Replicating Adenovirus-Simian Immunodeficiency Virus (SIV) Recombinant Priming and Envelope Protein Boosting Elicits Localized, Mucosal IgA Immunity in Rhesus Macaques Correlated with Delayed Acquisition following a Repeated Low-Dose Rectal SIVmac251Challenge

Simultaneous Approach Using Systemic, Mucosal and Transcutaneous Routes of Immunization For Development of Protective HIV-1 Vaccines

(2011) I.M. Belyakov et al.   CURRENT MEDICINAL CHEMISTRY

HIV Vaccine efficacy trial: Glimmers of hope and the potential role of antibody-dependent cellular cytotoxicity

(2011) Leia Wren et al.   Human vaccines & immunotherapeutics

Durable Mucosal Simian Immunodeficiency Virus-Specific Effector Memory T Lymphocyte Responses Elicited by Recombinant Adenovirus Vectors in Rhesus Monkeys

(2011) H. Li et al.   JOURNAL OF VIROLOGY

TRIM5  Does Not Affect Simian Immunodeficiency Virus SIVmac251 Replication in Vaccinated or Unvaccinated Indian Rhesus Macaques following Intrarectal Challenge Exposure

(2011) C. Fenizia et al.   JOURNAL OF VIROLOGY

Adenovirus type 5 induces vitamin A-metabolizing enzymes in dendritic cells and enhances priming of gut-homing CD8 T cells

(2011) S Ganguly et al.   Mucosal Immunology

Mucosal memory CD8+ T cells are selected in the periphery by an MHC class I molecule

(2011) Yujun Huang et al.   NATURE IMMUNOLOGY

Vaccine-elicited SIV and HIV envelope-specific IgA and IgG memory B cells in rhesus macaque peripheral blood correlate with functional antibody responses and reduced viremia

(2011) Egidio Brocca-Cofano et al.   VACCINE

Partial efficacy of a VSV-SIV/MVA-SIV vaccine regimen against oral SIV challenge in infant macaques

(2011) Marta L. Marthas et al.   VACCINE

Rapid SIV Env-specific mucosal and serum antibody induction augments cellular immunity in protecting immunized, elite-controller macaques against high dose heterologous SIV challenge

(2011) L. Jean Patterson et al.   VIROLOGY

Sublingual Administration of an Adenovirus Serotype 5 (Ad5)-Based Vaccine Confirms Toll-Like Receptor Agonist Activity in the Oral Cavity and Elicits Improved Mucosal and Systemic Cell-Mediated Responses against HIV Antigens despite Preexisting Ad5 Immunity

(2010) Daniel M. Appledorn et al.   Clinical and Vaccine Immunology

Route of Adenovirus-Based HIV-1 Vaccine Delivery Impacts the Phenotype and Trafficking of Vaccine-Elicited CD8+ T Lymphocytes

(2010) D. R. Kaufman et al.   JOURNAL OF VIROLOGY

Multiple Vaccine-Elicited Nonneutralizing Antienvelope Antibody Activities Contribute to Protective Efficacy by Reducing both Acute and Chronic Viremia following Simian/Human Immunodeficiency Virus SHIV89.6P Challenge in Rhesus Macaques

(2010) P. Xiao et al.   JOURNAL OF VIROLOGY

Low-Dose Mucosal Simian Immunodeficiency Virus Infection Restricts Early Replication Kinetics and Transmitted Virus Variants in Rhesus Monkeys

(2010) J. Liu et al.   JOURNAL OF VIROLOGY

Sublingual immunization with an HIV subunit vaccine induces antibodies and cytotoxic T cells in the mouse female genital tract

(2010) Catherine Hervouet et al.   VACCINE

TLR, NLR Agonists, and Other Immune Modulators as Infectious Disease Vaccine Adjuvants

(2010) Sarah C. Higgins et al.   Current Infectious Disease Reports

Tonsillar Application of AT-2 SIV Affords Partial Protection Against Rectal Challenge With SIVmac239

(2009) Panagiotis Vagenas et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1

(2009) Brandon F. Keele et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Analysis of humoral immune responses in rhesus macaques vaccinated with attenuated SIVmac239Δnefand challenged with pathogenic SIVmac251

(2009) Doris Freißmuth et al.   JOURNAL OF MEDICAL PRIMATOLOGY

Molecular methods for evaluation of virological status of nonhuman primates challenged with simian immunodeficiency or simian-human immunodeficiency viruses

(2009) Eun Mi Lee et al.   JOURNAL OF VIROLOGICAL METHODS

Vaccination with ALVAC and AIDSVAX to Prevent HIV-1 Infection in Thailand

(2009) Supachai Rerks-Ngarm et al.   NEW ENGLAND JOURNAL OF MEDICINE

Replicating adenovirus vector prime/protein boost strategies for HIV vaccine development

(2008) L Jean Patterson et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Correlation of Vaccine-Elicited Systemic and Mucosal Nonneutralizing Antibody Activities with Reduced Acute Viremia following Intrarectal Simian Immunodeficiency Virus SIVmac251 Challenge of Rhesus Macaques

(2008) R. Hidajat et al.   JOURNAL OF VIROLOGY

Failure of the Merck HIV vaccine: an uncertain step forward

(2008) Merlin L Robb   LANCET

Efficacy assessment of a cell-mediated immunity HIV-1 vaccine (the Step Study): a double-blind, randomised, placebo-controlled, test-of-concept trial

(2008) Susan P Buchbinder et al.   LANCET

Sublingual Immunotherapy

(2008) Anthony J. Frew   NEW ENGLAND JOURNAL OF MEDICINE

Sublingual vaccination with influenza virus protects mice against lethal viral infection

(2008) J.-H. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection

(2008) B. F. Keele et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic neutralizing antibodies induced by long interval mucosally primed systemically boosted immunization correlate with protection from mucosal SHIV challenge

(2008) Willy M.J.M. Bogers et al.   VIROLOGY