Individuals Predicts Viral Load Outcome

(2010) P. Ammaranond et al.   JOURNAL OF IMMUNOLOGY

Early Selection in Gag by Protective HLA Alleles Contributes to Reduced HIV-1 Replication Capacity That May Be Largely Compensated for in Chronic Infection

(2010) M. A. Brockman et al.   JOURNAL OF VIROLOGY

The Major Genetic Determinants of HIV-1 Control Affect HLA Class I Peptide Presentation

(2010)   SCIENCE

X-Ray Structures of the Hexameric Building Block of the HIV Capsid

(2009) Owen Pornillos et al.   CELL

The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection

(2009) Nilu Goonetilleke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Immunodeficiency Virus Type 1-Specific CD8+ T-Cell Responses during Primary Infection Are Major Determinants of the Viral Set Point and Loss of CD4+ T Cells

(2009) H. Streeck et al.   JOURNAL OF VIROLOGY

Adaptation of HIV-1 to human leukocyte antigen class I

(2009) Yuka Kawashima et al.   NATURE

Effector memory T cell responses are associated with protection of rhesus monkeys from mucosal simian immunodeficiency virus challenge

(2009) Scott G Hansen et al.   NATURE MEDICINE

HLA-Associated Immune Escape Pathways in HIV-1 Subtype B Gag, Pol and Nef Proteins

(2009) Zabrina L. Brumme et al.   PLoS One

Transmission of HIV-1 Gag immune escape mutations is associated with reduced viral load in linked recipients

(2008) Paul A. Goepfert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Structural and Functional Constraints Limit Options for Cytotoxic T-Lymphocyte Escape in the Immunodominant HLA-B27-Restricted Epitope in Human Immunodeficiency Virus Type 1 Capsid

(2008) A. Schneidewind et al.   JOURNAL OF VIROLOGY

Reduced Viral Replication Capacity of Human Immunodeficiency Virus Type 1 Subtype C Caused by Cytotoxic-T-Lymphocyte Escape Mutations in HLA-B57 Epitopes of Capsid Protein

(2008) C. L. Boutwell et al.   JOURNAL OF VIROLOGY

Functional Consequences of Human Immunodeficiency Virus Escape from an HLA-B*13-Restricted CD8+ T-Cell Epitope in p1 Gag Protein

(2008) J. G. Prado et al.   JOURNAL OF VIROLOGY

Protective HLA Class I Alleles That Restrict Acute-Phase CD8+ T-Cell Responses Are Associated with Viral Escape Mutations Located in Highly Conserved Regions of Human Immunodeficiency Virus Type 1

(2008) Y. E. Wang et al.   JOURNAL OF VIROLOGY

Central Role of Reverting Mutations in HLA Associations with Human Immunodeficiency Virus Set Point

(2008) P. C. Matthews et al.   JOURNAL OF VIROLOGY

Transmission of HIV-1 CTL Escape Variants Provides HLA-Mismatched Recipients with a Survival Advantage

(2008) Denis R. Chopera et al.   PLoS Pathogens